Malloy teases Reed about calculating the cost of a new house while their first baby is still 6 months away. In the meantime they settle a domestic dispute between arguing neighbors, help a taxi driver that was just robbed, and a local man mistaken as the President by a group of rural Mexicans. Finally, they must arrest a psychotic shooter holed up in his house.

Not long after an elderly woman insists that Reed and Malloy help adjust her television antenna, the officers are called to a high-rise hotel, where a suicidal man is determined to jump. Malloy incorrectly handles the situation and Mac harshly reprimands him the follow-up investigation.

On their day off, Malloy and Reed agree to give a talk to a group of fifth grade students, and then offer to let the kids watch them train for the California Police Olympics. But when the tires of their patrol car are slashed and a stopwatch goes missing out of reed's car, the two officers start to suspect one of the children.

Malloy and Reed investigate the death of an old man wearing an unusual belt, which leads to the case being turned over to Frauds Division, who finds that Dr. Gantman, running a clinic, is treating a blind seven-year-old patient with a pituitary gland condition but his "treatment" is worthless and preventing a real treatment (removal of the gland). Later, a TV repairman who makes oscillator belts for Gantman is busted for bookmaking and agrees to testify against the doctor, but Gantman demonstrates his "treatment" in open court and fails miserably. Note: This episode, in which Reed and Malloy appear only briefly, was intended to be the pilot for a new Mark VII series focusing on the Los Angeles District Attorney's Office, and was directed by Webb himself. However, no such series came to be.

Reed volunteers to line up entertainment for the department party, just as Malloy needs to serve a subpoena on a famous singer. The team learns of a drug den from their informant and are handed the bust when detectives are too busy to look into it.

Malloy and Reed work to curtail the rise in illegal street racing by working with the leaders of rival racing clubs and obtaining the legitimate use of a drag strip through a race promoter. Their work is threatened, along with an anticipated race between Reed and Officer Wells, when one of the racers resorts to sabotage.

Officers Malloy and Reed look for a robbery suspect, help a woman pinned under her crashed car and settle a family dispute, among other duties.

A ditzy young woman reports her 1958 Ford convertible stolen while she went into a liquor store. She left the keys in the car, has no paperwork, doesn't know the license number or other details but she needs it by 6 PM for a date. She finally tells the officers that her eight-foot boa constrictor is in the trunk as she was coming from the vet.

While Malloy is attending college, radicals learn he is a cop. They reject him and antagonize him on the job. After helping arrest demonstrators, his new car is vandalized. When a timer is found missing, he locates and disarms a bomb using it.

Reed hears a joke from Ed Wells before roll call, and then spends the shift retelling it to Malloy. The partners solve a mystery for a little old lady. Later, Reed needs to break up a noisy party hosted by an old school chum.

Malloy and reed hunt down a suspect who has been bombing downtown storefronts. Then they report to a scuffle between two native americans at a bar that the bartender thinks may be a prelude to something a lot more serious.

In an episode where Reed learns to keep his wits under control, the officers deal with a loud noise complaint where an elderly woman refuses to answer, much less acknowledge, a teenaged girl's desperate pleas for help after the woman learns she was at a house where loud party music is being played, and it leads to a tragic drowning of a 4-year-old girl in a backyard swimming pool. Other calls include a brawl at a pop-spirituality temple on the verge of a schism over meditation styles, and a misused silent alarm at a liquor store.

Reed tries to pawn off his new litter of puppies to co-workers, strangers, even victims. The officers work a silent alarm, rescue a boy with his head stuck in a fence, and track down a prowler.

Officer Reed loses a robbery suspect while in foot pursuit. Afterward, he and Malloy try to help a priest prevent bloodshed between rival hispanic gangs, and then respond to a battered wife whose husband is very familiar to the officers.

Officers Malloy and Reed assist a young mother whose baby is threatened by a deranged man and they help a woman being harassed by a spiteful neighbor. Reed worries all evening that the small dent in the fender he caused while backing the car up for fuel might lead to termination, since he is still on probation.

Officers Malloy and Reed are involved in a high speed chase, a murder case and a family dispute as they work the P.M. watch. Reed expresses frustration at turning a case over to detectives instead of investigating it.

Malloy and Reed respond to a call about a drug overdose and track the drugs to a 17-year-old who has barricaded himself in his room with a gun and threatens kill himself. They contend with a distraught mother and an overbearing father.

Reed's wife is in the hospital expecting their first child, and Reed soon regrets his decision to report for work as usual. Out on patrol, they encounter a drunken man directing traffic, chase down a robbery suspect, investigate the theft of money from washing machines and become involved in a minor traffic accident that results in a major delay.

Malloy and Reed track down a kooky female shoplifter involved in a cult-type relationship with a ego-maniacal spiritualist weirdo. Malloy gets help tracking her down from an old girlfriend.

Malloy and Reed investigate an extortion racket against a group of Jewish Holocaust survivors, with the owner of a dry cleaners willing to testify but others not out of fear of retribution. The officers return to handle the owner's panel truck being set ablaze and later the owner is physically assaulted. Malloy and Reed capture both suspects. Other incidents involved a robbery at a bar (the perps escaped initially, but are later captured after a shootout), and a drunk man owed back pay by a dockmaster threatens to dump his boat onto dry land from a crane unless he's paid.

A series of purse snatchings involving motorcyclists frustrates the LAPD, as they cannot follow them down the off-road trails they take. Reed holds a community meeting with the various motorcycle clubs, and the leader of one club challenges Malloy to a dirt bike race. Reed teaches Malloy how to ride a dirt bike, and while Malloy loses the race, he gains the respect of the club's leader, who helps them apprehend the suspects by blocking their escape route.

Pilot Episode: Working out of a patrol car designated "Adam-12," Officers Malloy and Reed perform a typical day's work, which includes a high speed auto-chase, the capture of two robbers, and an emergency call to save a suffocating baby. Malloy decides to turn in his badge after his young partner was killed a few weeks earlier. But at the end of the shift, he comes around and decides that he can't let inexperienced Jim Reed loose on another officer, so he decides not to leave the force.

Malloy and Reed learn of a serial home burglar stealing color TVs. They stumble upon the suspect's car with unusual results. Also, Reed must come to terms with his anger over a drug using mother that endangered her children to score dope.

Reed gets Malloy to agree to an early dinner when his wife puts him on a low-cal diet. However, one after another event prevents them from going code 7 all night long. Events include the theft of a man's sod, stolen credit cards, and a suspected car theft.

Reed and Malloy assist park rangers in catching a horse thief, a homesick Texan who was high on drugs at the time. The officers then chase two gunmen in a high speed pursuit.