The girls are finally graduating from high school and getting ready to leave home for college. But will they stay together or go their separate ways?

It's New Year's Eve, and a bold new Katie is finally ready to confess her feelings for Ryan. Cue the fireworks -- and a flaming espresso machine!

Alexa's working overtime to keep Christmas on track. But finding her old hospital bag stirs up memories that throw her off her holiday game.

An expensive mistake means Katie can't afford to go to London. But she's keeping it a secret so she doesn't ruin Alexa's epic birthday party.

Alexa agrees to speak at Lori's carnival-themed Stand Up to Cancer fundraiser, where Katie's coffee kiosk brews unexpected jealousy.

Alexa gets the doctor's OK to play basketball but struggles on the court. A heart-to-heart with another young cancer patient reminds her of how far she has come.

When Alexa and Dylan get into a fight right before the big Halloween party, Katie's sure she can fix it. But what if they're not meant to be together?

Alexa claims she's fine -- so the girls take her shopping for a Sweet 16 dress. Back at the house, a stressed-out Lucas goes to Dave for dating advice.

When Katie needs help prepping for a math midterm, Alexa offers to ask Dylan. Meanwhile, Jennifer still doesn't know her daughter has a job.

Senior prom is on Saturday, and Katie needs a date. (See also: the courage to tell Alexa something important.) Lori and Joe go overboard at game night.

Alexa's first high school dance is right around the corner. But a risky flu outbreak means she might not be able to go.

Katie applies for a job at the coffee shop without telling her mom. When Lucas and Gwenny go out on a date, the girls are determined to sabotage it.

Alexa's full of advice after getting her driver's license — but she doesn't know everything. Meanwhile at Wired, the new hire is Katie's worst nightmare.

With college applications looming, an aptitude test reveals Katie's true passion. But pursuing it is scary — and Alexa's "dream job" doesn't feel right.

Alexa's ready to leave cancer behind her, but it's not that simple. Meanwhile, Katie's trying to balance all the things -- and it's super complicated.

Alexa eases Katie's anxiety with an epic plan to crush senior year. Jennifer starts her new job, and Jack and Lucas help solve each other's problems.

A big fight on the first day of school leaves the girls feeling way out of sync. Lucas starts college, and Lori and Dave toast their 20th anniversary.

Being there for Spencer brings back memories Alexa would rather forget. Katie looks for leadership opportunities, and Jennifer preps for a date.

Alexa takes Katie miniature golfing to get her mind off the SATs. Lori plays matchmaker when Jennifer hires a handsome handyman.

After dating Joe for six months, Jennifer's ready for him to meet her family and friends. It's just dinner ... but Katie's got some concerns.

College acceptance letters are here. But did Alexa and Katie get into the same school? And why are things suddenly so weird between Alexa and Spencer?

Alexa's got such a great support system at the hospital that Katie isn't sure where she stands. Lori pours her anxieties into baking.

Katie is thrilled when chosen to study acting in London. But the $2,000 tuition is way out of her financial range. So she takes on a series of odd jobs trying to come up with the money to send her to the UK.

Alexa's excited to see Dylan again but senses Spencer needs her more. Katie organizes a food drive, and Dave goes overboard on holiday decorating.

Alexa struggles to keep her "real" life -- and her life with Spencer -- separate. A horrified Katie's convinced that her mom is dating Gwenny's dad.