Jackie and Jade have different goals after learning the Dark Hand members have stolen an endangered tortoise, which has the Rabbit talisman of super speed encrusted on its shell. And now, the Dark Hand must try to get it out, and Jackie must obtain the talisman and the tortoise before it becomes someone's dinner.

After having a fight with Shendu, Valmont keeps the Dragon Talisman of combustion for himself and not only busts into the U.S. Mint but puts Captain Black into the hospital as well. Valmont steals all the gold in the reserve, and Jackie must get the talisman, but this time, he has to use his brain to defeat Valmont because of Valmont's incredible powers.

Captain Black hires Jackie Chan to a secret government agency - Section 13, to track down the artifacts pursued by the Dark Hand, a crime organization far darker than anyone could have known. Also, Jackie's 11-year-old niece came to visit from Hong Kong and finds herself willing to help in the fight against evil. Jackie must gather up all 12 magical talismans that the Dark Hand had started retrieving before the Dark Hand does.

Jackie and Jade set out to find the Snake Talisman in a cave in South America. They cross paths with an egotistical "archaeologist" shooting for a TV show. After catching wind of their quest the "archaeologist" steals the Talisman. Things become more complicated after the Dark Hand shows up.

The museum asks Jackie to help someone who claims to have made a major discovery in the arctic circle.

Jade accidentally drops the Rat Talisman into the battery compartment of her Gnomekop toy, and it comes alive through the power of reanimation. The toy is grabbed by the Dark Hand and is used to get to Section 13. Jade and Jackie must track the toy down.

Jackie and company stop in ghost town. They find a book with the story of Jackie's ancestor who was a sheriff in the Old West.

Jade befriends the boy king of Tangra when he comes to visit, and uses the Snake Talisman to get out for some much-needed fun. Unfortunately, this falls right into a plot to kidnap the young king and hold him for ransom.

Drago breaks out of Section 13 on a mission to absorb the demon chi that is held in the original artifacts used to defeat the demons so many years ago. He finds the Enforcers at a petting zoo and transforms them into dragon-human hybrids. Drago locates the fan that holds the chi of the Wind Demon. Meanwhile, Jade gets into the nasty habit of burping. Jackie and Captain Black hunt Drago down to a Chinese-themed car wash, where the fan is located. Unbeknownst to everyone, Jade absorbs the demon chi. At school, her burps create powerful wind storms, and she begins to transform into a frog. Drago attacks Jade at school in order to absorb the chi, but Uncle and Tohru arrive to capture it instead. Drago fires the Enforcers and turns them back into their old human selves after they prove that they are weak and useless.

Uncle has fashioned a locater for the activated relics. As Jade watched a game show called, ""The International Island Challenge,"" the locater senses the next relic, which is the prize on the game show: the gourd containing the Water Demon's chi. Jade pleads Jackie to let them enter the contest held on Boru Island, but Jackie explains that this is a serious mission. However, on the set, the producer mistakes Jackie, Uncle, Jade, and Tohru as a competing family. They must face off against the Dusseldorf family, but they fail in the first task when Tohru falls off the bridge after being pelted by coconuts. However, it is Uncle who is voted out of the family, but he manages to stay on the island for the night after complaining about his supposed fear of flying. In the second round, neither family wins the bug-eating contest, so they must race in the tie-breaking round. When Jackie, Tohru, and Jade near the finish line, Drago appears, manages to obtain the Water Demon chi, and creates a tid

Jade's hopes of a birthday celebration are dashed when Drago's failed attempt at stealing the recovered two demon chis puts everyone on high alert at Section 13. The postponement of her birthday continues when two demons' chis, earth and moon, are activated within the same day. It is a race against time as Jackie, Uncle, Tohru, and Jade attempt to stop Drago, his new henchmen, Strikemaster Ice and his gang from acquiring the power of the two chis.

The Enforcers are released from prison and are required to finish off their sentence by doing community service. Jackie begins tailing them, watching their every move. They have become suspects in his investigation into the failed attempt by three unknown assailants to steal the valuable golden squid, which is being showcased at the museum. Meanwhile, Jade who quit the buttercup scouts due to sheer boredom has joined the dragon scouts in a quest for more adventure and excitement. Jade becomes very suspicious of three specific members of the scouts when she and Jackie discover that they are the nephews of the Enforcers. She begins following and watching them, hoping to catch the three kids doing something illegal.

After capturing the chi of Hsi Wu, the sky demon, Uncle attempts to place it in the chi containment unit. However it is broken, so the chi must remain in the chi-o-matic. Thinking that it is empty, Jade then takes Uncle's chi contraption with her on a school field trip to a haunted doorknob museum. Jade's teacher, Mrs. Hartman confiscates the chi-o-matic and accidentally infuses herself with Hsi Wu's chi. Things get worse in the haunted house when Drago appears and the ghosts get angry at the presence of two demons in their house.

Jackie and the gang visit the ancestral home of the Chans in China (now mostly underwater). There, they accidentally release three demon spirits that transform their bodies into the physical embodiment of their fears.

The Demon Chi briefly escapes from the Containment Unit. All of them are retrieved, except for the Earth Demon chi, which flees Section 13 and inhabits the body of one of Jades' Friends Larry (a comic book nerd, who also loves Super Moose) who proceeds to use his new demon powers for good as the superhero Spectacularry. Unfortunately he causes more problems than he solves. To prevent Draco obtaining the Earth demon Chi Jackie, Jade and Uncle Head to where any comic nerd with super powers would go, a comic fair. But the Demon Chi is slowly overwhelm Larry's good nature and with Drago closing in, Jackie, Jade and Uncle must save Larry before his super heroics destroy all around him.

Tchang Zu's demon chi is located in the ruins of the Titanic. Jackie, Jade, Tohru, and Uncle, ridden with the flu, journey into the murky depths of the wreck to find it, but Drago has followed them. Things aren't helped when Jackie suffers from being down in the cold water for too long and he loses all grip of his senses...

After fully absorbing the chi of Tchang Zu, Drago sets out to magnify the power of the thunder chi by turning his new lair, Seattle’s Space Needle into his own personal electrical rod. Uncle reveals that the longer that Drago has the demon chi, it will become even more difficult for him to remove it.

The chi of the mountain demon, Po Kong is released after Tohru has a midnight snack whilst on a diet.

A dark Chi-Wizard from the future called Iso travels to the past to steal one half of an ancient relic from Section 13. Unbeknownst to Iso, Jade follows him through a time portal on his return trip to the future and runs into her older self. Young Jade is shocked and disappointed to learn that adult Jade has so easily accepted the punishment of being demoted from field agent to desk duty at Section 13.

Drago succeeds in capturing Jackie, Uncle, and Captain Black. He holds them for ransom in order to get the prize that he so desperately wants, the Chi containment unit. With the lives of their loved ones hanging in the balance, Jade and Tohru confront Drago and turn to an old enemy for research. It appears that Jade and Tohru aren't the only ones hoping to double-cross the son of Shendu.

Captain Black, the J-Team, and some old adversaries put their differences aside to come together in order to stop Drago who is on the verge of conquering the entire world.

Tohru's mother comes to visit him and clashes with Uncle. Meanwhile, Tohru is almost seduced by a rival gang, the Black Hand to return to crime and help them steal the statue of the Golden Octopus.

While exploring some Pyramids in Mexico, Jackie gets a call from El Toro. He needs Jackie's help dealing with the legendary El Chupacabra.

The Dark Hand seeks out the next Demon Portal at Fenway Park. Hsi Wu the Sky Demon, flies out of the Demon Netherworld but it's right in front of the girls bathroom door, and his tail snaps of as Jade tries to close the door. Hsi Wu disguises himself as one of Jade's classmates and they become friends. But once Hsi Wu learns that Uncle put a Chi Spell on his tail, an angered Jade uses some of the Talismans to confront him.

Jackie discovers a necklace, known as the Eye of Aurora, that allows its user to teleport anywhere by saying "Return to (name of place)". To occupy Jade, he signs her up for Buttercup Scouts. However, an evil treasure hunter arrives looking for the necklace, which Jade has taken on a camping trip to Summit Hill with Jackie.