In Casey's bid to become president of Zeta Beta Zeta, she tries to win over her sorority pledges by throwing a slumber party that turns scary when the lights go out. Meanwhile, the same stormy night at Cyprus Rhodes University brings trouble for Cappie when he gets an unexpected visit from a beautiful and mysterious girl named Destiny.

When Frannie challenges the sisterhood of ZBZ girls, and Casey retaliates by challenging the IKI’s to a game of dodgeball. Meanwhile, Rusty struggles with the fact that Dale is so in love with their new apartment that he never leaves, so Rusty enlists the Kappa Tau’s to invade the house to scare him away. But the plan backfires when the landlord shows up the next morning with a tour.

It's the first week of school and the first week of rush and neither is going particularly well for Rusty. On his very first night trying to become one with his pledge brothers, he fell asleep on the job. His "brothers" let him know they weren't too happy by leaving Rusty to dash off to class sans shoes, with blue feet and covered in mud. Rusty's professor was not amused.

It's mating season and no one seems to be having a good time. Rusty has to come up with a date for a Kappa Tau party but since just talking to a girl turns him into a blithering idiot, it's going to be hard to convince someone he's appealing. So he turns to Casey for help.

Allies become enemies when both Casey and Frannie are nominated for the title of Omega Chi Sweetheart. Who will prevail in this the ultimate cat fight? Meanwhile, as Rusty's relationship with Jen K. heats up, he longs for more private time with her but his judgmental roommate Dale is always around, making it difficult for the two lovebirds to spend time alone.

Rusty and Casey return to CRU but must contend with the backlash from Jen K's story, and deal with the fallout from their relationships. Meanwhile, Cappie and Rebecca must make a choice about their relationship.

Omega Chi becomes the victim of Kappa Tau's pranks when Cappie seeks to get even with Evan for blowing the whistle on their recent underground festivities. Meanwhile, Casey's rivalry with Rebecca intensifies when she learns about Rebecca's new relationship.

Couples are coming together. Couples are splitting apart. There’s Casey and Ashleigh—best friends and sorority sisters since freshman year, now they’re on the outs. Lack of support—Casey for Ashleigh—is the issue. But someone’s waiting in the wings to show Ashleigh she can be a friend, and that someone is Rebecca.

Casey seems to have it all - she's in the best sorority, has the most popular boyfriend, and is in-line to become the next President of her sorority that is until her dorky brother, Rusty, comes to school and is determined to join a fraternity.

Everyone is asked to suit up and pick sides as Kappa Tau and Omega Chi go head to head in floor hockey. But that’s not as easy as it looks. Casey is rooting for Evan and Omega Chi, naturally. So much so that she sets Cappie up for a fall. But did she do it to help her man or to get back at Rebecca? Because Casey and Rebecca may be “sisters” but they sure don’t play like a team. When Rebecca learns that Casey of “Casey and Evan” was formerly with Cappie, she uses the info to backstab Casey and get herself promoted to ZBZ’s head of Athletic Support. That’s when Casey shows what she’s made of—no one is going to beat her.

Rusty, Dale and Dana are hanging out together and Dana suggests throwing a murder mystery dinner party to help Dale socialize. Members of Omega Chi Delta then storm in and take Dale away as he‘s pledged to them. Casey gets a surprise visit one night from Ashleigh, who has lost her job in New York and now plans to stay back at the house. Calvin reveals that he has no major, just like Cappie, but wants to keep it a secret. Meanwhile, Rusty worries that Dale is joining Omega Chi to get back at him, so he devises a plan to get Dale membership into Kappa Tau. But Dale is insulted by Rusty‘s insistence, and goes to Omega Chi‘s hazing anyway. While he‘s there, Rusty and his friends kidnap him and take him to Dana‘s murder mystery party, inadvertently leaving Spidey there to face the Omegas‘ wrath. Dale eventually leaves Rusty‘s party, claiming that he wants to be a part of that fraternity, and that Rusty should care about his own pledge Spidey instead. Casey is having a hard time finding a study group to join in her new law class because of her controversial past. Ashleigh reveals that she actually ran away from her job because she couldn‘t handle it. Katherine (Nora Kirkpatrick) returns to attend CRU Law school.

Spring Break is almost here, Cappie gets his pledges to practice with their fake ID's, leading Rusty into a tricky situation. Meanwhile, Casey goes to Evan for help with her LSAT test and in the process she begins to question her future.

The students enjoy spring break on the beach. Cappie and Casey explore their new friendship at a time when Rebecca needs Cappie's attention. Evan looks to move on and escape his feelings and ends up with a familiar person. Rusty returns to school and on his way back he reunites with old friends.

Season 2 begins with the annual Greek Week competition. Despite their opposing houses, Calvin and Rusty strive to remain friends. Meanwhile, Casey has to decide what to do about Rebecca's actions over spring break, and Rebecca's continuous bad behavior doesn't do the situation any good.

Troubled by the recent discovery that Andy hooked up with Jordan, Rusty is hesitant to take Andy on as his little brother. Will Rusty be able to get past the budding relationship to become the big brother Cappie has been to him? When Cappie hears of Rusty’s reluctance, he takes Rusty aside to remind him that he brought Andy as a pledge to the fraternity and it is his responsibility to be the best Big Brother that Rusty can be for him. Meanwhile, when Evan’s real-life brother, Patrick, comes for a visit, their celebration at Dobler’s is interrupted by Cappie and the three end up reminiscing about their old camp days. But later Patrick shocks and disappoints Evan by asking for money. Frustrated by his brother’s actions, Evan takes it out on Frannie. When Casey and Rebecca believe that the thief responsible for stealing the ZBZ food supply is Fisher, they can’t figure out why Ashleigh won’t accept it. But when they dig a little further, Ashleigh reveals the delicious truth.

As mid-term week approaches, the pressure is building for Rusty as he is determined to maintain his grades while keeping up his social life at the fraternity. Of course, Cappie has the answers for him but is it the right thing to do? Cappie not only presents Rusty with an appealing offer of help but when he is partnered with Casey on a school project, Casey is tempted once again by her past.

When the ZBZ girls express their desire to reunite with the Omega Chi's, Casey is put in a position of having to face her past relationship with Evan head on, causing her to come to grips with her feelings about him. Meanwhile, Rusty has a new crush and oddly enough it is Dale who helps him get a date with the girl. However, since Rusty has only had one relationship in the past, his eagerness to find someone new just might backfire.

The ZBZ girls throw a crazy competition among themselves as they each coach a different fraternity in a series of games. Casey coaches the Lambda Sigs and ends up developing a crush on one of the fraternity brothers. Meanwhile Rebecca tries to coach the Kappa Tau's and, at the sometime tests her relationship with Cappie.

Trouble is caused by Casey when she bends the sorority house rules for Ashleigh. Cappie tries to get rid of restrictions. Meanwhile, Rusty finds himself attracted to Tina, the girl who wants to take down the Greek system.

Casey and Ashleigh discover that they have the same crush for the ZBZ Crush Party. Meanwhile, Rusty meets his new RA and turns to him for help.

Now a sophomore, Rusty gets to participate in Rush Week for the first time and he is determined to land Andy as a pledge for Kappa Tau, but Calvin feels the pressure from Evan to get Andy to pledge Omega Chi. Who will prevail in the battle for the big man on campus? Ashleigh and Casey start to doubt Rebecca's "mole" abilities and begin to question whether she's actually a double-agent for Frannie's new sorority when the ZBZ girls’ rush week “Project Runway” fashion skit is successfully sabotaged by Frannie.

The KTs race to return a stash of stolen campus goods, hoping not to get caught by security. Elsewhere, Casey sneaks Max into a faculty party so he can meet a visiting professor that needs an intern, and Ashleigh considers taking her relationship with Fisher public.

Cappie turns to Rusty for his brain power when the volcano for Kappa Tau's legendary Mt. Vesuvius party fails to erupt. Meanwhile, Casey and Evan are back on track as he introduces her to his powerful parents over dinner. But an unexpected appearance by Rebecca, a Senator's daughter, instantly bonds her to Evan's parents, leaving Casey to feel like an outsider with this blue-blood clan.

Kappa Tau and Omega Chi face off in an epic battle of practical jokes complete with waterguns, duct tape and farm animals. Rusty tries to mediate the situation to save his friendship with Calvin but finds it only escalates the rivalry. Meanwhile, Casey learns that the only way to rid ZBZ of Lizzi, the conservative national rep overseeing them, is to forgive Frannie and reinstate her in a "diamond" ceremony.

Casey finds out about Rebecca and Fischer's secret kiss, but when Rebecca confesses to Ashleigh, she outs Casey for keeping it a secret. When Mr. Cartwright, Mr. Howard, and Mr. Logan arrive for Father-Daughter weekend at ZBZ, they find out about their daughters' feud, and it reflects upon their weekend behavior. At the same event, Rusty gets nervous about meeting Jordan's father. Meanwhile, in an effort to get over their lost loves, Dale and Cappie fawn over the same girl, but they both ultimately get rejected.