A blindfolded taste experiment tests the chefs. Later, the chefs draw inspiration from their own childhood memories to create meals for a charity gala for the MUSC Shawn Jenkins Children's Hospital. Appearing: Michael Voltaggio and Graham Elliot.

The three remaining chefs head to the Yucatan Peninsula where Chef Roberto Muñoz Zurita challenges them to make a dish showcasing the flavor, complexity and heat of the legendary local habanero using ingredients from the local market. Culinary legend Jeremiah Tower gives the chefs a lesson on traditional Mayan cooking, before challenging them to create a dish using only ancient Maya ingredients and tools. The chefs will cook in an ancient cenote, or sinkhole, for a table of judges including local chefs Roberto Solis, Guillermo Beristain and Carlo Cardenas. The two chefs with the best dishes will move on to compete in the finale.

The chefs divide into teams to compete in a "mise en place" race. The foodies must also create a seven-course progressive meal featuring the humble radish in front of "Top Chef" superfans. The guest judges are Chris Cosentino and Richard Blais.

The iconic Restaurant Wars challenge features the chefs dividing into teams to design a restaurant and create a cohesive menu, but the heat is on when egos collide and tempers flare. Appearing: chef Daniel Humm and restaurateur Will Guidara.

The final four chefs cook impromptu dishes while simultaneously instructing mystery partners on how to create the same dish; when the judges compare dishes, the chefs are shocked to discover their secret partners are their visiting family members.

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U.S. Surgeon General Vivek Murthy enlists the chefs to create vegetarian versions of traditional comfort foods. Then, the chefs must prepare dishes that pay tribute to Edna Lewis, the matriarch of Southern cuisine. Appearing: Alexander Smalls; Art Smith; Hugh Acheson; Nathalie Dupree; and Mashama Bailey.

In Guadalajara, Mexico, the three remaining chefs face off against the winner of "Last Chance Kitchen'. The chefs must create a dish using goat, then they are tasked to pair their own cocktail with a dish that incorporates the notes of a margarita.

The chefs join the judges for a traditional shrimp boil; the newcomers face off against the returning chefs to put a spin on a low-country family meal; after dining with chefs Carrie Morey and BJ Dennis, each team creates a family-style feast.

The chefs must create dishes using an odd mix of ingredients and tools found inside gift boxes. Later, they prepare a traditional Italian-American seafood-filled dinner, but they're forced to use a notoriously undesirable fish species. Appearing: editor Nilou Motamed and foodie Mike Lata.

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The chefs are asked to prepare a decadent brunch for the famed Charleston Hat Ladies. However, it won't be a traditional southern brunch as they must create whimsical breakfast and lunch hybrid dishes inventive enough to impress the judges.

Ingredients and the element of the chefs' zodiac sign must correspond. Later, the food fighters divide into teams to throw a pirate-themed bash, during which they must race through Charleston in a treasure hunt to collect their ingredients. Appearing: Michael Cimarusti and Graham Elliot.

The final two chefs face-off to serve the best meal of their lives and earn the coveted title of Top Chef. The finalists will cook an epic four-course progressive meal with the help of three sous chefs, comprised of two eliminated chefs and one from their restaurants back home. The pressure is on as only one chef can win. The chefs must impress a dining room filled with their families, returning judges Graham Elliot and Gail Simmons, and distinguished chefs Joachim Splichal, Jonathan Waxman, Martha Ortiz, Jonathan Sawyer, Daniel Boulud and FOOD & WINE's Nilou Motamed.