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A girl named Hannah has a weak immune system and had a heart transplant at only 11 days old. She has to take $1,000 medicine every day and that is what weakens her immune system. While the family vacations in San Diego, the team works hard to build a better home and environment for the Grinnan family. And surprise surprise! Lee Ann Womack performs at the end for the family!

Two boys, Paul and Kuran, were born to a crack-addicted mother. Lucy Ali adopted them as infants so she could give them a better life. As the boys were getting older, she decided it was time to expand the home. She gave a large sum of money to a contractor to add on, but he basically ran off with the money. Can EM:HE do what the con-artist didn't?

As a struggling widow of three daughters, Roseanne Dore is no stranger to hardship. The family was dealt a tremendous blow when their Kingston, Washington home, originally built by Roseanne and her husband, burned to the ground in March 2004. Following the devastating news of the fire, Roseanne found out that their home insurance policy lapsed when their agent retired. The structure was uninhabitable. While figuring out what to do, Roseanne moved her three daughters into a half-built, backyard utility shed that had no plumbing, electricity or running water.While living in the makeshift shelter, Roseanne's daughters - Jessica, 21, Sarah, 17 and Aariel, 13 -- went to friends' houses to shower. The entire family was stuck using an old doorless outhouse on the two-and-a-half acre property. One of the family's only wishes for their new home was to have indoor plumbing and bedrooms.When not cooking on an outdoor propane camp stove, these ladies took inside to the shed to prepare food. Desp

Martinez, CA - The Sears family are given an extreme makeover. In February 2004 the 17-year old Jhyrve was diagnosed with a rare gen related disease. The team builds the family a new and sterile house.

While design team leader Ty Pennington was preparing to film this episode in his hometown of Atlanta, he underwent emergency surgery for a perforated appendix. Although he was still recuperating, the energetic and dedicated Pennington did not want to let the family down. The episode incorporated his predicament into the show and captured how Ty was able to do his part from his hospital bed and later in the week, to participate in the reveal for the Harper Family from the Atlanta suburb of Lake City, Georgia. Patricia and Milton Harper worked hard and sacrificed for all the right reasons, but still could not achieve their dream of providing a real home for their children. After moving from the projects in Brooklyn, they wanted to give their sons Darius, 17, LaVaughn, 15, and seven-year-old Mister a safe haven to come home to every day. But the first-time homeowners didn't know they had just bought a big dump -- literally. Unaware of any problems when they purchased the home, the Harpers

In 2004 the mother of Charles, Michael, Sharis, Joshua og Jeremiah Higgins died of breast cancer. 2 months later their father died of heart complications. Then the Leomiti family, right next door, took them all in, but now they're eleven in total. Can the team give them more space?

Extreme Makeover: Home Edition designers and contractors came to the home of Doug Goodale, a veteran lobster fisherman and his family from Wells Harbor, Maine, with the remarkable news that, in just seven days, they will be able to move back into a finished and completely renovated house.Near the end of the lobstering season a few years ago, Doug Goodale made a decision that would change the lives of his family forever. Looking out at the stormy, choppy waters of Wells Harbor that day, he tried to decide whether to go out to sea or not. If he didn't go, he wouldn't make any money. Needing to provide for his family, he pushed his boat out into the water at dead low tide.When he reached his first trap and started pulling up his catch, a huge wave hit the boat, creating a slack in the rope which then spooled around the drum. A veteran fisherman, Doug knew to turn off the drum's motor and untangle the rope, but as he reached in to turn it off, the sleeve of his oilskin got caught i

A bachelor who raised his niece and nephew after his sister's sudden death has his house rebuilt.

In back to back episodes the design team heads to Virginia to help the Crawford Smiths, a family affected by multiple sclerosis. As well Actress-dancer Debi Allen pays a visit.

Sadie Holmes and her family of Altamonte Springs, FL, received the remarkable news that their hurricane damaged home will be renovated in seven days thanks to Extreme Makeover: Home Edition

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The Extreme Makeover: Home Edition design team travels to Bergenfield, New Jersey to build a brand new renovated home in seven days for a deserving family of six who have overcome some difficult disabilities. In order to better meet the Llanes family's unique needs, Academy Award-winning actress Marlee Matlin will serve as Team Leader.

The large Rogers family are well-known in their community for their selfless attitudes and strong morals. All the children excel in everything they do, whether it's sports or academics. Betsy was raised in a bi-racial family, and later married into a bi-racial marriage; as a result, she strives to teach her family and community about diversity and respect for others. A well known and much respected figure throughout the community, Betsy is a team mother for both the football and wrestling teams and a second mom to most of the kids in the area. She has passed her selfless values on to her children; her two eldest sons, Christopher and Jonathan, went on a two-week mission trip in Honduras to help build homes for those who live in worse conditions than even they could imagine.

David Gilliam simultaneously worked several jobs to support his family in order to fulfill his dream of becoming a firefighter and EMT. He was one state test away from getting his instructor coordinator license when he suddenly died. As a result of her husband’s autopsy, Maryann learned that the basement of her family’s home was contaminated with dangerous levels of toxic spores. Her doctor advised the mother and her six children to vacate the house for health reasons. The community has rallied around the Gilliams; since David’s death, the family have lived with several family members, neighbors and friends. Currently they are living with Maryann’s sister.

In early April 2006, a massive F-3 tornado tore through firefighter Jerrod Hawkins' hometown of Henderson, TN. While Jerrod was on duty and could only watch the storm from his fire station, the tornado hit his home directly, ripping the house from its foundation. Amy heroically saved her sons, Jair and Cole, by lying on top of them in the basement. But unfortunately the bricks, debris and concrete that hit Amy caused permanent injuries -- her vertebrae and ribs were crushed, her lungs were punctured, and she sustained serious head trauma. After the tornado subsided, Amy and the boys were found under a pile of rubble by neighbors who called the fire station, where Jerrod had to instruct his neighbors how to give his own wife CPR.

The Bliven family of Minot, North Dakota were told "Life's not fair" by their doctor upon learning their second child, Aaron, had cerebral palsy. The Blivens, who also have another son and daughter, treat Aaron like a "normal" kid. Aaron and his younger brother even played on the same Little League team. That is, until the recreation league decided Aaron's health was too much of a risk for the great American pastime. But instead of benching her young son, Michelle started a league of their own. "Dream Catchers" is a Little League team made up entirely of children with special needs. Michelle received the "Hometown Hero" Award for her tireless efforts in creating an environment in which EVERY child is special

Tama County, IA. The Kibe family are given an extreme makeover.

Brookings County, SD. The Thibodeau family are given an extreme makeover.

St. Meinrad, IN. The Farina family are given an extreme makeover. Despite her success in amassing funds for breast cancer, the Farina family's dreams of fixing up the old farmhouse are no longer plausible due to Shawna's increasing medical bills. The house contains no insulation for the long and cold winters, has a make-shift shower in their single bathroom and is missing three doors to the bedrooms. Now, with the help of Ty and the design team of Extreme Makeover: Home Edition, the Farina family will finally have a home they truly deserve, one in which Shawna can watch her children grow up, undefeated by her illness. While Ty and the designers, local builder Kerstiens Homes & Designs of Jasper, IN and hundreds of volunteers and workers are rebuilding their home, the Farina family will go on vacation to Walt Disney World.

Campbellsport, WI. The Koepke family are given an extreme makeover. Matt had dreams of renovating his home and finishing the renovations on the town Mill, but those plans were put on hold once he was diagnosed. He will be missed but never forgotten. Before Matt died, he had a chance to ask EMHE for one wish -- to take care of his family and give them the home they deserved. While the Ty and the Extreme Makeover: Home Edition design team, local builder Monarch Homes, contractors and hundreds of workers and volunteers remember Matt's dreams and work together to transform the Koepke house into a dream home in a remarkable seven days, the family will go on vacation to San Diego.

Logan, UT. The Pauni family are given an extreme makeover. When Janet and Danny left the island of Tonga in 1991, it was to give their family a better life and a better education. Danny was the strong leader in this family and the glue that held them together. That's why it was as if a bomb had hit when he suddenly died in May of 2004 from a heart attack, leaving Janet a widowed mother of nine (eight children and one nephew living in the home). With no life insurance policy and the sole provider gone, this tight knit family has been struggling both emotionally and financially. While the Extreme Makeover: Home Edition design team, local builder Kartchner Homes of Logan, Utah, and hundreds of workers and volunteers are transforming the Pauni's house into a dream home, the family will vacation in a private yacht in the British Virgin Islands.

Redondo Beach, CA. The Ripatti family are given an extreme makeover. Husband and wife Tim and Kristina worked together as police officers in the gang division of the LAPD. They met on the job and are married, with baby daughter, Jordan. Despite the extreme dangers of their jobs, Kristina and Tim are both happy and proud to serve and protect their community. But just how dangerous their jobs could be became terrifyingly clear this past summer. One night Kristina and her partner followed a man who was acting suspiciously. When he started to run, they pursued him on foot. Kristina caught up to him, but then he shot her. Her partner in turn shot and killed the gang member and called for help. Over the radio Tim heard that an officer had been shot, and he immediately rushed to the scene to find his wife fighting for her life. Kristina survived the incident, but today is paralyzed from the chest down.

Lincoln, NE. The Fullerton-Machacek family are given an extreme makeover. This loving family of seven love spending time together, but it's difficult since they still live separately. They split time between Kenny's cramped house and Theresa's even more cramped apartment. Kenny and Theresa want to be married and to finally be united under one roof, but the condition of Kenny's home has made it difficult to be sold. The three-bedroom, one-bathroom home is over a hundred years old and unsafe. Currently the two basement walls are buckling, the refrigerator isn't working and there's a leak in their only bathroom that they cannot afford to fix

Chicago, IL. The Noyola family are given an extreme makeover. While Ty and the designers, local builder Norcon Inc., and hundreds of volunteers and workers are rebuilding their home as well as revamping their grandmother's home, the Noyola family will go on vacation to Walt Disney World