A woman with information about the death of Maggie’s husband is abducted, leading OA and the team to uncover a criminal operation larger than anyone imagined. Also, Dana puts her career in jeopardy when she stands by and allows Maggie to work on this case that has such a personal connection to her.

The team must track down two assailants who wear animal masks while committing armed robberies, with the latest leaving an off-duty 26 Fed security guard dead. Also, Tiffany and Scola butt heads on whether or not to accept the local NYPD’s offer to help in the investigation.

The team rushes to track down two doctors abducted by a desperate father willing to do anything to save his son. Also, Jubal's uncertainty in his family life affects his judgement during the hostage situation.

After a young woman is killed on her way home from a lavish yacht party, the team investigates who she was and how she came to be at the event, which was attended by some of the most influential people in the world. Also, Maggie brings Crosby into the investigation after a murder suspect is identified as a veteran who had been on several Army operations with Crosby. The crossover continues on FBI: Most Wanted S03E01 Exposed (II) and FBI: International S01E01 Pilot (III).

When an officer is shot dead at a pawn shop along with the store’s owner, the team tries to figure out why a young, recent Ivy League dropout is tied to the crime.

The abduction of a young woman leads the team back to a cold case from 18 years ago, which pushes Isobel to reconnect with her old partner Jake and take another shot at solving one of her first cases in the bureau.

After a mysterious bioweapon leaves two MTA workers dead and one injured, the team rushes to determine who is behind the attack and the location of their next target; Jubal’s past demons begin to surface.

An American diplomat is killed while being used as a pawn in a dangerous drug ring, and the team must work together to bring them down. Also, Jubal and OA try to help friends from their past fight off their inner demons.

When a controversial senior leader from Egypt comes to New York for a heart transplant, OA struggles to balance his personal opinion with his professional duty when he is assigned to the security detail.

After a decorated FBI agent is murdered, the team investigates and uncovers the man led a double life. Also, Maggie struggles with what information she should reveal to the agent’s widow, who is also her personal friend.

While investigating a mass casualty incident at a New York City restaurant, the team scrambles to determine if it was racially motivated and if there was more than one gunman. Also, Maggie starts to notice troubling behavior from her co-worker, Elise.

When the deputy commander of an Air National Guard Base is kidnapped and forced to give over access codes, the team must work quickly to find the suspect along with stolen ammunition. Also, Scola questions his own safety in the aftermath of a recent traumatic experience.

When a trucker is gunned down after a routine trip from Canada, all signs point the team to a noted criminal on the FBI’s Most Wanted Terrorists list. Also, Jubal gets to work with an old friend and colleague, Detective Jack Lombardo.

After Jubal narrowly escapes a calculated assault on a secret FBI office, the team discovers a rogue terrorist group has infiltrated the FBI. Unsure of who to trust, the team must work in the shadows to unmask the culprits threatening the sanctity of the New York field office.

When an alt-right provocateur is murdered after giving a speech at a university in New York City, Maggie and OA investigate the school's more extreme political groups and rely on OA's sister, Amira, a student, for help.

Maggie, OA and the team must stop a hacker who is disabling life-saving equipment in several New York City hospitals. Jubal's son waits for important surgery at one of the impacted hospitals.

OA is forced to confront one of his biggest fears when the team discovers that deadly sarin gas may have been sold to terrorists.

The murder of a TSA agent leads the team to hunt down a killer who is using drug mules to exploit airport security checkpoints. Also, OA struggles to cope with the aftermath of the sarin gas exposure and the 10th anniversary of his army friend's death in Afghanistan.

The team pivots when their sting operation to secure a massive bomb from an illegal broker leads them to discover that the device is already in the wrong hands. Also, Jubal’s promise to be present at his son’s birthday party is put to the test as the case continues to heat up.

After a Wall Street investor is murdered, the team is led to an insider-trading ring that uses unconventional methods to gain information. OA struggles to maintain confidence in his budding relationship with Mona.

When a board member of a soon-to-be-public medical tech company is murdered, the team tries to find out who had the most to gain from his death. OA is conflicted when pressure to help a family member is at odds with his commitment to tell the truth.

A car crash results in the death of a photographer; Maggie sympathizes with his widow when she notices similarities with her own husband's death.

After an altercation with a student, a teacher goes missing, leading the team to investigate everyone who might have had a grudge against him. Also, a key witness in the case steps up to help, and Maggie does whatever she can to ensure their safety.

A former kidnapping victim is linked to a series of murders that includes the daughter of an NYPD detective. Also, Kristen begins to doubt her ability as an agent after a training exercise leaves her shaken.

A bank holdup leads the team to a safe deposit box, the contents of which have the potential to destroy national security; Kristen is eager to get back into field work while other team members still have their concerns.