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Comedy•Drama

The Best Episodes of Best Medicine Season 2

Every episode of Best Medicine Season 2 ranked from best to worst. Discover the Best Episodes of Best Medicine Season 2!

Binge this in 44m•Peaking at 8.3/10

Martin Best is a brilliant surgeon who abruptly leaves his illustrious career in Boston to become the general practitioner in a quaint East Coast fishing village where he spent summers as a child. Unfortunately, Martin's

Airs on

Seasons2

Episode Rankings

  1. #1 Fan Favorite
    Best Medicine Season 2 Episode 1 - Be Careful What You Fish For
    8.3/10(114 votes)

    #1 - Be Careful What You Fish For

    S2:E1

    While Martin continues to struggle with his blood phobia, a mermaid washes ashore in Port Wenn to the amazement of everyone in town. Meanwhile, Judith, a well-meaning townsperson (guest star Andrea Martin), creates havoc while on prescribed oxygen, Louisa continues to see Martin's girlfriend Eden for medical guidance and Greg and George's success from the seas urchin boom take its toll on the both of them.

    Director:Nancy Hower

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  2. Best Medicine Season 2 Episode 2 - Breakin' In Is Hard to Do
    0.0/10(0 votes)

    #2 - Breakin' In Is Hard to Do

    S2:E2

    When the Port Wenn pharmacy is robbed, including Louisa’s critical time-sensitive medicine, Martin deduces that the culprit desperately needs his help. Meanwhile, Greg and George clash with a rival food truck owner, Sarah tries to bond with Eden, and Martin is on the receiving end of a special brand of Port Wenn affection.

    Director:Unknown
    Writer:Unknown

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Season 2 Ratings Summary

"Be Careful What You Fish For" is the best rated episode of "Best Medicine" season 2. It scored 8.3/10 based on 114 votes. Directed by Nancy Hower and written by Liz Tuccillo, it aired on 9/20/2026. This episode is rated 8.3 points higher than the second-best, "Breakin' In Is Hard to Do".