When Jack gets into a petty dispute with the student council president, the situation escalates much too far; Stef sells makeup at school as a side business.

Jack Griffin is a Harvard philosophy scholar who loses out on his dream job and goes to work as a high school Advanced Placement biology teacher in his hometown of Toledo, Ohio. He quickly makes it clear he will not be teaching any biology, however, and, realizing he has a room full of overachieving honor roll students at his disposal, decides instead to use the kids to enact revenge on his rival and take the job that is rightfully his.

When Jack leaves his class unattended, a student injury sets off an official investigation and lands Jack in "teacher jail." An aggressive teacher's union rep sets her sights on Principal Durbin. The students' excitement for a substitute teacher are dashed when they find out it's Helen.

With no archrival to combat, Jack sets his sights on a new mission: write the most brilliant philosophy book ever and get out of Toledo for good. Stef and Mary forget a special day for Michele. Helen forgets to order routine maintenance for the copier causing mass hysteria at Whitlock.

Principal Durbin takes it upon himself to help Jack advance his book with an appearance on Toledo's morning TV show but lets his five minutes of fame get the best of him. The other teachers lead a competition within the Young Entrepreneurs Club.

Jack has Mary drive him to the doctor, but a prank results in him getting the same procedure twice. At school, Durbin and Helen embarrass themselves and the kids compete over class superlative titles.

A jealous Jack crashes his girlfriend's dinner with a male friend. Helen rebounds after a breakup.

While Principal Durbin struggles with budget cuts, Jack discovers his students pity him - so he rallies, making a splash at the school bake sale and getting kicked out of the bookstore for life.

Jack reluctantly agrees to go out on the town with Mary, Stef, and Michelle; his superiority complex proves difficult for the women to overcome; principal Durbin feels threatened when Helen fills in for him on the school's morning announcements.

Jack attempts to get closer with the guys at work. Helen helps Principal Durbin grow a backbone.

Victor sends Ashlanda a risqué photo. Grace and Anthony try to set up Mary and Principal Durbin.

When Jack casually gives Durbin some marriage advice, it backfires, gets Durbin kicked out of the house, and Jack takes him in. The A.P. Bio kids tell Jack if they can get Miles' DNA, they'll learn a little biology while pulling off the ultimate revenge.

Principal Durbin and Helen sweep lockers. Jack finds out that Anthony has been lying about his extracurricular activities. Jack and Lynette follow Anthony to find out what he's really been up to. The search for Stef's baby donor intensifies.

A tornado puts the school on lockdown. The kids write fan fiction about faculty members.

Jack receives an offer from Miles' publisher to write a book of feel-good philosophy that could be his ticket out of Toledo. Durbin accidentally sets off an emotional firestorm when he reveals that while Stef chose Mary as her emergency contact, Mary chose Michelle.

Jack finds out his ex-girlfriend Meredith needs a venue for a charity fundraiser and has the perfect place: his student Victor's house. Victor and the other kids are inspired by Jack to party for the first time.

Jack takes interest in a revenge mission on behalf of the kids; Mary, Stef and Michelle believe they've discovered an otherworldly presence.

As the newly minted driver's education teacher, Jack sets out to get revenge on his mother's church when he discovers the last of her money was used to buy a statue of the Virgin Mary.

When Jack is disappointed with the popcorn maker he orders, he and the students plot revenge. Helen goes back to school to get her high school degree and chaos ensues in Principal Durbin's office in her absence.

Mr. Pugh plans a field trip for the Toledo chapter of the Ohio Naturalists. When Jack can't write his own book, he agrees to be ghostwrite for popular author Robin Shwank -- only to insert his own chapters into Shwank's book.

Jack finds out he's his girlfriend's therapy homework. Principal Durbin goes undercover.

Jack successfully convinces Miles that Devin is his illegitimate son; Durbin, Mary, Stef and Michelle clash on the Sadie Hawkins dance theme.

Jack tries to expose his allegedly reformed deadbeat dad. A witch shakes up the Whitlock High staff.

Jack accidentally loses a significant amount of money and it falls in the hands of the students. As Principal Durbin and Helen investigate who stole the money, the students and teachers admit to other wrongdoings.

Jack has the students form a fake cult to sabotage Principal Durbin's new school uniforms.