Maintaining morale will be critical on the long journey to the Americas. Knowing where on the ocean you are is pretty important, too. The crew of the Perseus discuss.

The Perseus crew are on their way to the treasure island, the birthplace of the Hundred Tales, where they hope to locate the treasure box left behind by the Soyuz crew.

Suika and Ginro work together to rescue the mobile lab from the Perseus. Reunited with Senku and the others, the group works on items to help Kohaku with the selection process.

Amaryllis, Ginro and Kohaku are chosen to join the inner palace. The science team will need a way to communicate with them in secret, and, eventually, a way for them with the science team.

Senku and his companions finally set off for America in search of corn. However, a dispute arises between Ryusui and Senku shortly after they depart.

The morse code signal reading "WHY" saturates the airwaves too much for Ukyo to pinpoint a direction, so the Kingdom of Science works on a way to visualize the signal.

Moz and the Kingdom of Science form a tenuous, temporary alliance against Ibara. How long it will last is a question they can't afford to concern themselves with just yet.

Senku continues in trying to advance the Stone World, this time he makes "space food", it is in actuality cup noodles. After Senku finishes his project, Gen has an epiphany and devises a plan to take down Tsukasa's army without violence.

Kaseki's efforts to build the science vessel Perseus hit a roadblock when he realizes that it's impossible to get all the parts to fit in practice.

Amaryllis explains how she evaded petrification and how she came to her decision to sneak into the inner palace.

Stanley orders Luna to infiltrate the Perseus and identify Doctor Taiju. Things go sideways when it turns out to be a little too easy.

Senku does not trust the motivation of Shishio, so he will try to hide his plans from a new and unforeseen enemy for his plan to revive civilization.

Chrome and Magma struggle with Ukyo, while Senku, gets his hands busy with building up an invention; a new hope.

The final touches to the automobile are made and it is used to transport the science supplies to a fortified cliffside that's close to the Tsukasa empire. From there the automobile is upgraded into a tank, but unbeknownst to the rescue group preparations by the empire have been made to counter any vehicular attack.

While continuing to use the hot air balloon to search for the oil, it's decided that Ishigami Village needs to take up agriculture to prevent future food shortages, as well as to produce preserved food for their upcoming sea voyage.

Tensions rise as Dr. Xeno makes his introductions to the Perseus.

Shishio is determined to end Senku's life if he does not promise at that moment that he will abandon his idea of ​​recovering civilization as it was before the incident.

Hyoga is disarmed, but the kingdom of science is still in danger - Ishigami village is in flames! And Tsukasa will soon know that Senku is still alive... How will the villagers fight off the coming invasion?

The Kingdom of Science will need rations to last them through their voyage to the other side of the world. But Senku, being no professional, burns all the bread he attempts to bake.

More of the Kingdom of Science is brought back from petrification, but they are discovered in the cave by Moz.

The Kingdom of Science attacks and tries to execute their plan to steal the petrification device. Moz convinces Kirisame to use the device, but Ryusui's instincts tell him something is off about the situation.

With Senku still confined to the bed, Chrome's team begins work on the tunnel to Xeno's base.

Facing immediate danger from wild animals Senku and Taiju are forced to revive Tsukasa Shishio "The Strongest High School Primate". Although Tsukasa has tremendous fighting ability and provides abundant food as their hunter, their new ally harbors an opposing view on restoring humanity.

Kohaku shows Senku to her village, but it's going to take some convincing before they let him in. In the meantime, he makes friends with a like-minded, promising "sorcerer."

Kohaku's sister, village priestess Ruri, is gravely ill. Senku, Chrome and Kohaku begin their quest to make antibiotics to save her life.