Bull and Benny represent a couple being sued by their baby's biological father for custody after a fertility clinic mistakenly used the wrong man's sample. As family court cases are solely decided by a judge, Bull and Benny worry about their best strategy at trial without a jury for TAC to analyze.

Bull returns to work following his heart attack with a new rich client for the firm to represent: an insurance company being sued by a dying mother for denying coverage of her liver transplant.

Bull finds himself serving jury duty while simultaneously mounting a defense for a woman on trial for killing her daughter's murderer.

Bull helps a doctor who crossed state lines to purchase a marijuana-derived oil to treat her patients in Virginia, where the oil is illegal. But the case is complicated when Assistant U.S. Attorney Sylvia Banner has the DEA arrest her for possession with intent to distribute.

Bull confronts his guilt over closing his psychiatric practice to start TAC when his former patient, a young woman who is a clinical sociopath, goes on trial for killing her brother. When Bull and Benny’s client has no memory of the crime due to her mental condition, they enter a "Not Guilty by Reason of Insanity" plea and aim to seat jurors that are sympathetic to mental illness.

Danny enlists her colleagues to help when her boyfriend, Gabriel, is arrested for being in the country illegally and threatened with deportation. Also, Bull represents a German national who is being sued by a museum over possession of a valuable painting.

Bull sees a visionary whereas the federal government sees a con woman, when he helps the defense of a charismatic entrepreneur, Whitney Holland, who’s accused of defrauding investors in her seemingly groundbreaking water filtration system company. As the trial gets underway, Bull focuses on selecting jurors whose belief systems allow them to see his client as a dreamer who never meant criminal intent.

Benny’s previous career with the District Attorney’s office comes into focus when Chunk, working with his law professor’s legal clinic, aims to get a new trial for Eddie Mitchell, a man he believes was wrongfully convicted of triple homicide by a prosecution team that included Benny.

Bull helps a famous social media influencer, Sadie Washington, take her father to court to overturn his legal guardianship over her empire, which he was granted after the young mogul suffered a public mental breakdown. To counteract any jury bias Sadie faces due to the public’s perception of her mental illness, they aim to select jurors who believe in giving people second chances.

Bull heads to federal court for a client accused of stealing his own scientific research from the company he works for, a corporation he says buried his ground-breaking work because selling medication is more profitable than curing diseases

Dr. Jason Bull, the brilliant, brash founder of a prolific trial consulting firm, combines psychology, human intuition and high tech data to create winning strategies that steer high-stakes trials in his clients’ favor.

Bull and his team tackle jury bias against their client, a woman on trial for the murder of a star athlete she very publicly accused of assaulting her. Also, the case brings Benny face-to-face with his former flame, Amanda, a fellow attorney he hasn’t seen since their breakup.

Dr. Bull and his Trial Analysis Corporation (TAC) team must formulate a new defense strategy when they discover the jury has a subconscious gender bias toward their client, a female pilot accused of negligence after one of her flights crashes.

Bull’s team is rocked when their client, Elliott Miles, is found guilty of murder, and they must regroup as the trial enters the penalty phase in order to prevent him from being sentenced to death. But when new evidence emerges that could prove Elliott’s innocence, Bull must find a way to present it in court without being found in contempt. Also, Marissa faces hard truths about her relationship with Bull.

When the team consults for the NYPD on the defense of a police officer accused of excessive force in the shooting of an unarmed man, the social politics surrounding the case create tension within their own ranks.

Bull helps a teachers union represent a woman who is being prosecuted for helping an impoverished student pass an important test, but who may be the scapegoat for a larger cheating scandal.

A friend from Bull’s past enlists his services to help convince a jury that a domestic abuse survivor who shot her husband in his sleep is not guilty of murder because she feared for her life and the life of her unborn child.

Bull and the TAC team help one of their own when Marissa’s restaurateur husband, Greg, is charged with involuntary manslaughter after one of his employees dies in a kitchen fire allegedly caused by negligence. During voire dire, Bull and Benny aim to select jurors who will believe the fire was an accident and not a pattern of irresponsible management.

Bull takes on a pro bono client who was poorly advised by his public defender to plead guilty to a misdemeanor assault charge and is now facing felony manslaughter after the victim dies.

As Bull prepares for fatherhood, his work at TAC suffers without his top attorney, Benny, who quit in reaction to Bull’s romantic reconnection to his ex-wife and Benny’s sister, Isabella. In addition, the team faces a difficult time in court as they mount a defense for a young bartender on trial for involuntary manslaughter.

Taylor becomes personally invested in having Bull help a dancer, Jessica, bring a civil suit against a real estate mogul who assaulted her at a gentlemen’s club when the district attorney’s office refuses to pursue criminal charges. As the TAC team faces an uphill battle in court due to the defendant’s fame and popularity, Bull aims to select jurors who believe privileged people don’t deserve special treatment.

When Bull and Trial Analysis Corporation (TAC) help a young woman fight a drug patent lawsuit, they’re forced to travel to Callisto, the small Texan town where Bull suffered the only trial loss of his career.

When Bull assists CEO Ginny Bretton, whose company is accused of killing an employee with its self-driving car, he discovers his client is keeping a major secret that could sabotage a trial win.

When Bull assists Jules Caffrey, a high-powered attorney on trial for his fiancée's murder, he takes advantage of his client's penchant for courtroom theatrics by letting him defend himself.

Bull makes a deal with top criminal attorney J.P. Nunnelly to defend Benny when he goes to trial for misconduct in a case related to his former career with the District Attorney's office.