I.R. is jealous of I.M. Weasel (I.M. being the first on Mars, Jupiter and Uranus). But then NASA tells I.R. that he can become the first on the sun, and I.R. readily accepts the job. This creates quite the challenge for I.M...

Weasel and I.R. investigate the crime of who is erasing the characters from Cow & Chicken.

The director of Weasel and I.R.'s cartoons does nothing but stealing old clichés from classic cartoons.

Weasel is going to face a human in a ping-pong duel. A jealous I.R. tells the human that he's won a trip, so I.R. can duel Weasel himself. But as I.R realizes that he doesn't stand a chance, he resorts to cheating.

While Weasel is trying to cure an athlete's face patient, I.R. Baboon creates a cure which goes wrong and spreads it over the town.

I.R. is in charge on making a bridge from the U.S. to France, but when Weasel takes over, I.R. vows for revenge.

An accident causes Weasel and I.R. to drop their brains.These get swapped while being unconscious.

Weasel and Baboon are a pair of friendly vampires who drink only canned blood and are just looking for a fun little night on the town in Pantsylvania. But someone should try telling that to the vampire hunter Dr. von Smellstein, who's out to get our heroes!

Weasel tells his story to psiquiatrist Sigmund Fraud about his mishaps with I.R., at the same time I.R. is telling his own mishaps with Weasel in the room next door.

A narrator tells the story about the travelling country-singing duo of Weasel and Baboon.

I.R. has his own ""Deep Sea Tour"" company, which takes people to the bottom of the sea.

It's Christmas, and I.R.'s family pays a visit. But when they go to Weasel's house instead, I.R. vows to ruin Christmas.

In ancient Egipt, Weasel and I.R. must save the queen from a huge group of snakes.

I.R. will do anything to get Weasel's role on his last movie.

Weasel and I.R. create their forms of life.

I.R. hurts himself while walking up to Weasel's house! Weasel discovers that I.R. has broken his phantom foot! When I.R. goes to see Dr Clearbottom on phantom limbs, this doc's services are at a very high price! Weasel later reveals that it was Clearbottom who dug the hole which injured I.R.'s phantom foot so he can take all his money!

Weasel investigates the strange habits of I.R., who keeps changing his habitat due to unknown reasons.

I.R. discovers that he has magical paws granting all awful wishes.

It's discovered that I.R. is the king of the kingdom of Yurp, so Weasel must turn him into a gentleman.

I.R. destroys the Law of Gravity (literally), which causes all lawyers to float (since they are the only ones that understand law).

I.R. finds an abandoned baby and adopts him as his son.

Cow selfishly wants Weasel for herself so she fishes him out of the tv with a pie! But I.R. becomes very lonely without Weasel.

While working on a supermarket, Weasel meets a smart banana with the ability of speaking.

Weasel creates a time machine that I.R. uses to go back in time, but Weasel discovers that I.R. is destined to solve all kind of problems at certain periods.

Weasel and I.R. travel to the Moon to create a new form of living, through oxygen, cities and plants.