The Nutrient Bath has left Rick Jones transformed into a rampaging teenage Hulk and Bruce turning into a Gray Hulk. Bruce now faces a charge of attempted murder and his lawyer is Jennifer Walters (aka She-Hulk). Meanwhile, The Leader has a plan to capture Rick Jones and suppress Bruce's mind within Gray Hulk.

A dark entity enters our dimension and takes over Bruce's body. She-Hulk gets help in the form of Dr. Strange, who enters Bruce's mind to convince the Gray and Green Hulks to work together against this dark entity.

Gray Hulk and She-Hulk have to work Agent Jones and S.H.I.E.L.D. to save the Sea Base's unstable Gamma Power Core.

During her high school reunion, Jennifer admits she is becoming unhappy about being She-Hulk. As Bruce sees what he can do to help, The Leader and Gargoyle plot to capture him.

Miss Allure and Crusher Creel are making Chicago's crime world an even nastier place. To stop them, She-Hulk masquerades as a mob boss while Gray Hulk dons a pin-stripe suit, becoming Mr. Fixit.

Bruce and She-Hulk search for the mythical valley of Anavrin in Tibet, where they believe Bruce can be cured once and for all.

Bruce has to stop asteroids from colliding with Earth, but his equipment is stolen by the Fantastic Four's arch-nemesis, Doctor Doom. While Green Hulk storms off after him, She-Hulk is on the fast track to becoming a tv star.

She-Hulk is taking part in a Miami fashion show for charity, when The Leader and Gargoyle attack. It's up to She-Hulk, Betty and a group of models to stop them.