The villagers throw the Ellinghams a farewell party and Ruth helps Mrs Tishell deal with the news and encourages her to attend, but it seems that Martin and Louisa aren't going to make it because a farmer has spotted their lost dog.

Upon discovering Doc's fear of blood, the village starts buzzing with the news. Bert insists on playing a practical joke, but Doc isn't laughing.

Dr Martin Ellingham and Pauline are surprised by the number of patients coming to see him on the last day before his Surgery closes and he moves to London.

Louisa is leaving for Spain, Bert and Jennifer's engagement party goes off with a bang, and Al is hailed as a hero for saving Caroline's life.

A Salvation Army member arrives in Portwenn to try to trace a missing woman, Danny asks reluctant girlfriend Louisa to move into him, and PC Mark Mylow's medical check has a shock result.

Martin prepares to face his hearing, but despite having closed the practice, he finds all his patients are trying to make appointments. An American tourist who visited Portwenn previously returns to the town, hoping to research her family tree. However, she also has a medical issue, and comes to the troubled doctor seeking his advice. Louisa goes to see Chris to find out how serious the situation is, while the townsfolk take steps to show Martin how much he is appreciated.

The curmudgeonly GP struggles to come to terms with his new role as a father, having planned to resume his career as a consultant in London before the arrival of his and Louisa's as-yet unnamed son. To make matters worse, he begins to have serious doubts about the competency of his replacement Dr Di Dibbs when she misdiagnoses a patient as well as herself. Martin is then dealt a devastating personal blow after hearing his aunt Joan has died. (This Episode Is Rated TV-PG-V)

Mrs Tishell decides she can no longer hide her love for Martin and, fuelled by a cocktail of drugs, takes drastic action. While James Henry is in her care, she boards a bus out of Portwenn and leaves a message for Dr Ellingham to `meet them at the castle', forcing Martin, Louisa, Ruth and PC Penhale to mount a desperate search for the pair.

Penhale decides to have a Police Open day to raise community awareness, but the only genuine visitor is an angry farmer who has had three of her sheep stolen. Meanwhile, Morwenna decides to take Al away for the weekend to try out Hannah’s new glamping site, but the trip does not go well as Al accidently burns down the yurt. Elsewhere, James has started biting not only Louisa but other children at the nursery. Louisa speaks to Tina about it, but is surprised to find out Tina has spoken to their lecturer about it too.

Martin rushes to Ruth's for a medical emergency, and preparations for Morwenna and Al's wedding do not go to plan. Elsewhere, Martin takes his final GMC assessment under the watchful eye of eminent surgeon Bernard Newton, who monitors Martin's skills in assisted surgery.

Martin's estranged parents charming Christopher and Margaret make a surprise visit, school secretary Maureen Tracey visits the doctor with what she thinks it is a thyroid problem, PC Mark Mylow announces he's getting engaged, and when Danny Steel collapses, Dr Ellingham has to carry out emergency surgery to save his life.

Martin and Louisa are about to get married but will it ever happen. Martin is feeling irritated by PC Penhale, who wrongly believes that he is going to be the best man and Louisa is also late for the service. The vicar has serious doubts as to whether she will turn up, leaving Martin on edge. After she finally arrives the couple are married. Things after the wedding don't go as Martin hoped and Ruth has a difficult time looking after James.

Martin and Louisa go on a date, but his usual bluntness ruins a romantic moment, and Louisa ends the struggling relationship. However, a friend of Louisa's visiting from the City, Holly, injures her back on the beach, and is forced to remain in Portween. Martin has to treat her at Louisa's house, while at the same time trying to overcome his own distraction at Louisa's dismissal of him.

Martin's medical career remains under scrutiny, as a GMC representative has come to assess him and his surgery.

Ruth is concerned about becoming increasingly forgetful, and is even more perturbed when Martin offers to perform a mini mental state examination.

Martin has to rush Buddy the dog to the vets. Meanwhile, Mrs Tishell's young cousin Sarah joins her for some work experience, but it does not go to plan, and one of Louisa's clients arrives at the surgery unannounced, posing a dilemma.

When Martin is talked into taking baby James to playgroup, he is forced to sing along with the other mums. As the parents pair up, one of them says she is worried about her daughter, to which Martin replies that the girl is probably just backward. Al helps Ruth move into a cottage in the village where she meets her new neighbour, a grumpy old man called Moysey. When Moysey goes for a repeat prescription for his asthma, Martin notices that his breathing has got worse - but he takes exception to being poked and prodded. Al admits he would like a girlfriend and asks Morwenna if she has any single friends. Morwenna asks her mate Janice, who is not impressed by the idea. So a desperate Al decides to sign up with Cornish Couples, a dating website.

Louisa and Martin decide to make a go of it, starting with a conciliatory dinner but Louisa is concerned when Martin fails to show up. In fact he has been taken prisoner by elderly Annie Winton, who wants him to save her terminally ill husband Jim, despite Jim's more stoical attitude. Louisa and Joe Penhale track him down and the outcome provides a solution to the Ellinghams' marriage problems. There is good news too for Al, as not only have Ruth and Bert decided to go into business to market Bert's whiskey to promote Al's B & B but he also gets a date with ...

Martin is left holding the baby when Louisa has to take Year Six pupils sailing. He has to collect James from nursery every afternoon, but with surgery hours Martin is constantly late.

Morwenna’s parents Jack and Tara pay a surprise visit, having been working as missionaries in Kenya. However, the reunion is tinged with sadness when it turns out that Morwenna’s mother has liver cancer, and has decided against treatment because of her faith. Louisa’s first online call for her new course does not go as planned – especially when Martin tells the lecturer exactly what he thinks – and Joe investigates a break-in at the school where nothing has been stolen. Martin Clunes stars in the comedy drama, with Jessica Ransom, Caroline Catz, John Marquez, Kevin Doyle and Rebecca Lacey.

Louisa has problems at school with Toby, Angela Sim’s Nephew. Meanwhile, Al has a ‘Large Whiskey’ order and has to ask Bert for some help, and Mrs Tishell seems to be having a delayed onset of mourning. Elsewhere, Martin and Louisa decide to try Mel’s suggestions of using amber beads to help James while he is teething.

Martin wakes up to an empty bed. When he goes looking for Louisa he discovers she is trying to write her resignation letter.

After having his career scrutinised by the General Medical Council because of his blood phobia, Martin makes efforts to overcome his fear and begins to question whether he made the right decision about resigning.

The news of Martin's Imperial College job offer is flying through the village, but the Ellinghams are yet to make a decision. Caitlin blames Bert for the flooded pub cellar, and an emergency on the rocks helps Morwenna make some important decisions.

When one of his Aunt Joan's former beaus comes back to Portwenn to woo her, Doc must butt in after discovering the man has a serious heart condition.