Drew Peterson speaks to Natalie Morales in his first on-camera interview in over a decade about the murder of his ex-wife, Kathleen Savio, and the disappearance of his fourth wife, Stacy.

Josh Mankiewicz reports the latest developments following an arrest in the Kristin Smart case; Craig Melvin reports on the mysteries surrounding the powerful Murdaugh family of South Carolina.

Insiders close to the case of missing Colorado mother Suzanne Morphew speak out for the first time.

California detectives reveal new details about the alleged kidnapping of Sherri Papini.

New Jersey detectives investigate a report that a 5-year-old boy vanished from a carnival.

Family members and investigators speak out for the first time on network television since the death of “Love Has Won” spiritual leader Amy Carlson, known to her followers as “Mother God.” The case gained worldwide attention after deputies found her mummified body covered with Christmas lights in a Colorado house where members of the group stayed.

A Connecticut mother speaks out about her fight to keep her assailant from walking free.

Detectives search for a motive in the fatal stabbing of former Sen. Linda Collins of Arkansas.

New interviews reveal the latest twists and turns in the case of Pam Hupp, charged in the murder of her close friend Betsy Faria; Betsy's daughter, as well as the prosecutor behind the wrongful conviction of Betsy's husband speak out.

Investigators desperately search for a killer after Florida teacher Denise Hallowell is found murdered. Dennis Murphy reports.

Insiders reveal new details on the 2016 murder of a plastic surgeon in Asheville, N.C.

Investigators search for answers after a 17-year-old is murdered after a Valentine's Day dance.

A Phoenix family gathering ends with a suspicious death and more than a decade of questions.

A triple murder divides a small town in Kentucky. As secrets come tumbling out, residents begin to wonder: How well do we really know our neighbors? Keith Morrison reports.

A man goes overboard on a romantic sunrise cruise with his wife on Lake Coeur d'Alene in Idaho. Investigators begin to think his death may not have been an accident. Keith Morrison reports.

New evidence, exclusive interviews, and an in-depth look at Lori Vallow and Chad Daybell, the Idaho couple charged in the murders of Lori’s children JJ & Tylee. Keith Morrison reports.

After an Oregon chef is murdered, investigators uncover a potential clue written years earlier.

A mystery in paradise unfolds when a woman vanishes from a luxury yacht in the U.S. Virgin Islands.

Insiders speak out about the latest developments in the suspicious death of a New York woman.

New details expose how the Gucci empire was undone by jealousy, backstabbing and an act of murder.

Detectives search for a motive in the fatal stabbing of Oregon mother Annastasia "Annie" Hester.

When 18-year-old Anjelica Hadsell disappears, the investigation uncovers a sinister betrayal.

Investigators uncover a puzzling connection between two women who disappeared two decades apart.

New details emerge in an alleged murder-for-hire plot targeting a former NYC cop's husband.

A family’s search for answers in the 2014 disappearance of 28-year-old Fayetteville, North Carolina construction worker James Chambers. Andrea Canning reports.