Amber Tamblyn helps celebrate Thanksgiving; Reggie invites some of his favorite comics over for dinner; an orphan returns.

David Krumholtz reviews Scott's hosting abilities; Arthur Steinborn teaches everyone his memory technique; Scott and Cudi are visited by an avant-garde painter who wants to give the show a more artistic spin.

Nathan Fielder makes and appearance; Scott and "Weird Al" try their best to freak out Nathan Fielder.

The crew is visited by some American heroes to try to bring the country back to its moral foundations; Kaley Cuoco finalizes her will; lifestyle coach Karen helps Scott style his inside.

Scott's estranged family visits; Ben Folds discusses his new start-up business; Weird Al shows his new sports documentary; world-traveler Martin Moreland visits.

Comic Amy Poehler discusses her hair and her feud with Mad Magazine.

Guest star Clark Gregg does a show-and-tell with props from his movies and Scott issues a warning to some badly behaved celebrities. We also find out about a controversial new holiday for naughty little boys.

Michael Sheen teaches Scott about the birds and the bees, and entertainer Victor Diamond explains his various medical conditions. Meanwhile, Scott receives accolades for saving Wonky Cat, the world's weirdest cat.

Comic Zach Galifianakis discusses his place in the pantheon of comic actors and talking dogs.

Pee-wee Herman casts spells and saves Scott's life for Halloween; Reggie has a surprise costume of his own; Scott finds a killer from his past; Reggie Watts; Pee-wee Herman.

A flash forward to the final episode; Zach Galifianakis makes his first appearance since his big accident; characters from past seasons come back to say goodbye; ongoing storylines get resolved; a surprise wedding.

Jesse Tyler Ferguson explains the great chemistry behind "Modern Family," and cyborg rights activist Nelz Hebber has some ideas for the future. Meanwhile, Scott tries to balance his family life with his career as a talk show host.

Joe Jonas demonstrates his unusual cellphone replacement; Scott arranges a memorial service for an old friend; Maxwell Keeper discusses his workplace; and a sneak peek at Scott's movie.

Guest Rashida Jones learns how to stay relaxed while monster truck driver Darryl Drummond announces his retirement. Plus, Scott helps a scorned spouse get closure.

Craig Robinson has a question on his mind; Reggie is taken up to space to battle an alien race; Scott helps renovate homes; a comedy team hides a deadly secret.

Joel McHale talks about his unusual birth; a Hollywood actor discusses his recent firing; Scott's new machine is running the show; Scott receives a warning from the future.

In the Season 5 premiere, Weird Al Yankovic signs on as band leader and guest Kevin Bacon leads a tour of Kevin Town. Also, a leprechaun hassles Scott.

Host Scott Aukerman interviews Seth Rogen about his recent vacation. Scott uses his psychic powers to listen in on people's most private thoughts. The world's top child bird caller visits and performs. Bandleader Reggie Watts interrupts the show to paint a portrait of Scott. Scott leads everyone in the game "What's Their Ailment?"

Scott invites Andy Richter to the couch along with actor Mike Hanford. Later, Scott and Reggie visit the big apple to invest their money. Finally, we find out who stole Reggie’s bike. Special Guest: Michael Ian Black.

Patton Oswalt and Scott compete for the same acting role, while a turtle expert is going through an emotional breakdown. We find out Reggie’s real name and witness what unsuspecting bystanders do with an unprotected laptop.

Rapper Schoolboy Q lets us know what it’s like to be "Man of the Year," and Aaron Neville (Horatio Sanz) explains his anti-violence campaign. Reggie is caught in a war between two musical groups vying for his attention.

In this Valentine’s Day Special, Scott must help Reggie land the girl of his dreams. Scott has a shoot-out with guest Mark Duplass, and etiquette expert Miss Polite dispenses advice

Dax Shepard demonstrates the difference between comedic and dramatic acting, and professional gift guesser Bertram Jollymore shows off his talents on the couch. Meanwhile, to deal with rising rent costs, Scott and Reggie find a new roommate.

Scott's secret identity is at risk when his friends win the Comedy Bang! Bang! "Interview a Fan" contest. Meanwhile, Thomas Middleditch proves he's an expert at accent work, and shaman Harmony Moonglass leads the group in a guided mediation.

When a wizard appears on-set, Scott agrees to help save his realm if they can perform in a magic show together. James Marsden acts with a real rabbit and discusses his good looks, and Mr. Celebrity shares Hollywood gossip. Scott and Cudi preview their new zombie movie.