Martin and Louisa search for a nursery now that Janice has left, and Mrs Tishell is shocked to find out that Al has very high blood pressure. Louisa also helps with the diagnosis of a pupil, which spurs her on to explore the possibilities of a change of career. This is not welcome news for Martin, who dislikes any kind of change, even if it could be for the better. Elsewhere, Ruth is approached about selling her farm.

PC Mark Mylow can't persuade Dr Ellingham to be his best man, but Al Large agrees. The stag weekend – a camping trip – goes wrong when an adder bites Mark’s ankle and he suffers a potentially fatal allergic reaction. Meanwhile, Dr Ellingham deals with a spate of weever fish stings among teenage boys playing a dangerous game of dare.

Mrs Wilson, the hypochondriac owner of the Wilson hotel, forces her attentions on a very indifferent Martin, which makes Louisa jealous anyway. Joan dates a much younger man than her, much to Martin's surprise.

Martin is called to an emergency at a local farm, but much to his annoyance the sick farmer, Ron Pickford seems well enough to be managing his lambing sheep.

Maggie gets the all-clear from the doctor and decides she will return to Bude, forcing PC Penhale to take desperate measures to persuade her to stay in Portwenn. Ruth uncovers a raft of family heirlooms while clearing out a barn at the farm, and the mounting tension between Martin and Louisa peaks when she discovers he has booked a date for James Henry's christening without consulting her.

When a nasty stomach virus hits Portwenn, half the village takes ill, and Doc thinks he has traced the virus's source to the local swimming pool.

After turning down lovely teacher Louisa's invitation to a village dance, the socially awkward Doc treats a park ranger with an unusual problem.

Pauline looks set to achieve her ambition of joining the Portwenn Lifeboat crew. However, her joy is short lived when she is confronted with the chauvinistic behaviour of her shipmates. Martin is accused of murder by the husband of a woman who died in his care.

Martin suspects Louisa may have anaemia. Aunt Joan is forced to receive treatment from Martin after nearly running someone over. The Doc is approached by Alison Lane, who worries about her daughter Delph's behaviour.

Louisa's hippie mother Eleanor arrives in the village, immediately taking over Martin's kitchen to prepare a herbal tonic, which she later gives to the baby to stop his crying. A culinary rivalry develops between Bert and Mark Bridge, the landlord of the Crab and Lobster pub, at Portwenn Fun Day with both keen to take advantage of the event by providing food for the spectators.

The irascible medic decides to move out of the Surgery to give Louisa space, leaving Mrs Tishell concerned he will not be able to look after himself on his own. Elsewhere, PC Penhale helps Janice babysit, and Al is very concerned when he finds out about Bert's behaviour and hears there are bailiffs at the restaurant.

Louisa is shocked and Martin suspicious by the unannounced return of her father. Ruth is helping Martin with his blood phobia when she discovers his predicament, and an unexpected caravan squatter thwarts Bert's dreams of making a quick buck.

After developing a sudden fear of blood, successful surgeon Dr. Martin Ellingham abandons London for a general practice in a quiet Cornish hamlet.

Quirky Doc Martin opens his village practice, only to discover that most of his 'patients' enjoy using his waiting room as a makeshift social club.

An outbreak of what the Doc suspects is Impetigo leads to problems for Louisa, who must decide whether to follow the Doc's orders to force the infected children to stay at home, or to help the parents by allowing the children to attend school. The decision is made harder by her impending interview to take over the job of Head Teacher - in front of a board of governors that (to his surprise) includes Doc Martin. Meanwhile, an accident in the Fish and Chip shop leaves Bert behind the fryers and the owner's son, Peter, in need of somewhere to stay while his mother is in hospital. His first choice is with none other than a certain Doctor Martin Ellingham...

The Doc deals with a strange family who seem reluctant to let him make house calls, and whose passion for taxidermy seems to hint at a dark secret involving their missing mother. PC Mystow also has family problems when his overbearing sister moves in a sets up shop - much to the Doc's disgust - as a herbalist. A chance remark by Pauline sets Al on a path that could well destroy his relationship with Bert.

Anthony and Terri Oakwood move in next door to Louisa with their son, Sam, who is given extreme freedom by his parents to express himself. The new arrivals interrupt a planned dinner between Louisa and Martin, and Martin leaves abruptly.

It's Martin's wedding day and he manages to offend the vicar who is due to conduct the ceremony by suggesting he has a drink problem. When they struggle over a bottle of whisky, the vicar falls over, fracturing his pelvis and Martin has to find a replacement. Pauline suggests the former vicar of Delabole, who strikes a deal. He will conduct the wedding ceremony if Martin will examine his sick pig. Bert and Al are putting the finishing touches to the wedding banquet when disaster strikes. Last in the series.

Dr Martin Ellingham is shocked to find Louisa and Aunt Joan knocking at his door before the Surgery has opened. Louisa has had a medical scare and wants Martin’s reassurance that everything is fine.

Dr Martin Ellingham is called to Louisa’s new home after she has a dizzy spell while shifting furniture. Martin urges her to slow down, but is shocked to learn that Louisa has applied to be her school’s headteacher again.

PC Penhale is shocked by the unexpected arrival of his ex-wife Maggie, who appears to have forgotten that they separated years ago and wants to know why he left her. Eleanor goes on a date with local fisherman Paul Hale, an old friend she has not seen since school, while Martin and Louisa finally agree on a name for their baby

Bert Large's restaurant business is financial trouble. He can't even afford the food and drink for a charity event to raise money for Florence Dingle's cat sanctuary. Mrs Dingle is distraught. She desperately needs the money to continue to look after the cats and kittens in her care. Bert is also being chased by loan sharks Alastair Tonken and his son Norman for the repayment of £1,000 they gave him to clear his debts, warning of repercussions if he doesn't pay up.

When one of his Aunt Joan's former beaus comes back to Portwenn to woo her, Doc must butt in after discovering the man has a serious heart condition.

Dr Ellingham visits an elderly patient in the villiage, but has to contend with her irate son, who turns out to be one of Louisa's ex-boyfriends. Things become even more complicated when he meets the new receptionist and sees a patient who claims he was injured while being mugged but refuses to give a statement to the police.

The people of Portwenn are concerned for Radio Portwenn's DJ Caroline Bosman, whose increasingly erratic behaviour has them suspecting that she has been hitting the bottle. The Doc has to deal with an elderly patient whose personal aroma can clear a room, but is unable to determine a medical cause for the stench. PC Mylow hopes that his pheremone spray will endear him to a pretty newcomer to the village, while the Doc/Louisa/Danny triangle gets even more complicated.