As heroin devastates the streets of 1970s New York, DEA agents team with Thai authorities to bring down Khun Sa, the criminal mastermind controlling 70% of Burma’s global drug trafficking trade.

After thirteen sailors are executed on a ship along the Mekong River, a Chinese task force is granted special permission to lead a manhunt across the Golden Triangle for suspected kingpin and merciless water taxman Naw Kham.

As a meth epidemic sweeps through the Golden Triangle, police investigate the operation’s rumored leader, Xaysana Keopimpha, but find themselves at the mercy of complex hierarchies within the syndicate.