Raised in Northern California, Kenny excelled in football and had big dreams of playing in the NFL, but a misstep in high school triggered a series of events that left him homeless and addicted to dangerous amounts of fentanyl.

When Christine's brother died in a tragic accident, she turned to methamphetamine and her seemingly perfect family spiraled out of control; interventionists Ken Seeley and Sylvia Parsons team up on the biggest case of their careers.

Despite multiple overdoses and medical emergencies, Christine and her three adult children continue to use dangerous amounts of fentanyl together in their single studio apartment in Garden Grove, Calif.

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Amber Rose travels home to South Philadelphia to come to the aid of her childhood best friend Tina, who's addicted to fentanyl and crack. But first, she must find her.