Seven young adults with Down syndrome meet at a local recreation center and realize they have more in common than expected.

Concerns are raised about Elena's behavior after she has an altercation with Rachel; Angel wants to take his relationship with girlfriend Cristina to the next level; Sean's parents realize their son is ready to become more independent.

Rachel prepares for a date with a crush from drama class. Megan reveals a desire to have a baby, which concerns her mother. John records his first rap track.

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Megan catches up on businesses in Colorado while her Los Angeles friends prepare for a red-carpet ball; things become complicated between potential dating partners Steven, Elena, and John.

Sean heads to Las Vegas to attend a Justin Bieber concert; John receives a warning that he has one year to make headway in his music career or he will have to get a real job Megan tells her mother that she wants to return to California.

Meghan, Rachel, and Elena travel to Trinidad with their mothers for an international Down syndrome conference when real life intrudes in dramatic ways. Sean takes a road trop to Las Vegas to see singer Justin Bieber. Christina pursues a life-long dream.

A health scare force Megan to reassess her plan to move to California; Sean's blind date encourages him to get a tattoo; Christina develops a crush on her dance instructor.

The fathers plan for Stepven and Sean to become roommates; John performs a new song he hasn't quite mastered at a fundraiser; Megan travels to Los Angeles for a job interview.

Megan secures a job in LA and, when Brendan doesn't want to discuss marriage and babies, her decision to move to Los Angeles becomes easier. In a farewell lunch with her Dad she asks some hard questions. Cristina's jealousy and controlling behavior spins out of control, causing concern among her friends. Rachel, Bea and Mariano try to intervene.

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The friends spread their wings and fly towards independence. Cristina and Angel announce the date of their wedding and begin wedding planning. Rachel, determined to live on her own, asks Megan to be her roommate. John takes the necessary steps towards getting his driver's license. Sean's determination to get a tattoo drives a wedge between him and his father.

While picking out a wedding dress, powerful emotions are brought up for Cristina and Bea. Elena desires to take her relationship with William to the next level. On a journey to health and wellness, Megan and John visit the Chopra Center, where both amusement and self-discovery ensue.

Cristina and Angel meet with their wedding planner and learn the art of compromise. Rachel celebrates her birthday in Vegas surrounded by friends and family. Megan searches for an additional source of income to further her goal of financial independence and grow her “Megpire.”

Megan and Rachel make the big move into their new place, which presents its fair share of trials and tribulations. Hiromi and Stephen seek out guidance on whether or not they can move back to Japan and leave Elena in the US. Angel and Cristina hit a bump in the road over a misunderstanding about Cristina wanting to date other people. The group boogies down at Drag Queen Disco Bingo, where they meet Elena's new beau.

Megan and Rachel adjust to living independently, while Kris and Laurie struggle to let go; the Kellers start to teach Rocco independence; Sean finds comfort in his relationship with Caley.

With the help of some cute firemen and a self-defense class, Rachel and Megan learn to stay safe while living alone; they celebrate their independence with a no-drama party; John and Steven get behind the wheel at last.

As Cristina and Angel's wedding date quickly approaches, Cristina reaffirms her commitment to Angel by surprising him with a gift, while Angel takes lessons on being a good husband and prepares to move in with Cristina.