Barnaby's investigation into the disappearance of a young girl hinges on a roommate who may have witnessed what happened to her. But the roommate herself now suffers from hysterical blindness because of the traumatic event. Barnaby must find a way to crack the case before the roommate becomes the next victim.

While investigating the death of an apparent suicide jumper Barnaby learns there was a jewel robbery in the building next door at the very same time the man jumped. Following his gut instinct he suspects the two incidents are connected.

At the request of his late son Hal's friend, Barnaby investigates a lodge owner who is suspected of murdering his wife. Even though he finds conclusive evidence to exonerate the man, Jones suspects that all is not as it appears.

While investigating the death of a man bitten by a rattlesnake, Barnaby soon suspects that there is more than one snake involved...and it's one that wears cowboy boots and has a prison record.

A race car driver gets caught cheating on his wife by his brother-in-law, and in order to keep his indiscretions secret he resorts to murder. Barnaby is hired to investigate by the father-in-law who thinks competitors killed his son.

A detective friend of Barnaby who is intent on catching a murderer, has been receiving letters from the man who is taunting him. But when he gave him too much information the man kills him and Barnaby sets out to find him.

After a woman's niece is shot and killed in a botched robbery attempt, she suspects that she was intentionally murdered and hires Barnaby Jones to investigate.

After an overseas shipping worker is killed on a dock under some suspicious circumstances Barnaby Jones investigates the death for an insurance company and discovers a trail of death on his way to uncovering the truth.

Barnaby investigates a jealous husband who he believes murdered a man for having an affair with his wife. But did he murder the wrong man?

A man dies under suspicious circumstances after being warned by a psychic and Barnaby Jones is hired to investigate. Barnaby doesn't buy the psychic mumbo-jumbo and suspects that once again money is at the root of all evil.

Barnaby Jones investigates the disappearance of a man he believes was involved in the theft of one million dollars in precious jewels. It isn't long before Barnaby suspects the man met with foul play and that the wife and defense lawyer of the man are involved.

The owner of a company calls Barnaby in to investigate after one of the members of the Board of Directors dies in a plane crash, shortly after leaving him a mysterious message hinting at possible troubles within his company.

Barnaby investigates the death of a motorcyclist found in the desert and discovers that it may be related to another case involving the disappearance of a beautiful young woman who was set to marry a wealthy, but disreputable business man.

Barnaby looks into the suicide of a woman who was married to a famous writer. Digging deeper into the case he discovers that the writers worst critic may actually be his biggest fan, and that his wife's suicide is looking more like murder.

It appears that every man who shows a beautiful young woman any type of affection or attention meets with an unfortunate accident, and Barnaby believes that it's more than just coincidence.

An insurance company hires Barnaby to investigate the theft of $500,000 worth of platinum from a jewelry company. During the robbery an employee is shot and killed by the robber, but Barnaby suspects it may be an inside job.

A beautiful young woman hires Barnaby to look into the death of her father who was apparently killed by a computer programmed machine in his own plant. It isn't too long before Barnaby suspects foul play rather computer malfunction.

The parents of an up-and-coming songwriter ask Barnaby for help in uncovering the truth after he dies of a heroin overdose.

Betty urges Barnaby to look into the death of an old girlfriend, and they soon discover that another old girlfriend of Betty's is directly involved in her death.

Barnaby is hired by a South American President to find his son who lives in LA. He finds him but learns he is also the Rebel leader, Javier he is presently at odds with.

A young widow hires Barnaby to investigate the "accidental" death of her husband of only four weeks. While investigating the case another young man who was once a suitor to the same woman winds up dead under mysterious circumstances, leaving Barnaby to believe neither death was accidental.

While investigating a deadly auto accident that killed two people including the chauffeur of a wealthy woman who herself was also seriously injured Barnaby suspects a sinister cover-up involving the woman's plastic surgeon and his nurse.

Barnaby is hired by a woman to locate her fiancé; who disappeared along with some her valuables. The man who is a conman, has moved on to his next mark but one of his former victims finds him and threatens to reveal all to his latest mark so he kills her. At the same time some of the woman's friends catches him in a lie.

The owner of a basketball team is informed that his star player once threw a game. The person who told him that, wants him to make sure that his team loses a game. So the owner kills him. Barnaby is hired by the man's wife who is the sister of the player to find him.

Cannon and Barnaby Jones investigate the death of a young woman who was about to expose the illegal activities of the large corporation she was working for. The crossover starts on Cannon S05E02 The Deadly Conspiracy (I).