High school sweethearts Lisa and Jimmy Moore end their marriage, and Lisa goes missing three months later; fearing the worst, her family files a missing person report, but the police have no leads and no witnesses.

After Louisiana Melton and her boyfriend, Phillip Brown, are found shot to death, Detective Harris faces a dearth of evidence, a large list of suspects and one huge lie.

In Feb. 24, 1996, school bus company owner Frank Black Jr. goes missing; FBI agents must determine if he's dead; it's a mystery built on lies that can only be solved when someone is brave enough to tell the truth.

In 2006, Angela Ferguson tells police her husband left during an argument and hasn't been seen since. When his body is found in a car boot, it becomes a murder case.

Pastor David Allen loses his wife, Paula, in a fire at the parsonage; the fire marshal investigates and discovers there is more to this story than an accidental fire.

In 2014 a 911 call reports gunshots at the home of TV Host, Scott Rogers. As detectives work to piece together the events that led up to what looks like a murder-suicide, they soon discover a trail of lies from England all the way to Louisiana.

On Aug., 10, 2000, Casey Tiner and her boyfriend, TJ Steele, disappear after spending a summer night hanging out with their friends, causing people to speculate they may have simply run away.

Karla leaves her home one night and never returns; the next day, her husband calls the police to file a missing person report; when the police uncover a treasure trove of hidden secrets, they have to decide who is lying.