A time traveling detective arrives from the future and enlists Astro and the infamous surgeon, Black Jack, to save the life of a prince from the past.

Toby has been enslaved by a robot circus owner and is forced into manual labour. There he befriends a young circus worker named Kathy. Dr Boynton's associate, Professor Elefun, comes to fetch Toby but the ringmaster refuses to let him go... Toby receives his new name, "Astro".

Balloons modelled in the shape of Astro are attacking people in the city and its up to Astro to clear his name.

Dr Boynton is so driven by his work as a robot engineer thst he neglects his promise to spend time with his son Toby at an amusement park. As Toby leaves the park, he is caught in a traffic collision. Before dying, Toby has his father promise him to make the new robot in his image and treat it like a son. Overcome with grief, Boynton completes the project and brings "Toby" to life. Unknown to Dr Boynton, a shady criminal called Skunk stole the plans for "Toby" and plans to make a robot of his own with a new circuit known as the Omega Factor.

Dr. Boynton and Toby depart on an ocean liner for America. Not knowing his own strength, Toby causes a huge mess during dinner. Angrily, Dr Boynton rejects Toby on the spot, declaring that he's just a robot and that he has no son. Meanwhile, Skunk attempts to teach Atlas his criminal ways and eventually takes Atlas on a mission to steel gold from the same boat that Dr Boynton and Toby are on...

Rescued from the circus by Dr. Elefun, Astro Boy starts school and struggles with the bullying from classmates for being a robot.

Astro's must stop Atlas' scheme to enslave humanity by series of technological thefts, one of which involves Astro's proposed robotic parents.

Astro and Dr. Elefun visit a fairytale theme park after an escaped swan/princess crash lands in their yard and tells them of the robots' plight.

Skunk convinces a powerful robot called Frankenstein to aid him in his crime spree. This crime wave leads to the deactivation of almost all robots in the city, including Astroboy.

A red cat becomes the only clue to the mystery of children who are disappearing.

While exploring a forest that has become a desert, Astro Boy discovers that Atlas is involved.

Astro aids a championship racer who hopes to win a global race.

Astro and his teacher, Daddy Walrus, are invited to the inauguration of the first robot president and are caught up in a plan to stop the ceremony.

After a spacecraft crashes to the earth Astro rescues a mining robot, Goliath, from the flames. Dr Elefun has Goliath's head removed as it contains a powerful neutron beam. But soon the head is stolen and Goliath starts to search for it...

Skunk causes trouble again, this time capturing a robot capable of invisibility hoping to use it in his schemes.

Astro meets his new sister, Uran.

Astro gets involved in a rivalry between robotic "families". However the two of the robots from the competing camps fall in love.

Astro captains the Second Expedition to Mars where strange creatures have been seen.

Astro attempts to stop Skunk's outer space pirating attempt when one of his classmates is kidnapped.

On a school field trip to see the Rainbow Comet up close, Astro and classmates are kidnapped by Atlas.

Astroboy visits a robot inhabited island where gangsters attempt loot uranium resources by enlisting the help of and a robot who can transform into any shape.

After luxury spaceliner Titan is struck by an asteroid, Astro and several others escape to the moon. They land in a crater with an atmosphere and Astro discovers the wreck of a Russian spacecraft from 1990.

A school field trip is interrupted by a robot constantly lying about a impending earthquake.

Astro Boy meets a mysterious woman and must stop a hostile alien invasion.

A power-hungry Sultan commissions a powerful fighting robot named Bruton (Pluto in the original), and sends him to battle seven of the world's strongest robots: Mont Blanc, Molnar, Brondo, Zeron, Hercules, Photar, and Astro.