Derrick Campana specializes in designing prosthetics and orthotic braces for animals. Derrick will fit Jabu, an elephant in Botswana with a life-threatening injury, with the world's first elephant orthotic leg brace, hoping to save his life.

Ali Bee, her husband Tim, and daughter Izzy spend their time rescuing and rehabilitating koalas in their home in Australia. Crikey the koala was a baby that was found alone and very sick. Now, it's time for the family to release him into the wild.

British Marine Pen Farthing is the founder of Nowzad, Afghanistan's only official animal sanctuary. When a U.S. soldier rescues six puppies while deployed and can't bring them home, Pen and his team are on a mission to get them reunited in Texas.

Animal Defenders International (ADI), led by Jan Creamer and Tim Phillips, has already helped ban the animal circus industry in over 40 countries. When their organization arrives in Peru, they embark on their biggest animal rescue challenge yet.

Katherine Connor and her children run an elephant sanctuary that rescues, rehabilitates, and re-wilds elephants from Thailand's tourism and logging industries. Now she wants to rescue an older elephant, Pang Fai, and release her from chains forever.

Chimp expert Estelle Raballand has formed an incredible bond with Ponso, a chimp who lives alone on an island and has been dubbed the loneliest chimp in the world. She's determined to find him a companion and thinks she has found the perfect match.