Season 1

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  7.9/10269 votes

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  Chapter 1: LSD

  Season 1 Episode 1 - Aired 7/12/2022

  From its 1943 origins to today's microdosing trend, LSD has been expanding minds and changing lives with the help of counterculture gurus — and the CIA.

  Director: Lucy Walker

  Writer: N/A

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  8.2/10225 votes

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  Chapter 2: Psilocybin

  Season 1 Episode 2 - Aired 7/12/2022

  Magic mushrooms, long considered sacred by the Indigenous Mazatec in Mexico, become the subject of scientific studies measuring their intense effects.

  Director: Lucy Walker, Alison Ellwood

  Writer: N/A

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  7.7/10183 votes

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  Chapter 3: MDMA

  Season 1 Episode 3 - Aired 7/12/2022

  Championed by both therapists and ravers, ecstasy stands out as the first psychedelic likely to become legalized, thanks to passionate advocates.

  Director: Lucy Walker, Alison Ellwood

  Writer: N/A

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  7.0/10161 votes

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  Chapter 4: Mescaline

  Season 1 Episode 4 - Aired 7/12/2022

  Mescaline, the psychoactive molecule in San Pedro and peyote cacti, a sacred medicine that Native Americans have had to fight for the right to use.

  Director: Lucy Walker, Alison Ellwood

  Writer: N/A