The Tiger Talisman splits the dark and light sides of Jackie in two, which makes it easy for Valmont to trick his dark side into working for the Dark Hand. The light Jackie could not do anything, he does not want to fight, while the dark Jackie steals the 12 talismans from Section 13. Both halves fight for the talisman, but Valmont gets to it first and uses it to turn Shendu into it's old self again, an alive, giant dragon demon.

Shendu alters the Book of Ages, and changes history. In a world where demons rule, Jade remembers how things were, and must convince her Uncles to help her set things right.

Jackie is poisoned by the Dark Hand and will give him the antidote for the talismans. Jade steals all the talismans, while the Dark Hand destroys the antidote. When Jackie fully turns to stone, the Horse Talisman heals him.

Jade uses the latest talisman to turn herself into a monkey to escape the Dark Hand, but the boat collapsed and the Dark Hand, Jade, and Jackie are stranded on an island. Jade gets caught off guard when another monkey takes the talisman, and now Jackie must find Jade, while the Dark Hand is trying to find the talisman.

Uncle helps Jackie retrieve the Pig Talisman from the Dark Hand's newest enforcer, Hak Foo, using the Dog Talisman's power of immortality. Jackie and Jade could not believe the strength that Uncle used on the Dark Hand.

Shendu retrieves all twelve talismans and transforms into a humanoid dragon. Now, he is on the loose and ready to destroy the entire continent of Asia. Jackie, Uncle, and Jade must find the demon and annihilate it before Asia is dismantled. Uncle makes a magic potion that allows Jackie to penetrate Shendu's skin to steal the twelve talismans back.

Jackie and Jade set out to find the Snake Talisman in a cave in South America. They cross paths with an egotistical "archaeologist" shooting for a TV show. After catching wind of their quest the "archaeologist" steals the Talisman. Things become more complicated after the Dark Hand shows up.

Tohru's mother comes to visit him and clashes with Uncle. Meanwhile, Tohru is almost seduced by a rival gang, the Black Hand to return to crime and help them steal the statue of the Golden Octopus.

The Dark Hand, with the power of the Talismans, goes on a crime spree. Although Jackie is eager to leave Section 13 behind, he agrees to help them one last time against the Dark Hand. Meanwhile, Shendu escapes back to the real world and tries to possess Jackie but accidentally possesses Valmont instead.

The Dark Hand goes hunting for the legendary Pan'ku Box which will lead them to the eight Demon Portals. Knowing that the Dark Hand is too strong with the Talismans for Jackie and Uncle to handle alone, Jade recruits El Toro Fuerte and Viper, along with the reformed Tohru, to form the J-Team.

Shendu and the Dark Hand find a clue to the first gate that will enable him to release his sister, the Mountain Demon. Jackie goes to Japan to stop them, while Uncle begins to train his new apprentice, Tohru. Meanwhile Jade causes havoc with a duplication spell.

While exploring some Pyramids in Mexico, Jackie gets a call from El Toro. He needs Jackie's help dealing with the legendary El Chupacabra.

The Dark Hand allows themselves to be captured and sentenced to prison so they can open the Wind Demon's portal in Hollowlands Prison. Jackie must go undercover.

Jackie guides a wealthy museum supporter on a expedition to find the remnants of the Muntabs. They discover the Muntabs aren't extinct.

Shendu goes to Hollywood to free his brother the Thunder Demon. Jade tries to make Jackie the next big action superstar in Hollywood as Jackie tries to prevent the demon from returning.

Jackie and company stop in ghost town. They find a book with the story of Jackie's ancestor who was a sheriff in the Old West.

When her classmates get a tattoo, Jade decides to get one also. The design she chooses, however, comes from a magical book, which has unexpected consequences.

Jackie is asked to authenticate some artwork in Paris. The art is stolen by Origami, a thief who can fold himself like paper. Jade calls Viper hoping the ex-thief can help them capture him.

The Dark Hand must travel into space to free Tso Lan, the Moon Demon. Jackie and Jade travel along as stowaways on their stolen shuttle and must hold off the demon so Tohru can arrive on the reserve shuttle with the Chi Spell ingredients. With Uncle handling the incantations from NASA Mission Control, they must seal the Demon Sorcerer back in the void before he uses his gravity-manipulating powers to change the face of Earth forever.

Jackie is excavating some ancient armor when Uncle reveals it is the Armor of the Gods. This ancient suit of armor was worn by the Eight Immortals in their battles against the Demon Sorcerers. It proves quite convenient when the Dark Hand travels to Spain to find the portal of Dai Gui, the Earth Demon. However, sealing Dai Gui is complicated, as Jade used a sleeping potion on Uncle because of his constant complaining.

Section 13 sends its best Agent, Taggart McStone to stop Dr. Necrosis. Jade stows away and accompanies him on his mission, sending Jackie after them.

The Dark Hand seeks out the next Demon Portal at Fenway Park. Hsi Wu the Sky Demon, flies out of the Demon Netherworld but it's right in front of the girls bathroom door, and his tail snaps of as Jade tries to close the door. Hsi Wu disguises himself as one of Jade's classmates and they become friends. But once Hsi Wu learns that Uncle put a Chi Spell on his tail, an angered Jade uses some of the Talismans to confront him.

Jackie and Uncle are supposed to explore an underground city the same night as Jade's theatrical debut. Jade's upset that no one will be there to see her perform, and comes up with a solution. An ancient evil is freed from the underground city seeking revenge on the descendants of the one who imprisoned it.

Jackie discovers a necklace, known as the Eye of Aurora, that allows its user to teleport anywhere by saying "Return to (name of place)". To occupy Jade, he signs her up for Buttercup Scouts. However, an evil treasure hunter arrives looking for the necklace, which Jade has taken on a camping trip to Summit Hill with Jackie.

Jade, Uncle, and Jackie escape from Shendu's palace with a few talismans taken from Shendu. Using Jade's memories of the Immortal symbols, they embark on a mission to find the other members of the J-Team and manage to banish half of the Demons in the process. Realizing what has transpired, Shendu and the other three remaining Demons make a final stand at Australia to prevent history from being corrected.