Alaska has a dark secret : it has one of the biggest drug problems in America. We'll get a firsthand look at the effects of heroin and the withdrawal symptoms involved in using the drug.

In Hawaii, which has one of the highest rates of crystal meth users in the nation, National Geographic Channel cameras follow along on a raid to a drug trafficker's house to discover a woman who continues to deal crystal meth while her husband is in jail.

The devastating consequences of Hurricane Katrina in Louisiana resulted in a wave of small-scale drug dealers taking over the streets of New Orleans. As a means of coping with depression and post-traumatic stress disorder, traumatized locals have turned to cocaine.

Mexican and Canadian drug gangs compete for customers in the isolated terrain in Montana as officers patrol the vast region hoping to stem the tide.

Heroin, cocaine and prescription pills in plentiful supply makes Los Angeles one of the biggest drug distribution hubs in the U.S.

The local drug scene casts a dark shadow on the sunny lifestyle of Puerto Rico, a place where addicts roam the streets in search of their next fix. For Dr. Panelli, treating abusers for jungle rot,Â"a ghastly condition that comes with using injected drugs, can be an overwhelming task.

The most dangerous city in the USA, Detroit, is a perfect mark for today's growing drug industry. Dealers are learning cater to inner city clientele by selling smaller amounts of hard drugs like heroin and cocaine for single-digit prices.

Cocaine and marijuana drug fueled 24-hour lifestyle for Londoners.

See the underground world of drugs through the eyes of its makers. A former British gangster serves as guide into this illicit underworld, visiting a secret hash-making location nestled in the mountains. Check out growers in Holland who are leading a horticultural revolution in high-grade cannabis. Follow a batch of raw opium from an Afghan poppy field to an Iranian heroin lab. Follow the supply chain of cocaine through the eyes of Colombian peasant farmers producing the drug in a paste.

A journey through the daily lives of drug crews in New York, Atlanta and Portland.

With more than 4 million regular users in the United States alone, cocaine has become worth more than gold. Join Nat Geo Channel as we go inside one of the largest markets in the country, Los Angeles, Calif.

As tourists flood New Orleans, so do drug dealers eager to make a profit; in a fierce competition one dealer becomes a target when he sells fake drugs.

The culture of cocaine is deeply entrenched on Wall Street and some will pay more than its worth for the purest quality available. It’s a buyer’s market and dealers must compete to deliver first and close the sale, while keeping up with the changing Wall Street appetite. A new generation of brokers and traders are turning to a drug that keeps them performing at work. And police are coming down on a drug that they regard as Wall Street’s dirty little secret — which is quickly turning into an epidemic.

The relationship between the million-dollar hip-hop industry and the billion-dollar drug industry; rappers in Calif. use drug money to pay for their studio time.

Delving into the Los Angeles porn industry, where a reputation for illegal drugs is under more scrutiny than ever after a number of HIV scares are changing the toleration of narcotics on set.

Thousands of students head to Cancun, Mexico for Spring Break and some have only one thing on there mind: to get wasted.

Enterprising inmates in two jails with tough drug policies, one in Calif. and the other in N.J., still find ways to get drugs inside.

As trafficking drugs through the Caribbean increases in preference to the land route across the Mexican border, gangs in the Dominican Republic have become a key players in the transhipment of cocaine.

Follow Detroit’s dealers, cops and feds as they take on the city’s wild rave scene in the frantic 48 hours leading up to Halloween. Anarchy rules the Motor City: Around the notorious 8 Mile Road, street slingers stock up and look for new opportunities downtown. In the suburbs, middle-class dealers bring party drugs to raves.

When Pittsburgh police crack down on heroin, they inadvertently open the door for wannabe dealers that see a chance to muscle their way into the market with a killer brand.

The side effects of drug use can be disastrous, but the people living in the world of the living dead fight an epic battle.

The drug of choice in Silicon Valley is cocaine, but a cop crackdown is pushing dealers and their programmer clients to meth.

From the DEA and dealers to users and doctors, Grim Reaper explores the deadliest drugs across the globe.

Heroin on Staten Island is reaching epidemic proportions as dealers from New Jersey take advantage of a crackdown on prescription pills that's leaving teenagers desperate for a soporific high.

Follow the rise in demand for narcotics during Mardi Gras, Spring Break, Independence Day, and New Years Eve, through the eyes of dealers, law enforcement and users