A young man who received letters from his birth mother longs to know the truth of the words she wrote, a man haunted by the memory of his younger brother being taken from their home seeks to reunite the family.

A Vietnam vet hopes Lisa can hep him make amends for the past by locating the daughter he lost custody of 40 years ago; and a woman's struggle to fit in takes a surprising turn when Chris reveals a series of stunning coincidences very close to home.

A Texas lawman seeks Lisa's help to tackle the investigation of his birth and adoption.

Chris tackles the mystery of why a woman was left in a box hours after being born near an Ohio gas station. A woman enlists Lisa's help to locate her biological mother; no one is prepared for what they discover, and changes the woman's life forever.

Musician Mark has been eager to find his biological mother since he learned she was an award-winning cellist. Unravelling the mystery, he uncovers heartbreaking details and life-affirming surprises and finally discovers the truth.

A man searches for his birth mother, whose disappearance when he was 5 years old has haunted him his entire life. A woman hoping to find any member of her biological family must face shocking realities about her true past.

Chris aids a woman's search for her father after she was shuffled through 28 foster homes; two radically different sisters, adopted into the same family, seek Lisa's help to search for their biological mother.

A woman whose parents kicked her out after learning she was pregnant tries to find the son she hasn't seen in nearly fifty years; a man desperate to find his biological brother tries to heal his mother's broken heart.

Two brothers navigate a painful past as they search for the family and love they’ve longed for their entire lives. Their journey reopens decades-old family mysteries surrounding their bith mother, twin siblings, and a baby who was only rumoured to exist.

Lisa helps a man yearning to discover his biological roots, but fearful of rejection from the family he has never met; and Chris reveals the truth to a woman who has felt guilty that her birth might have devastated the life of her 14-year-old mom.

A woman whose daughter perished in a car accident hopes to find comfort in locating her granddaughter, the baby her daughter placed for adoption 26 years ago. A woman yearning to meet her birth mother is stunned by an unlikely figure in the search.

A mother forced to give up her baby 31 years ago still holds onto his baby blanket and hopes to see him again; an adopted woman suspects mysterious circumstances surrounding her birth and wants to find answers.

A woman discovers her mom kept a life-long secret about the man who raised her & realizes her biological father doesn't know she exists. An adopted woman's only hope for finding her biological family is through DNA. Is she ready for what it uncovers?

A woman searches for her beloved sister who she tried to adopt herself years ago, but hasn't seen since she was five years old; a couple is desperate to find the son they placed for adoption fifty years ago when they were teens.

A woman searches for her brother, hoping to fulfill a promise she made to her late mother. What she discovers blows open a 40 year old secret about her parents' past. A woman consumed by a lifelong search for her mom finds hope with a new DNA connection.

A man seeking redemption from his troubled past longs to reunite with the grown son he only got to hold for a few minutes as a baby. 46 years after placing her daughter for adoption, a woman still carries the feeling of guilt for being an unwed mother.

Lisa meets a woman who was left on a curb by her mother when she was just four years old; Chris uncovers stunning information for a woman searching for her family that leads to an unexpected reunion.

A man who always longed for a sibling stumbles upon a shocking family murder; Lisa meets a woman eager to find her biological mother, but she also finds information that changes her view of the past.

Lisa tackles the mystery of why a woman was abandoned in a trash can as a baby. Unexpected DNA results throw a woman's entire identity into question - but no one is prepared for the shocking details Chris unearths about the day she was born.

Identical twins enlist Lisa's help to unlock the mystery of why they were placed for adoption. Chris hopes to fulfill a deceased father's wishes by tracking down the first-born son he and his wife had placed for adoption when they were young lovers.

Photo evidence suggests that an adoptee and mother may have been unknowingly connected for years; a woman discovers some shocking news about her biological family.

Susan aches for a mother-daughter relationship: She is searching for both her biological mother and the daughter she placed for adoption as a teen. Tammy is still haunted by never getting to say goodbye to the son she gave birth to over 30 years ago.

Lisa meets high school sweethearts desperate to reunite with the daughter they placed for adoption while they were teenagers. Chris unlocks the mystery behind a woman's birth, something her biological mother had hidden from the entire family.

A woman longs to meet her birth father, a man she credits for saving her life during a difficult childhood, even though they never met; a desperate man hopes Lisa can end a 57-year search for his infant sister, who he never stopped loving.

Long Lost Family sees a dramatic turn of events as Chris and Lisa investigate two seemingly different cases. A chance discovery raises the tantalizing prospect that the mother and son they're helping may be looking for one another.