Deadly explosives have been smuggled into U.S.A., from Mexico, via pastries. Mexican authorities seek help from Gene and Pat, who try to run down the smuggling outlaws. While Pat is busy trying to carry a birthday cake for Gene without tripping and falling into it, and a French baker, Mimi, Gene discovers evidence at a death sight of a Mexican official that point to the pastries. Pat carries a box with a cake in it that secretly holds explosives, Gene saves his friends, and brings Mimi and her gang in.

Gene, and his new parnter Tiny Jensen are riding into town to buy lumber, since their barn is destroyed in a storm. Gene befriends a young boy and his mistreated palamino. Gene and Tiny try to trail down bank robbers, who are at that moment planning to do another job. Gene and Tiny are able to find them, and bring them to justice.

Gene helps Doc Leary from a wagon hold up, not knowing that Doc staged the hold up. Later, the local marshal, Douglas Vance gets into a fight with his old enemy, Milo Miller. Doc then gives instuctions to Ennis, the leader of the holdup to kill Douglas and Milo. Before he kills Milo, Doc reveals his real name as Johnny MacClain. Milo is able to tell Douglas that he's next on the list. Milo's foreman, Hod Baker accuses Douglas of the murder and Gene arrests him. Gene found out that he and Milo had sentenced Johnny to death, but his sentence was commuted. Gene rides after the outlaws and captures Ennis. He and Pat, who is now practicing hypnotism and hypnotizes Johnny, who tells his real name, and goes to kill Douglas, but Gene catches him, and now he is behind bars, and Douglas is in front of bars.

Miss Nettie, who is the new self-acclaimed sheriff, jails Gene and Pat, accusing them of being counterfeiters. Gene sings, soothing Miss Nettie, allowing them to escape, to bring in the real counterfeiters, who have been acting like complete gentlemen around her. After they are brought in, Miss Nettie gives Gene and Pat a pardon, and jails the real counterfeiters, while at the same time, resigns as sheriff.

Gene and Pat deliver a letter to Ma Walker from her son Billy. He sends her mother $1.00 and an apology for not seeing her on Mother's Day. When Gene and Pat ride into town, they chase after some outlaws who have just robbed a bank. They capture one of the outlaws, only to find it's Billy! Billy promises to go to jail after visiting his mother. The next day, the Walt Brandy gang ambush Gene and Pat and take take Billy hostage. The sheriff assumes Gene and Pat let him loose, so they're arrested. Ma goes after Billy, and Gene and Pat break out of jail to go after her. She then pleads for Billy's release, but the gang aren't compling. Ma is shot when she shields Billy from being shot by one of the gang members. The sheriff and his posse arrive and free Billy.

Gene discovers dynamiting at a safe robbery. His number one clue is the fuse the outlaw used. Gene is confused when the fuse is times at 4 1/2 minutes to blow open a safe. Pat believes the fuse was that long so the robber would've had time to escape. Gene believes then that the dynamite was a cover up. Gene arrests his suspect, George Evans, who admits to lighting the dynamite, but to cover up the earlier disappearance of the money. Pat uses his new telescope to watch someone's hand at poker, Gene then believes the telescope could be used to find the combination to the safe. Gene sets a trap for the robber who he suspects to be Jim Lear, one of George's co-workers, by replacing the door of the safe and the combination. Gene is surprised to find the real outlaw is the hotel manager, John Turner. He and Jim are taken in.

Gene and Pat are called in to help Jim Saunders with his stageline troubles. Jim's son, Ray is in love with the daughter of Jason McKee, Linda, and ends up assisting Jason about the stageline information. Linda tells Ray to tell Jason that Gene is taking the payroll. Jason has his henchmen go out to capture Gene, only to find that he and Jim have switched places. Jim is captured, and Ray goes after him, and is followed by the outlaws, who are followed by Gene. The outlaws wound Ray during a gunfight with Gene, who captures the outlaws, and solves Jim's stageline troubles.

Social leader, Emma Conley, is secretly a trapeze artist with a touring carnival. Fearing her past will be revealed to her neighbors, she hires two gunmen to drive the carnival out of town. After Gene discovers Emma's secret, he tries to convince her that this is nothing to be ashamed of, but to be proud of. Emma then tries to fix the whole situation, only to find the gunmen are planning to rob the carnival. Gene sees right past this, and brings the two in, and Emma is now no longer ashamed of her hidden talent.

Gene returns from a trip, and meets a jockey named Billy Stone, who joins Gene. They find out that rancher, Sandy Dawson had hired some new farm-hands. Little does she know that the hands she hired are really rustlers in disguise. Billy discovers the stolen cattle, and runs away to the rancher to find the rustlers' belongings. Gene and Billy find the rustlers, and take them down. Afterwards, Billy is off the hook, but he decides to stay in Texas.

The Wild West is swathed in ribbon and silk when tailor, Pat Buttram is mistakenly sent a shipment of women's clothes. Burr Rasmsey, would-be town kingpin, wants to throw the quiet town wide open for gambling. He see his chance for putting Pat, whose shop is the last remaining building standing in the way of a casino, out of business. When the clothes are stolen, Gene Autry tricks Ramsey into proof of the robbery.

Jerry Miller becomes involved with a train robber, Vance Evans to receive a quick buck to support to his younger siblings, Sue and Bobby. When Jerry rides home, Vance's henchmen capture him to drop him in a hole. Gene and Pat save Jerry, and ride after the outlaws who are now after Sue and Bobby. Afterwards, Jerry convinces Gene he's not one of the outlaws. Gene then goes out to find more information. Sue warns him about the approaching outlaws, and Gene knocks them unconscious, only to find he's held up by Vance. Gene is forced to drive him and Bobby, who is now his hostage out of town, Gene drives the wagon, but then jumps into the buckboard, and brings Vance in.

Pat inherits a stage line from a distant relative. Gene and Pat head out west to pick it up. Gene runs into a crippled kid named Bonnie, whose father is away. When Gene starts to talk with her, he sees a masked outlaw who ambushes Pat. When Gene and Pat get to Rock River, Gene learns of a long dispute between the Buttrams and the Fords. Bonnie was a victim of the feud, with her uncle Jim Ford in jail, for shooting Terry Buttram. Gene looks for Lafe, her father, finding out that Big Mike is possing as him to get ahold of Pat's stage line. He and a partner pose as Fords, ambush and kill Pat! When they close in, Pat comes back to life, and he and Gene bring them in, settling the dispute between the Buttrams and the Fords.

Pat entertains Gene and Pat's boss, Lynne Moore's nephew, Johnny, by make believing a stage robbery. This cathces the attention of a gang of robbers, who then dress like Gene and Pat, fooling the town's citizens, and Johnny. Gene and Pat find themselves sandwiched between trying to elude the sheriff's posse, and trying to bring in the outlaws. With Johnny's help, Gene and Pat track down the outlaws, and Johnny learns a lesson in life that there's more to life than what meets the human eye.

While trailing through the west, Gene and Pat are shot by prospector, Thad Trigg, who thinks the two are outlaws who are wanting his newly discovered gold mine. Amelia, Thad's wife invites the two in. Thad then recognises his old friend, Gene, and explains that burgalars have been terrorizing the town, and is afraid one of them will come after his gold mine. Gene ad Pat ride into town to speak with the sheriff, though Pat is once again preoccupied with a cute hair salon owner. Little does Pat know, the salon owner, Corinne is behind all of the robberies. When Amelia comes in to have her hair and nails done, Corinne insists on making a house call, when Amelia shows her a gold nugget. Pat hears this, and tell Gene, who has been tipped about Corinne's mysterious pop-ups during robberies. Gene and Pat ride to the Triggs place, to find Thad unconscious, and the map to his mine stolen. After a chase, Gene and Pat capture the outlaws, while Amelia captures Corinne.

Gene and Pat are called in to bring in Mack Healy's gang of outlaws. Nate Tully is the town's gossip, and claims to not know a thing about the gang's whereabouts, but he is actually their ringleader. When Gene and Pat go to talk with Grandpa Dekker, he captures them, thinking their claimjumpers. His grandson lets them go though. Gene and Pat investigate Grandpa s mine, only to find they're almost ambushed by one of Mack's men. The outlaws capture Gene and the grandson, and knock grandpa unconscious. Amazingly, when Pat arrives, he is able to round up the outlaws and bring them in. As it turns out, Grandpa's mine is rich in copper.

Pat enters a chariot race at a local fair that's in town. Confident that Pat will win, Gene places a bet, using the budget of an old school that's funding for a new building. There's dirty playing as the champion chariotist sabatoges Pat's chariot. This doesn't go unnoticed by Gene, and insists that Pat trade chariots. Pat wins the race, and the school is on it's way to having a new building.

While riding through the west, Gene discovers Gold Dust Charlie had been murdered, and the culpret had just gotten away. Gene finds gold while burying Gold Dust Charlie, and is immedietaly arrested. Gene sneaks out of jail, and follows Harry Taylor, who was once Charlie's partner. Betty Taylor fires a shot, callinmg attention to the sheriff's posse, and Gene takes the Taylors in old mine, and sets a stick of dynamite. The sheriff arrives right when the killer gets away again. Gene saves the Taylors, and sends the killer to jail.

While out on a stroll through the countryside, Gene's boss is shot and killed. Gene teams up with newcomer, Pat Buttram to find out who the ambusher is. The leader of an outlaw gang imposses as Gene's co-workers niece, Debra Randall. It turns out that Gene's co-worker is part of the gang, and it was him who killed his boss. With the help (sort of) from Pat, Gene takes the outlaws in.

Gene and Pat are searching for a masked gang, when they find rancher, Mac Forbes, and old friend of Gene's is dying. He has willed his share of the rancer to his partner, Tom Lawton. After hearing this, Jeff Forbes, Mac's black sheep nephew tries to claim the ranch for himself. Jeff ambushed and killed Tom, but plays innocent to Gene. After Tom recovers from paralyzation, he tries to shoot Jeff. Gene allows Jeff to leave, who runs to his prartner in crime to kill Tom and claim the ranch. Gene follows and stops them in the nick of time.

New neighbors, the Townes arrive out west. Little Theodora (who is called Teddy by her father) hears about Gene Autry living around here. She runs away to find her cowboy hero. She tells him that she's homeless, so Gene takes her in. After her father finds her, Theodora tells him that Gene kidnapped her. Colonel Towne has Gene and Sagebrush arrested, but when Gene ends up in a dispute with an outlaw trying to own water rights, Theodora tells the truth, and Sagebrush washes her mouth out.

Pat is elected sheriff of Goose Creek, and makes Gene his deputy. Pat's job: to track down escaped convict, Red Lambert, who is is heading towards Goose Creek. Gene and Pat head out through the countryside, but when Pat falls behinds, he runs into Red, who forces him to switch outfits. Red, wearing Pat's outfit ambushes Gene and takes his guns. Gene then finds Pat in a black and white striped outfit. They head to Hiram Glover's ranch for guns. Gene and Pat find themselves trapped by Hiram and his daughter (who Pat of course has a crush on). The Glovers are helping Red out, who's trying to prove he's innocent. Gene and Pat are able to escape, and find evidence that Brad Bidwell, who hired Pat, was the killer of the former sheriff.

Pat and his wagon passenger, Diana Jamison are attacked by two men, who plan to abduct Diana, but Gene is able to foil their plans. Steve Kinney tries to scare Diana's father, Dave into selling his ranch to have two ranches linked togethe across the border to smuggle good. Steve tries to ambush Dave, but is unsuccessful, and Gene is able to apprehend one of his outlaw members. The two men, then attack Dave's ranch and kidnap Diana. Gne chases after them, only able to apprehend on of them. Gene and Pat plan a sneak attack, by smoking the outlaws out, while Pat rescues Diana. Steve meanwhile forces Dave to sign an agreement, but Gene arrives to save the day, and brings Steve in.

Gene,Pat, and a young woman named Lita are on their way to deliver a shipment of gold bars, worth a quarter of a million dollars. A gang of outlaws lead by Duke Travis attack them, but get away when Gene rescues Lita. Gene then goes after the outlaws, who have headed to Ghost Town. Gene then contacts law agencies in order to track down the goldbars, which are found at the Mexican border, being sold as nuggets. Gene, Pat, and the Mexican officials ride down to Duke's mine, only to find that it hasn't produced gold nuggets in years. Gene traces the gold back to Ghost Town that are being sold is horseshoes with an iron shell to hide them. Gene recovers the gold, takes Duke's gang in, and Pat claims he's seen a ghost.

Jud Halsey, the editor and publisher of The Tribune newspaper, prints headlines of crimes before they actually happen. His newest headline reads ""Gold Stage Robbed-Sheriff Killed"", and has his son, Burke in charge of carrying it out. Jud hopes that Burke will be promoted to sheriff, which will mean they'll get to run the town. Burke kills the sheriff, but Gene and Pat stop the gold robbery. With that, Gene is named sheriff, although Jud and Burke protest. Burke brings in his henchman, Pete, who knocks Gene unconscious, but that doesn't stop him from continuing his job as sheriff. The next headline reads ""Stage Robbed Again-Autry killed"". Pat notices this headline, and rides after Gene, who is accompaning the stage. Pat saves Gene's life, and Jud and Burke are arrested.

Two masked outlaws rob a buckboard driver of his silver bars. Gene rides after the outlaws, while Pat aids the driver. When Gene has one of the men cornered, the other knockes him unconscious. Gene recovers with a bad headache, and Pat breaks the news that the driver is dead. They find out that he was carrying silver, and visit the sheriff, who explains that this is the fourth robbery in a row. Gene gives Dorrie Taylor, a new townsperson to her Uncle's ranch, when they discover a masked outlaws killing another stage driver, who is Dorrie's uncle. Gene drops Dorrie off at her uncle's ranch, not knowing that their housekeeper, Ada Mitchell is the ringleader of a counterfeiting gang. Dorrie is kidnapped, and Gene and Pat ride after her. Gene is ambushed by the gang, but he brings them down, and takes them in, and Ada Mitchell, and is able to save Dorrie.