Doc’s grandmother transports Doc to the magical world of McStuffinsville where she will carry on a family tradition by expanding her practice to the McStuffins Toy Hospital. There, on her first day as chief resident, Doc must tend to Stanley, a lonely, brokenhearted toy.

Doc enlists Lambie, Stuffy, and Chilly as Toy Med Students to help her take care of all of the patients at McStuffins Toy Hospital.

Doc appoints Stuffy head of the Vet Clinic at McStuffins Toy Hospital.

On their first night shift, Lambie is in charge of the Hospital Nursery but cannot get the babies to sleep.

Chilly schedules too many appointments for himself.

Doc and the toys receive 4 identical toy babies as Lambie has a problem telling the babies apart.

As Stuffy hurts himself playing a jousting match, he fears his first ambulance ride to the hospital.

A new nurse upstages Hallie and she no longer feels needed.

Doc responds to an emergency call during an accident at Southwest Sal's Ranch. It teaches you the importance of staying calm and following directions.

When baby toy Cece gets dirty, Doc and her toys have to get her clean, and they have to do it fast. Doc's baby sister Maya has just woken up from her nap and wants Cece, but she's too dirty to play with, and that makes Maya cry. Doc tries to give Cece a bath, but every time she tries to get her in the water, Cece cries.

After getting a crown-cussion, the Wicked King turns into a difficult patient.

Doc and her toys travel to the Giant Snow Globe outside McStuffinsville to help one of the Snow Peeps.

Hallie is so excited after being chosen to sing the opening song for the Foosball Game, she over-practices and loses her voice.

The Toy Med students must learn how to diagnose a patient without Doc's help.

The toys learn about bedside manner as they take care of Karaoke Katie, a doll who is disappointed about having to cancel her show because her batteries won't hold a charge.

After her bank gets a crack in it, Nikki Nickel needs to stay at the hospital overnight.

While exploring the Royal Lands, Sir Kirby loses his buddy and gets hurt.

When some of the toys get hurt at Bobby’s birthday party, Doc teaches them about bounce house safety.

While Hazel is in the hospital, Stuffy tries to sneak Squibbles in to cheer her up.

When Mayor Billington’s beak gets jammed during a speech, Doc teaches him that speech impediments are nothing to be embarrassed about.

After hearing there’s a monster in Bathtub Lake, Doc and the toys go to investigate.

When Chuck, the wind-up chicken, crosses the street without looking, he unintentionally causes accidents.

When Doc and the toys discover a broken birthday present, they rush to fix it before its child returns.

When Camille, a toy camel, gets hurt, it’s up to Doc and the other Med Students to convince her to go to the hospital.

When Doc is unable to see inside a toy’s fluffy cheek, she decides to do a CAT scan to figure out the problem.