Tom is the pet of a team of superheroes, the Amazing Acquaintances (a parody of Power Rangers), charged with guarding their power rings. However, when Jerry gets into the room where the rings are kept, he and Tom end up having a super-powered duel. To make matters worse, Doomdog (Spike), the Acquaintances' arch-enemy, breaks into the hideout unnoticed and wants all the rings for himself. Tom and Jerry have to work together—pooling their powers of fire and ice—to take the villain down. The heroes congratulate Tom on the capture of Doomdog, but Jerry—with the help of a growth-powered ring—reminds him not-so-gently that he didn't exactly do it alone.

Jerry is zapped by a speed ray, making him faster-than-ever.

Tom and Jerry fall into a garden hole where they find a basement headquarter.

Buddhist monk Tom tries to achieve inner peace.

Spike, as a genie, must grant wishes.

Tom must obtain a mouse for a witch's potion.

Tom attends show-and-tell at school. Nancy from 1943 cartoon Baby Puss returns, as she wants to win the gold star for best pet.

Jerry and Tuffy try to ruin Tom's chances at a cat show.

Tom's owner hires a trainer to make him behave.

Jerry and an escaped penguin become friends.

Tom, who is hungry, seeks to catch and eat Jerry, who is the star of the show at a local ocean theme park along with an eagle, but he is thwarted by the eagle, a seal and an octopus.

Jerry makes friends with a baby rhinoceros.

A green shapeshifter emerges from an alien spaceship that lands near Tom and Jerry's house.

Van Helsing, the famous legendary monster hunter, and his assistant, Tom, stop at a hotel, where a Monster Convention is taking place. While there, the cat uses some of Van Helsing's equipment to try to catch Jerry, but he catches a few ghosts instead. Later, Tom gets bitten by a werewolf and transforms into a panther, which makes him a target for Van Helsing, who mistakes him for a werewolf cat and seeks to add him to his collection.

Tom and Jerry get lost in a haunted forest where Butch, as a bat (with the same size as Tom) , tells them that only one of them can escape. Butch uses this chance to escape, while Tom and Jerry try to outrun him to the exit.

Jerry dresses up like a skateboarder in an effort to get food from the refrigerator. Afterward, he pursues a truck with a shipment of cheese with Tom hot on his trail on a dirtbike with hijinks to follow.

Tom competes against Droopy as a role for lifeguard at the local pool.

Whilst on a camping trip, Tom, Jerry and Tuffy come across the legendary sasquatch - who happens to be a big-footed, short but friendly creature named Sheldon.

Mrs. Two Shoes assigns Tom to keep all the pests, which includes Jerry, out of the garden, but the job gets pretty complicated for the cat as Jerry has a number of lookalikes with him (they all wear different coloured bandanas).

Butch invites Tom to join the League of Cats, a secret organization that believes in a more effective way of catching mice by ganging up against them. Jerry counters by organizing a League of Mice to outnumber the cats.

During a brutal heatwave, while Tom and his ower, Mrs. Two Shoes, are relaxing by the refrigerator, Jerry takes all the food for a picnic which leaves the cat to take the rap for the thefts-and get expelled from the house. Tom manages to retaliate with a help of an ant.

Tom's emphatic soccer playing annoys Spike and Jerry. Look for a cameo from the hawk from "Flirty Birdy" and an homage to the classic leash gag from "Fit to Be Tied".

Tom, Jerry, and Droopy enter a surfing competition. To everyone's surprise, Droopy wins for the big cash prize. Tom narrowly beats Jerry for second place and wins a lifetime supply of cheese!

Tennis champ Tom tries to teach Tyke the game, at his father's behest. But, he was tired and lots of disasters happened. When Tom uses a ball thrower. Jerry turns it to fast and the balls goes to Tom and he hits all. Until the last ball pops out, it hits Tyke's nose, causing him to cry and his father turns Tom into a tennis racket. Then, Jerry ties a racket in Tyke's tail and Tyke hits the ball and his father takes a last shot and he misses the ball. Spike's glad that his son has skills and turns Tom into a ball and they play all time.

Just after Thomas Jefferson writes the Declaration of Independence on July 4, 1776, Tom proceeds to lose it by making it into a paper airplane when throwing Jerry out of the house. Jefferson sends the cat out to retrieve it, but as usual, the mouse and Redcoat dog Spike make the task difficult for him.