The team must track down two assailants who wear animal masks while committing armed robberies, with the latest leaving an off-duty 26 Fed security guard dead. Also, Tiffany and Scola butt heads on whether or not to accept the local NYPD’s offer to help in the investigation.

The team rushes to track down two doctors abducted by a desperate father willing to do anything to save his son. Also, Jubal's uncertainty in his family life affects his judgement during the hostage situation.

While investigating a mass casualty incident at a New York City restaurant, the team scrambles to determine if it was racially motivated and if there was more than one gunman. Also, Maggie starts to notice troubling behavior from her co-worker, Elise.

The team welcomes a new member, Special Agent Tiffany Wallace, as they search for killers who orchestrated a mass shooting at a media company, and OA’s personal connection with the case threatens to cloud his judgement.

The team must infiltrate a drug trafficking gang after the robbery of a chemical plant leaves two customs agents dead. Also, Nestor offers his help on the case, giving Maggie new insight into his character.

When a political reporter is kidnapped and held without a ransom demand, the team must dig into her past relationships in order to pin down her assailant’s motive. Also, Isobel’s relationship comes under fire when the case makes a connection to her boyfriend, Ethan.

When the CEO of a major brokerage firm is shot and killed while surrounded by protesters, the team looks into who had the most to lose from his company's perceived manipulations. Also, Scola's previous Wall Street career and the reasons he left come to light as the financial details of the case begin to unfold.

When five prominent men are killed at a trendy New York City restaurant, the team’s investigation brings them into contact with a lieutenant in Antonio Vargas’ cartel, triggering a long-awaited showdown between Isobel and Vargas.

The team races to stop an active serial killer after three women are found weighted down at the bottom of a lake, and Jubal looks into an old closed case after there are multiple similarities to the recent victims.

When a passenger train is hijacked and rerouted while at high speed with an unarmed OA and Gemma on board, the team races to wrest control away from the unhinged perpetrators and prevent a catastrophe.

Maggie and Dana struggle to find justice for victims murdered by a serial killer who left a ghoulish mark on all of his victims, while the mayor limits the investigation in order to prevent economical loss.

As the team searches for a young girl who was kidnapped from a cabin during a family vacation, they discover that the abduction may be tied to a skeleton in her family's closet. Also, Maggie questions her relationship with Nestor when she learns he hasn't been completely honest with her.

After Rina is critically wounded while heading to work with Jubal, the team makes the chilling discovery that a vengeful Vargas orchestrated the shooting from behind bars and continues to target the rest of their team and their loved ones.

A woman with information about the death of Maggie’s husband is abducted, leading OA and the team to uncover a criminal operation larger than anyone imagined. Also, Dana puts her career in jeopardy when she stands by and allows Maggie to work on this case that has such a personal connection to her.

A car crash results in the death of a photographer; Maggie sympathizes with his widow when she notices similarities with her own husband's death.

After a truck filled with armour-piercing rifles is hijacked, the team works to discover who stole it, and what they have planned for the stolen weapons. A friend from OA's past returns to help with the case, but OA isn't sure he can trust him.

After the police ignore a desperate father's plea for help, he abducts a billionaire's daughter and holds her hostage in a near-impenetrable safe room until his own missing child is returned to him. Also, Jubal puts his hostage negotiation skills to the test.

Jess LaCroix and his team come to help OA find a fugitive LaCroix arrested years ago after a bus with 26 students goes missing and he's the main suspect. The crossover continues on FBI: Most Wanted S01E09 Reveille (II).

The FBI team investigates a drug deal gone bad after the body of a college student is found. Also, Detective Hailey Upton temporarily joins the team and finds her usual investigative methods clash with the Bureau's more buttoned-up environment.

When the leader of a drug cartel and one of the world's most wanted men, Antonio Vargas, is apprehended by the team, the entire FBI headquarters is put at risk when his henchmen unveil a terroristic threat to free him. During the turmoil, Isobel must make the difficult decision whether to sacrifice her conscience or her career.

After a bomb leaves three people dead, the team presses a reluctant informant to gather information from his close friends who are under suspicion. Also, OA finds tension in his relationship with his girlfriend, Mona, when they clash on where the informant’s rights lie.

After a young woman is killed on her way home from a lavish yacht party, the team investigates who she was and how she came to be at the event, which was attended by some of the most influential people in the world. Also, Maggie brings Crosby into the investigation after a murder suspect is identified as a veteran who had been on several Army operations with Crosby. The crossover continues on FBI: Most Wanted S03E01 Exposed (II) and FBI: International S01E01 Pilot (III).

When a young couple is found murdered in a New York City park after returning from vacation, the team searches for a suspect linked to the drug trade. Also, Scola turns over a new leaf when it comes to his relationships.

OA is forced to confront one of his biggest fears when the team discovers that deadly sarin gas may have been sold to terrorists.

The murder of a TSA agent leads the team to hunt down a killer who is using drug mules to exploit airport security checkpoints. Also, OA struggles to cope with the aftermath of the sarin gas exposure and the 10th anniversary of his army friend's death in Afghanistan.