Outlaw bikers fight cops and Chinese Triads to keep control of the crystal meth trade.

In Vancouver, a suburban gang war and heavy police presence drives some dealers and their customers to move downtown. But the cops are in hot pursuit.

Some call methamphetamine the "Devil's Drug." Often made in less than an hour from a common cold remedy, this powerful stimulant is sweeping across the U.S. and Asia. Follow a raid on a suspected meth lab, stake out a neighborhood pharmacy where addicts attempt to accumulate cold and flu pills, and meet a neuroscientist urgently searching for a cure for addiction. See the dangers of meth and the unexpected physical damages caused by the drug.

Known as Hillbilly Heroin, Opiate pain pills can be found in every town and city across the United States. From the poorest trailer home to the most expensive mansion, they are tearing apart the fabric of American society.

Known by users as the ultimate “love drug,” ecstasy’s euphoric high comes with major lows: Ravers have died from it and organized crime gangs will kill for it.

Deep in the Amazon, Rob—a former Wall Street broker turned healer—has created a free clinic of sorts, administering the highly potent narcotic ayahuasca to trauma patients.

Ketamine—chemically, a compound called ketamine hydrochloride—is a drug that was developed in the 1960s to sedate animals and humans for surgery, though it eventually was replaced by medications that worked faster with less risk. Beginning in the 1990s, initially to the puzzlement of police, burglars began breaking into veterinary clinics and stealing ketamine. They soon learned that recreational drug users had discovered ketamine and were turning it into the new hallucinogenic party drug. In its standard powdered form, ketamine looked like cocaine, and could be snorted in the same way. But it also could be easily modified for injecting, smoking or even mixing into drinks.

Inside the world of producers, traffickers, dealers, users, doctors, and cops who make up the multi-billion-dollar industry.

A former British gangster serves as guide into this illicit underworld, visiting a secret hash-making location nestled in the mountains.

For a few dollars, users can access dozens of compounds that mimic cocaine, ecstasy or marijuana. Sold as “Bath Salts” or “Spice,” these drugs are entirely legal.

Auto crime is the tip of a sinister global iceberg where a car stolen in LA could end up on the Russian black market or a truck taken in Laredo, Texas could become a heavily armored 'narco tank' used in Mexican Cartel gun battles.

The gambling mecca Sin City plays host to 40 million tourists a year. In storm drains beneath the Las Vegas strip, homeless addicts get high on crack in underground shanties, while in half-built suburbs, police battle marijuana gangs for control of the city's slump-hit homes.

New York City is in the grip of a heroin epidemic, as a new generation of middle-class suburbanite dealers hooked on prescription pills switch to heroin, and venture down the Long Island Expressway Â- dubbed the Heroin Highway into urban Brooklyn and Queens to get their fix.

Chicago, the biggest open-air crack and heroin market in America is at saturation point. The result: record levels of overdoses and homicides, as gangs fight over drug turf.

The supply chain of cocaine stretches around our world, bringing vast wealth to a few ... and misery to millions. Follow its trail through the eyes of peasant farmers producing cocaine paste, a trafficker tied to Mexican cartels and a 28-year-old crack dealer in Miami's poorest neighborhood. And literally see the true nature of cocaine addiction via revolutionary brain photography in a leading lab in Brookhaven, N.Y.

Heroin can be life threatening, claiming the lives of numerous victims. Follow this opium derivative as it begins in a remote Afghan heroin lab that processes the raw materials and then on to Chicago, where a dealer demonstrates its final preparation for street sale. Gain insight into its insidious powers from users, and witness a police raid on a heroin distribution network in New Jersey. Plus, go inside one radical attempt to combat heroin's social costs by supplying it free to addicts.

Cannabis is the most widely used illicit drug on the planet. To many, it's an evil weed, but to some, it's a sacred herb, even a lifesaver. For decades the global supply was controlled by criminals, but now a quasi-legal industry worth billions of dollars is booming. Visit growers who are leading a horticultural revolution, hear from users consuming for medicinal purposes, go inside the "Green Rush" of medical marijuana in cities across the U.S. and the violent marijuana cartels in Mexico.

Alaska has a dark secret : it has one of the biggest drug problems in America. We'll get a firsthand look at the effects of heroin and the withdrawal symptoms involved in using the drug.

In Hawaii, which has one of the highest rates of crystal meth users in the nation, National Geographic Channel cameras follow along on a raid to a drug trafficker's house to discover a woman who continues to deal crystal meth while her husband is in jail.

The devastating consequences of Hurricane Katrina in Louisiana resulted in a wave of small-scale drug dealers taking over the streets of New Orleans. As a means of coping with depression and post-traumatic stress disorder, traumatized locals have turned to cocaine.

Mexican and Canadian drug gangs compete for customers in the isolated terrain in Montana as officers patrol the vast region hoping to stem the tide.

Heroin, cocaine and prescription pills in plentiful supply makes Los Angeles one of the biggest drug distribution hubs in the U.S.

The local drug scene casts a dark shadow on the sunny lifestyle of Puerto Rico, a place where addicts roam the streets in search of their next fix. For Dr. Panelli, treating abusers for jungle rot,Â"a ghastly condition that comes with using injected drugs, can be an overwhelming task.

The most dangerous city in the USA, Detroit, is a perfect mark for today's growing drug industry. Dealers are learning cater to inner city clientele by selling smaller amounts of hard drugs like heroin and cocaine for single-digit prices.

Cocaine and marijuana drug fueled 24-hour lifestyle for Londoners.