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The Best Episodes of A.P. Bio

Every episode of A.P. Bio ranked from best to worst. Let's dive into the Best Episodes of A.P. Bio!

Binge this in 15h 24m•Peaking at 9.5/10

When disgraced Harvard philosophy scholar Jack Griffin loses out on his dream job, he is forced to return to Toledo, Ohio, and work as a high school Advanced Placement biology teacher.

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Episode Rankings

  1. #1 Fan Favorite
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    A.P. Bio Season 2 Episode 10 - Handcuffed
    9.5/10(311 votes)

    #1 - Handcuffed

    S2:E10

    When he's kicked off his Harvard phone plan, Jack is offered a chance to leapfrog onto Mary's on one condition: He helps her break up with her scuzzy boyfriend. Meanwhile, Anthony becomes Durbin's right-hand man.

    Director:Jennifer Arnold
    Writer:Paula Pell

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  2. A.P. Bio Season 2 Episode 4 - Toledo's Top 100
    9.0/10(354 votes)

    #2 - Toledo's Top 100

    S2:E4

    Jack is aghast to learn he didn't make the Top 10 in Toledo's Top 100 Bachelors, and Durbin did. Victor and Eduardo decide it's time to reveal their feelings to their crushes.

    Director:Maggie Carey
    Writer:Emily Cutler

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  3. A.P. Bio Season 2 Episode 7 - Personal Everest
    9.0/10(341 votes)

    #3 - Personal Everest

    S2:E7

    Jack is outraged when his old high school bully is hired as a motivational speaker at Whitlock. Mary, Stef and Michelle set their own personal goals of female empowerment, unintentionally causing a rift between Helen and Durbin.

    Directors:Payman Benz, Andrew DeYoung
    Writer:Shelly Gossman

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  4. A.P. Bio Season 2 Episode 12 - Ride the Ram
    9.0/10(296 votes)

    #4 - Ride the Ram

    S2:E12

    It's the most exciting time of the year at Whitlock: Durbin's birthday and Spirit Week. Jack does his best to steer clear of any school spirit as everyone else comes together to take down their hated rivals at Prairie High.

    Director:Michael Patrick O'Brien
    Writers:Michael Patrick O'Brien, John Solomon

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  5. A.P. Bio Season 4 Episode 2 - Sweatpants
    9.0/10(261 votes)

    #5 - Sweatpants

    S4:E2

    Jack has the students form a fake cult to sabotage Principal Durbin's new school uniforms.

    Director:Katie Locke O'Brien
    Writer:Rob Klein

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  6. A.P. Bio Season 3 Episode 6 - That That That
    8.5/10(388 votes)

    #6 - That That That

    S3:E6

    As the school prepares for winter break, Jack tries to record a lecture on Thoreau's transcendentalism as a way into the University of Wisconsin's philosophy department. Frustrated and unable to finish the video, he falls asleep and has nightmares.

    Director:Richie Keen
    Writer:Charlie McCrackin

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    The 20 WORST Episodes of A.P. Bio

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  7. A.P. Bio Season 1 Episode 9 - Rosemary's Boyfriend
    8.2/10(473 votes)

    #7 - Rosemary's Boyfriend

    S1:E9

    Jack is incensed when his dead mom's former lover shows up and suggests they commemorate her birthday. Jack taps his students to help him retaliate, but the students' hands are already full - of crying robot babies. Stef's kindness toward Dale the janitor sends the wrong signals.

    Director:Maggie Carey
    Writers:Michael Patrick O'Brien, Charlie McCrackin

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  8. A.P. Bio Season 1 Episode 6 - Freakin' Enamored
    8.0/10(515 votes)

    #8 - Freakin' Enamored

    S1:E6

    When Jack is attracted to a student's mother at a parent-teacher conference, he feigns interest in her son; a group of parents complain to principal Durbin when they notice a piece of controversial student art from Mary's class.

    Director:Oz Rodríguez
    Writer:Shelly Gossman

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  9. A.P. Bio Season 1 Episode 11 - Eight Pigs and a Rat
    8.0/10(496 votes)

    #9 - Eight Pigs and a Rat

    S1:E11

    When one of Jack's students anonymously reports him for canceling their much-anticipated fetal pig dissection, he sets out to find the snitch. Durbin's chances at Principal of the Year are in jeopardy when the superintendent visits.

    Director:Carrie Brownstein
    Writers:Michael Patrick O'Brien, Zeke Nicholson

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  10. A.P. Bio Season 2 Episode 3 - Wednesday Morning, 8AM
    8.0/10(481 votes)

    #10 - Wednesday Morning, 8AM

    S2:E3

    In the hectic thirty minutes that start every day at Whitlock, Jack tries to retrieve his massage chair from Whitlock's intriguing payroll accountant, Lynette. Durbin and Helen prepare for the morning announcements. Michelle gives a eulogy.

    Director:John Solomon
    Writer:Michael Patrick O'Brien

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  11. A.P. Bio Season 2 Episode 5 - J'Accuse
    8.0/10(365 votes)

    #11 - J'Accuse

    S2:E5

    Jack uses Michelle's annual murder mystery party to impress Lynette. Meanwhile, in a moment of desperation, the students break into Whitlock High to steal the A.P. Bio practice exams.

    Director:Andrew DeYoung
    Writers:Michael Patrick O'Brien, Charlie McCrackin

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  12. A.P. Bio Season 2 Episode 6 - Melvin
    8.0/10(381 votes)

    #12 - Melvin

    S2:E6

    Jack's war with his neighbor reaches a turning point when it threatens to ruin a date with Lynette. When the school photographer ups his rate, Durbin takes school pictures into his own hands.

    Director:Katie Locke O'Brien
    Writer:Dan Klein

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  13. A.P. Bio Season 2 Episode 8 - Sweet Low Road
    8.0/10(337 votes)

    #13 - Sweet Low Road

    S2:E8

    When budget cuts threaten to gut Whitlock and put his job in jeopardy, Jack recruits Mary, Stef, and Michelle to take down the Superintendent. Durbin plans an appeal to the heart, while the students plan an appeal to the soul.

    Director:Richie Keen
    Writers:Donick Cary, Emily Cutler

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  14. A.P. Bio Season 2 Episode 9 - Dr. Whoopsie
    8.0/10(346 votes)

    #14 - Dr. Whoopsie

    S2:E9

    After an embarrassing video of him falling off a stage goes viral, Jack plans a viral video of his own. Durbin, Helen and the teachers track down Whitlock's most notorious litterer: The Sugar Daddy.

    Director:Blake McClure
    Writers:Michael Patrick O'Brien, Rob Klein

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  15. A.P. Bio Season 2 Episode 11 - Spectacle
    8.0/10(311 votes)

    #15 - Spectacle

    S2:E11

    After his computer breaks, Jack rallies his class to win the annual Whitlock's Got Talent competition so the prize money can go towards a new laptop. Helen and Durbin put on their best tuxes to host while Mary, Stef and Michelle prepare a hand-bell routine.

    Director:Carrie Brownstein
    Writer:Amy Hubbs

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  16. A.P. Bio Season 2 Episode 13 - Kinda Sorta
    8.0/10(336 votes)

    #16 - Kinda Sorta

    S2:E13

    The college fair comes to Whitlock, and Sarika has an offer to Jack: Get her into Harvard, and she’ll get his book into the hands of her publisher aunt. Meanwhile, Stef prepares for a visit from a fling, Helen applies to college, and Durbin tries to cement his legacy. Season finale.

    Director:Trent O'Donnell
    Writer:Unknown

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  17. A.P. Bio Season 3 Episode 2 - Disgraced
    8.0/10(290 votes)

    #17 - Disgraced

    S3:E2

    Mr. Pugh plans a field trip for the Toledo chapter of the Ohio Naturalists. When Jack can't write his own book, he agrees to be ghostwrite for popular author Robin Shwank -- only to insert his own chapters into Shwank's book.

    Director:Oz Rodríguez
    Writer:Shelly Gossman

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  18. A.P. Bio Season 4 Episode 3 - An Oath to Rusty
    8.0/10(228 votes)

    #18 - An Oath to Rusty

    S4:E3

    Jack attempts to get closer with the guys at work. Helen helps Principal Durbin grow a backbone.

    Director:Katie Locke O'Brien
    Writer:Shelly Gossman

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  19. A.P. Bio Season 4 Episode 4 - Tons of Rue
    8.0/10(237 votes)

    #19 - Tons of Rue

    S4:E4

    Jack tries to expose his allegedly reformed deadbeat dad. A witch shakes up the Whitlock High staff.

    Director:Unknown
    Writer:Unknown

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  20. A.P. Bio Season 4 Episode 5 - The Perfect Date From Hell
    8.0/10(224 votes)

    #20 - The Perfect Date From Hell

    S4:E5

    Jack finds out he's his girlfriend's therapy homework. Principal Durbin goes undercover.

    Director:Unknown
    Writer:Unknown

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  21. A.P. Bio Season 1 Episode 12 - Walleye
    7.7/10(428 votes)

    #21 - Walleye

    S1:E12

    Jack successfully convinces Miles that Devin is his illegitimate son; Durbin, Mary, Stef and Michelle clash on the Sadie Hawkins dance theme.

    Director:Tristram Shapeero
    Writers:Michael Patrick O'Brien, Britt Matt

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  22. A.P. Bio Season 2 Episode 2 - Nuns
    7.5/10(418 votes)

    #22 - Nuns

    S2:E2

    As the newly minted driver's education teacher, Jack sets out to get revenge on his mother's church when he discovers the last of her money was used to buy a statue of the Virgin Mary.

    Director:Lynn Shelton
    Writers:John Blickstead, Trey Kollmer

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  23. A.P. Bio Season 3 Episode 5 - Mr. Pistachio
    7.5/10(275 votes)

    #23 - Mr. Pistachio

    S3:E5

    Jack has Mary drive him to the doctor, but a prank results in him getting the same procedure twice. At school, Durbin and Helen embarrass themselves and the kids compete over class superlative titles.

    Director:Oz Rodríguez
    Writer:Gilli Nissim

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  24. A.P. Bio Season 4 Episode 6 - Love, for Lack of a Better Term
    7.5/10(269 votes)

    #24 - Love, for Lack of a Better Term

    S4:E6

    Victor sends Ashlanda a risqué photo. Grace and Anthony try to set up Mary and Principal Durbin.

    Director:Unknown
    Writer:Unknown

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  25. A.P. Bio Season 1 Episode 5 - Dating Toledoans
    7.3/10(543 votes)

    #25 - Dating Toledoans

    S1:E5

    Jack reluctantly agrees to go out on the town with Mary, Stef, and Michelle; his superiority complex proves difficult for the women to overcome; principal Durbin feels threatened when Helen fills in for him on the school's morning announcements.

    Director:Ryan Case
    Writer:Aseem Batra

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Best Episodes Summary

"Handcuffed" is the best rated episode of "A.P. Bio". It scored 9.5/10 based on 311 votes. Directed by Jennifer Arnold and written by Paula Pell, it aired on 5/30/2019. This episode scored 0.5 points higher than the second highest rated, "Toledo's Top 100".