Comedians Rhod Gilbert and Greg Davies attempt to drive through the mountainous, landlocked nation of Nepal.

Ben Fogle and Hugh Dennis travel from the Peruvian Andes to the depths of the Amazon, in search of the lost city of Constitucion.

Comedian Sue Perkins and adventurer Charley Boorman travel across Alaska to the notorious Dalton Highway - a dirt track built in the 1970s as a supply road to support the Trans-Alaska oil pipeline. Highway maintenance is a full time job here with avalanche units operating throughout the year. As Arctic conditions close in on them, the pair have to rely on the help of hardcore truckers for whom the highway is home. The rules of the road are: keep the CB radio switched on, don't exceed 50mph, and when an 18-wheel truck comes thundering down the rollercoaster of a road towards you, get out of the way!