Derrick Campana specializes in designing prosthetics and orthotic braces for animals. Derrick will fit Jabu, an elephant in Botswana with a life-threatening injury, with the world's first elephant orthotic leg brace, hoping to save his life.

Ali Bee, her husband Tim, and daughter Izzy spend their time rescuing and rehabilitating koalas in their home in Australia. Crikey the koala was a baby that was found alone and very sick. Now, it's time for the family to release him into the wild.

British Marine Pen Farthing is the founder of Nowzad, Afghanistan's only official animal sanctuary. When a U.S. soldier rescues six puppies while deployed and can't bring them home, Pen and his team are on a mission to get them reunited in Texas.

Animal Defenders International (ADI), led by Jan Creamer and Tim Phillips, has already helped ban the animal circus industry in over 40 countries. When their organization arrives in Peru, they embark on their biggest animal rescue challenge yet.

Katherine Connor and her children run an elephant sanctuary that rescues, rehabilitates, and re-wilds elephants from Thailand's tourism and logging industries. Now she wants to rescue an older elephant, Pang Fai, and release her from chains forever.

Chimp expert Estelle Raballand has formed an incredible bond with Ponso, a chimp who lives alone on an island and has been dubbed the loneliest chimp in the world. She's determined to find him a companion and thinks she has found the perfect match.

Sam Brittain and Melanie Croce run Seal Rescue Ireland, the only seal rescue in the entire country. Alongside devoted volunteers, they do everything to save and rehabilitate orphaned and injured seals so that they can return to the wild where they belong.

Cute Cumber, an orphaned baby dwarf pony with leg deformities, was saved by Ashely and her 3-year-old son, Deacon and brought to their home rescue, Twist of Fate Farm. Now, they are determined to find this fragile animal the perfect family.

Malkia, an orphaned baby elephant rescued in Kenya has been nursed back to health by her devoted keeper Julius at The Sheldrick Wildlife Trust. After two years of devoted care, she is finally strong enough to be reintroduced back into the wild.

Seven-year-old social media sensation Roman McConn and his mom, Jen, have saved over 1,500 shelter dogs by connecting them with adopters around the country. The duo have 1 month to find homes for over 100 shelter dogs, including Noah, Rocky and Migo.

Theresa and Tony “Scruff” Matthews turned their dream retirement home in Australia into a full-time kangaroo rescue. They’re ready to release kangaroos Lisa, Luna, and Barbie, but an injury might threaten one of them returning to the wild.

With the help of her two daughters and husband Phil, Donna Stepan runs Sleepy Burrow Wombat Sanctuary. She takes in a new orphaned baby in critical condition and the next 24 hours become a fight for its life.