Alaska has a dark secret : it has one of the biggest drug problems in America. We'll get a firsthand look at the effects of heroin and the withdrawal symptoms involved in using the drug.

In Hawaii, which has one of the highest rates of crystal meth users in the nation, National Geographic Channel cameras follow along on a raid to a drug trafficker's house to discover a woman who continues to deal crystal meth while her husband is in jail.

The devastating consequences of Hurricane Katrina in Louisiana resulted in a wave of small-scale drug dealers taking over the streets of New Orleans. As a means of coping with depression and post-traumatic stress disorder, traumatized locals have turned to cocaine.

Mexican and Canadian drug gangs compete for customers in the isolated terrain in Montana as officers patrol the vast region hoping to stem the tide.

Heroin, cocaine and prescription pills in plentiful supply makes Los Angeles one of the biggest drug distribution hubs in the U.S.

The local drug scene casts a dark shadow on the sunny lifestyle of Puerto Rico, a place where addicts roam the streets in search of their next fix. For Dr. Panelli, treating abusers for jungle rot,Â"a ghastly condition that comes with using injected drugs, can be an overwhelming task.

The most dangerous city in the USA, Detroit, is a perfect mark for today's growing drug industry. Dealers are learning cater to inner city clientele by selling smaller amounts of hard drugs like heroin and cocaine for single-digit prices.

Cocaine and marijuana drug fueled 24-hour lifestyle for Londoners.

See the underground world of drugs through the eyes of its makers. A former British gangster serves as guide into this illicit underworld, visiting a secret hash-making location nestled in the mountains. Check out growers in Holland who are leading a horticultural revolution in high-grade cannabis. Follow a batch of raw opium from an Afghan poppy field to an Iranian heroin lab. Follow the supply chain of cocaine through the eyes of Colombian peasant farmers producing the drug in a paste.

A look at the fight against the country's most dangerous dealers and the biggest producers. From smuggling at JFK International Airport to cartel kingpins in Arizona, U.S law enforcement is fighting the global trade

Behind the idyllic veneer of being one of the safest cities in the U.S, Salt Lake City is suffering from a massive drug epidemic. National Geographic pulls back the curtain and reveals the secret world of drug addiction in the Mormon community, the arrival of the cartels, and the dangers to the officers trying to control it.

After being rocked by a corruption scandal and a budget deficit in the range of 58 million dollars, the city's police department's staffing and morale are in bad shape. National Geographic follows an elite team of detectives who are trying to establish some control over the free for all drug market. Using their access to the dealers, users, and gang members at the heart of the problem NGC gives us a inside look at the drug infested city.

Washington, D.C., was once “Crack City” and the murder capital of the U.S. But an increased police presence following Sept. 11 made drugs scarce. In the neighborhoods of southeast D.C., one drug remained — PCP. And it's causing havoc. NGC goes inside the chaotic world of PCP where users think they're invincible and can be driven to insane acts of depravity. Visit the emergency room unit where doctors treat up to 80 psychotic patients high on PCP each month.

Portland's progressive attitudes have made it a mecca for America's homeless and they're helping fund the deadliest drug market in the Pacific Northwest. Here, pushers prey on the young, handing them free sample bags of narcotics to turn them into new customers. With thousands of Portland's youths succumbing to heroin's powerful allure, local police have made it their No. 1 priority to disrupt the flow into the city by smashing the local distribution networks.

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Molly, a powdered form of the drug MDMA, is exploding in popularity across the United States. Formerly marketed in pill form as Ecstasy, Molly is a total rebrand. Marketed as purer, cleaner and “without the additives,” this powder has become the most fashionable new drug for young people. But as the consumer demand for Molly has exploded, the production of pure MDMA has struggled to keep up with supply. As a result new, dangerous chemicals are finding their way into the market.

The southwest border of the U.S. is the main gateway for illegal drugs, and Dallas, Texas, is often the first port of call for the Mexican cartel drug trade. In this episode, witness how the Mexican cartels have tainted Dallas by turning it into their command and control center for the trade of their narcotics. Buyers desperate to get a hold of the cartel's high-quality product flock to Dallas from all over the country, giving local dealers the chance to make big money

Baltimore, a once prosperous city, lost many of its jobs along with its steel mills. In return, the city developed one of the biggest heroin problems in the country. For many of those that remain amid the poverty and abandoned homes, the “Heroin Hustle” is the way of life. One strip of Pennsylvania Avenue alone is estimated to take in $10 million a year from heroin sales. With the business booming, the heroin market is expanding outward to the suburbs, and the authorities are struggling to cope.

Dominican drug networks tied directly to the Mexican cartel are distributing countless amounts of narcotics in the historic city of Boston, fueling a widespread epidemic that law enforcement and emergency services can hardly contain. The Dominican drug organizations are increasingly using Puerto Rican dealers as their middlemen to flood the city with heroin. The epidemic touches all communities, making Boston one of the leading cities for heroin distribution.

A journey through the daily lives of drug crews in New York, Atlanta and Portland.

Heroin users in America began showing symptoms associated with Krokodil, a home-cooked opiate, including raw lesions, decaying skin and grotesque sores.

With more than 4 million regular users in the United States alone, cocaine has become worth more than gold. Join Nat Geo Channel as we go inside one of the largest markets in the country, Los Angeles, Calif.

The most powerful drug trafficking organization in the world, the Sinaloa Cartel, has found a new way to exploit American drug demand with Mexican super meth, a stronger and more addictive form of crystal meth.

The rapidly growing appetite for California Sour Diesel, a potent strain of marijuana said to induce an instant high, is helping fuel a violent drug underworld that stretches from coast to coast.