Bo and Luke have left Hazzard to full fill a life long dream of racing on the NASCAR Circuit. Boss is so happy about it, that he unleashes his ultimate secret weapon: The mean green machine, monstrous vehicle to rip off the bank in Capitol City, and plan to steal $100 engraving plates from an armored truck that's suppose to pass through Hazzard county. But he's unaware that cousins Coy and Vance Duke have returned to Hazzard after 6 years to help uncle Jesse run the farm and are on to his shenanigans, and driving around in the General Lee. Also, Enos returned to Hazzard and is back on the force.

Boss Hogg swindles newlyweds Jeb and Carrie Morton into buying a worthless piece of land next to the Duke Farm. So the Dukes try and help them by scamming Boss by making it look like they've found gold on their property and the Morton's property and struck it rich so that Boss will buy back the land.

Boss hired two crooks to rob the jewelry store and Coy and Vance are very suspicious about them and go and investigate while being chased by Cletus and Enos. But when Boss sends Rosco to arrest Coy and Vance, he refuses because he wants to be good so that he will be elected "Lawman of the Year".

While delivering a shipment of antiques to some friends, Coy and Vance are hijacked by a couple of Boss' henchmen. But they didn't known that a runaway orphan was stowaway in the back of the truck and saw the whole thing. She ends up going back to the farm and has crush on Coy, which slows down the Dukes looking for the hijackers.

Boss double-crosses the Bosses of a few neighboring counties and their out to get him. The Dukes let him hold up on the farm until Vance plans to expose them by tape-recording their scheme. Mel Tillis performs at the Boar's Nest.

Boss frames Coy and Vance by putting a hot license plate on the General Lee. But Boss calls off the chase when he is told that his daddy is coming to Hazzard who is supposedly a Good Samaritan - but his driver robs them.

Vance's old girlfriend comes to Hazzard to see him but is chased by crooked politician's associates who are trying to kill her after she witnessed the Senator's embezzling. . But The Duke try and convince her to go report it to Senate Crime Commission.

Boss opens up an illegal horse-betting saloon in Rapahoe County and uses the Dukes' phone line to frame them. But the Boss of Rapahoe County is not happy being cheated out of her county's money.

A pair of crooks is after Enos' footlocker that he and the Dukes picked up at the bus depot from California that contains a handful of emeralds - unbeknownst to Enos.

Boss Hogg's phony insurance policies are thrown right back at him when con artists Ward and Lavinia pull a phony car accident at Bottomless Lake. But to make matters worse, Coy is afraid of driving since he was sideswiped during the accident and he believes he killed Ward.

Boss Hogg is trying to get his hands on the General Lee to sell to two crooks that need it. But when they try and steal it, they get caught. So Boss challenges Jesse to a game of pool - Ridge runner style - and wagers the General Lee. Even though Jesse's a better pool player, Boss has some dirty tricks up his sleeve.

Boss has Coy, Vance and Daisy framed and sends them to Chickasaw County where they are arrested by Sheriff Little so that he can go ahead with his master plan and hires two crooks to scuba-dive down to Soggy Marsh and unburry 5 million in stolen bonds.

When Rosco is up for re-election, Boss has no trouble supporting him until his devious nephew Hughie Hogg returns to run for sheriff and blackmails his uncle into helping him by showing evidence of a crooked deal he made.

Boss tries to use the mean green machine again but it gets stolen by the original crook who try and rob the Hazzard Emporium for all the gold. But when it breaks down, they kidnap Cooter to fix it and hold for insurance.

A mobster named Calloway is out to exact revenge on "the fat water buffalo" (Boss), for sending him to prison on his testimony. To thwart Calloway's plans to have Boss killed, the Dukes and Lulu announce that Boss has died and stage a phony funeral so that Calloway will back off. But then Calloway arrives at Boss' "funeral" to make sure his old enemy really is dead, forcing the Dukes to come up with another plan to foil the mobster's plans.

Coy falls for a shady motorcycle stunt driving woman who turns out to be one of the crooked cops hijackers that has been robbing people. When Vance finds this out, a fight between Coy and Vance has Coy leaving the farm.

The Russians' gymnast team comes to Hazzard and a defector named Natasha escapes and hides out at the Duke farm while Boss helps the Russian gymnast leader find her.

Uncle Jesse is blinded while trying to foil a robbery. But the robbers won't rest until Jesse's dead. So they go to Hazzard to track him down while Coy, Vance and Daisy decide to hide their sitting duck uncle at Boss' house.

Bo and Luke return to Hazzard after great season at the NASCAR Circuit and they won but they wanted to come home - which is ok since Coy and Vance have to leave Hazzard to take care of a sick relative. Meanwhile, Boss plans to foreclose on Cooter's garage - after Cooter owes a balloon mortgage payment - so he can put up a new shopping center.

Bo and Luke become big brothers to a young boy who steals the General Lee, hubcaps, etc. But Bo and Luke try and point him in the right direction. Meanwhile, Boss hasn't been eating lately because he hasn't found a crooked deal in quite some time.

Boss Hogg forecloses on the Duke farm and a bunch of other farms to sell the land to a big developer named L.S. Pritchard. But what he don't know is that she plans on using Hazzard to strip-mine coal.

Bo and Luke have been very over-protective towards Daisy ever since they've gotten back. So Daisy decides to move out for a while. But on the way, she is kidnapped by the son of a dirty moonshine dealer of Boss' and taken back to their place in the hills for a shotgun wedding.