Chelsea's niece steps in as co-host, and Bryce Dallas Howard offers tips on growing up in a famous family. James Carville marvels at Trump's behavior.

Sparks fly as Chelsea talks cats, fame and Obama with comedian Marc Maron and actress Natasha Lyonne. Plus, Olympic swimming champ Nathan Adrian.

Hasan Minhaj of "The Daily Show" recounts his hair-raising trip to the RNC, and the women of "Mr. Robot" celebrate their stereotype-defying roles.

Comedian David Cross mourns the "quaint" early stages of Trump's campaign. Chelsea and "Sully" actor Aaron Eckhart talk phobias and hypnosis.

Neil deGrasse Tyson explains the hazards of zero-gravity intimacy. Michael Sheen talks "Masters of Sex." Jenny Mollen obsesses over Jason Biggs's ex.

Sarah Silverman opens up about a recent health scare and her fiery DNC remarks. Gloria Steinem talks politics and her Emmy-nominated Vice show.

Shannen Doherty offers a raw glimpse of how cancer has redefined her self-image, upended long relationships and changed her life -- for the better.

Chelsea Clinton speaks out about her mother's resilience, the high stakes in this election, and an "offensive" ploy by Trump. With Rose McGowan.

Chelsea sifts through the dizzying emotional and political fallout of the election with help from Sen. Barbara Boxer, Mary McCormack and Nikki Glaser.

Mayor Aja Brown fights to rebuild a city plagued by turmoil. David Axelrod offers insights on Obama. Michael Kelly talks eerie 'House of Cards' plots.

In the land of vodka, Chelsea braves a bracing spa ritual, tries rhythmic gymnastics with Maria Sharapova and probes the mystery of Russian men.

Chelsea invites a politically diverse group including W. Kamau Bell and S.E. Cupp to dissect the rise of Trump and the issues that divide Americans.

Chelsea quizzes “Guardians of the Galaxy” star Chris Pratt. Amy Schumer, Goldie Hawn and Wanda Sykes play a guessing game. Plus, Rep. Adam Schiff.

The rapper joins California Lt. Governor Gavin Newsom to push for game-changing action on pot. Chelsea tries working out stoned with an MMA fighter.

Avowed non-parent Chelsea grills Kate Hudson and others about the appeal of raising kids and has her nails done by a gender-nonconforming 9-year-old.

The actress responds to 'Ghostbusters' skeptics and flouts fashion norms with her new clothing line. Zachary Quinto celebrates a 'Star Trek' first.

Chelsea asks Tinder CEO Sean Rad for help with her profile and heads into the wilderness for survival school. With Eric André and Joel Kinnaman.

Model Ashley Graham and country singer Jana Kramer bond over their brushes with public shaming. Plus, beauty pageant boot camp and comic Jimmy Carr.

The kids from "Stranger Things" talk sudden fame and welcome a surprise visitor. Abigail Breslin slams an offensive tweet. Plus, comedian Bob Saget.

Oscar winner Patricia Arquette makes an urgent plea for equal pay, and Aisha Tyler rejects the toxic female relationships depicted on TV.

"OITNB" actress Diane Guerrero reflects on her parents' deportation. Mike Colter shares the symbolism behind Luke Cage's hoodie. With Craig Ferguson.

"Bridget Jones" star Renée Zellweger looks back on a life-changing phone call. Chris Geere recalls an awkward sex scene. Plus: Who is Alex Trebek?

Amy Schumer riffs on awkward family dynamics, dating life and pressure from fans. "Shark Tank" star Mark Cuban explains his change of heart on Trump.

Chelsea taps the conservative pundit's "body double" for a biting interview. Kristen Bell finds a cure for online gloom and doom. With Jacob Soboroff.

Jason Biggs and Jenny Mollen go to work for Team Clinton. Journalist Jorge Ramos warns of a rising tide of hatred. With Isla Fisher and Thomas Lennon.