The Sistas must put their current individual problems and traumas aside when they learn something is wrong with Karen's pregnancy; it's a mad dash to the hospital in a city recovering from a blackout.

With Karen's suffering being ignored by a dismissive doctor, desperation sets in as the Sistas search for a doctor who cares; when Karen receives the needed attention, a shocking discovery is made.

A fed-up Sabrina takes control of her life and goes searching for direction on the wild side; Andi discovers deep, dark secrets during her deep dive into Dr. Cruise.

Despite best efforts, Karen refuses any kind of comforting company while the rest of the Sistas confront their own individual problems as they all rear their ugly heads again.

As Sabrina confronts her betrayers and Andi digs into a grave case, Karen sinks deeper into postpartum struggles; Danni, Fatima, and Zac face unexpected turns that test their limits.