When Cece accidentally gets hold of Lambie's Toysponder and transports herself to McStuffinsville, Doc and the gang must embark on a rollicking adventure to find her.

Spritzy Mitzi, an octopus shaped sprinkler toy, ruptures a sprinkler tentacle after getting a pebble stuck in one of her sprinkling holes after ignoring Stuffy's advice on having Doc checking it out first.

Niles, Donny's toy crane, refuses to have his old bandages removed when they start unraveling. Song: In A Flash Sickness: Y.O.B. Itis (Yucky Old Bandage Itis)

Awesome Guy injures his arm while showing off his awesome strength and Doc orders him to rest up.

Chilly turns pink from Doc's red scarf after being accidentally washed in the washing machine by Doc's dad.

Doc discovers a fashion doll named Dress-Up Daisy stuck in a tree and tries to calm her down from panicking while rescuing her.

Sir Kirby and The Wicked King get stuck together with paste after battling with Donny's cardboard monster, so they try to get unstuck.

The toys learn about bedside manner as they take care of Karaoke Katie, a doll who is disappointed about having to cancel her show because her batteries won't hold a charge.

Doc helps Hallie hear better after she has trouble hearing. Song: Have You Heard?

Doc tries to fix Millie the Microphone when she can't stop repeating words. Song: If You Got The Hiccups Sickness: Repeatitis

After discovering that she couldn't fix Maddie's toy mouse, Norton, in the park, Doc's dad builds a mobile clinic for her to fix toys when she's away from her clinic.

The other players in the Foosball court are ready to play but Johnny Foosball isn't ready because he is suffering from a sticking problem and is reluctant to tell his teammates about it.

Doc helps Hermie, her toy crab, after his arm was torn out by Emmie and Alma's new puppy Rudi. Song: You Can Do It! Sickness: Torn arm

Donny's toy truck, Tremaine, learns how to keep still to get repainted. Song: Keep Still

During an adventure game, Stuffy's tail gets ripped, but he won't ask for help and soon it gets worse as he loses more stuffing from his tail.

Doc fixes Gustave, the green gator on Donny's Gulpy Gulpy Gators game after he eats too many marbles. Song: Be Good To Your Tummy

Doc discovers that Donny's toy knight, Sir Kirby, is dirty. Song: Ba-Ba Bubbles!

Alma's xylophone toy, Xyla, loses a key by accident while being repaired for a loose screw. Song: Rocking The Right Note

When Doc accidentally gets sand in her eye, she finds out what's wrong with Will's toy digger, Riggo, when his scoop gets stuck. Song: Dig, Dig, Dig Sickness: Stuck Scooper

Boomer, Emmie's deflated Soccer ball refuses to be reinflated due to having a fear of needles. Song: Here For You

When Santa Claus goes missing, it's up to Doc and the Pet Rescue Team to deliver all of the presents for all of the kids in the world before Christmas Day.

Doc helps Henry's Telescope Aurora when she suffers from blurry vision. Song: Stars, Stars (Planets, Stars And Galaxies)

During a sleepover party, Doc discovers that Sir Kirby is afraid of the dark and cures him of his fear. Song: We Can Light The Night

While practicing their Juggling Jacks Act for Buddy's birthday party, Big Jack hurts his crank after Donny crashes into him while practicing some defensive soccer save moves, leaving him unable to perform.

Doc’s grandmother transports Doc to the magical world of McStuffinsville where she will carry on a family tradition by expanding her practice to the McStuffins Toy Hospital. There, on her first day as chief resident, Doc must tend to Stanley, a lonely, brokenhearted toy.