On his deathbed, the notorious gangster Al Capone gave a tile to his most loyal servant. That tile, along with four others, would reveal the location of his greatest treasure. After a quick phone call from Fujiko, Lupin and company are on the case. Quickly, they acquire four of the necessary tiles; but soon after, Fujiko is captured by the evil mob boss, Lord Chinkai while Lupin is intensely interrogated by Stromo the mercenary.

With the permission of the ICPO Captain, Inspector Zenigata hatches a foolproof plan to at last capture Lupin. By melting down six tons of gold, forging it into the shape of a meteor, and then televising it's discovery to the world, Zenigata is positive Lupin will try to steal it. Indeed, Lupin does steal it; but under closer inspection with Goemon's sword, the meteor appears to be a gold-plated rock.

Lupin sneaks into an old castle to steal a collection of priceless angel paintings; what he finds instead is a teenage girl named Flora. Despite his numerous objections, Lupin cannot seem to get rid of her, and she accompanies him back to his hideout. As it turns out, Flora is the daughter of the late Malcolm Hurst, owner of the angel collection. If Lupin agrees to let her be a thief for the next three days, she will reveal the location of the paintings. Lupin has no choice but to put up with this energetic girl all while avoiding attacks from Hurst's greedy ex-wife, who wants the paintings for herself.

Deep beneath the whirlpools of the Bermuda Triangle, Lupin and Jigen discover a pirate ship containing tons of Spanish gold. Before the two can collect it, a submarine manned by a team of female pirates intervenes. After a quick skirmish, Lupin and Jigen escape empty-handed, as do the pirates who cannot get past the whirlpools to reach the gold. Later that evening, Fujiko is kidnapped right before Lupin's eyes. The Captain informs him that if he wants to see Fujiko again he must steal the gold for them. Will the pirates hold up their end of the bargain? And whose voice is Lupin hearing in his head?

Lupin, Jigen and Goemon head to an ancient South African temple to receive a treasure map from a retired Nazi. Shortly after receiving the map, it is stolen from them by two young soldiers and a giant condor who are working for another former Nazi. Fleeing with the map, one of the soldiers, a young lady, encounters Goemon. Before she can shoot, Goemon cuts all of her clothes to ribbons not realizing she was a woman. She escapes with the map via her pet condor while Goemon, disgraced by his actions, leaves to meditate. Will Lupin be able to outwit the former Nazi? And can Goemon ever get the image of naked women out of his head?

Alone, Jigen enters a bar to meet with his old war buddy, Giranko. Back in his army days, Giranko taught Jigen his infamous quickdraw. But his friend seems troubled. Soon, the enemy army invades the city, and Giranko heads off to battle with Jigen not far behind. Meanwhile, Lupin and Goemon search the city for their lost comrade so they can find the lost treasure they came in search for and leave. But Jigen will not go. What is Giranko hiding? And can Lupin withstand the might of an entire army?

Back in her younger days, Fujiko performed a heist with the man known as Death Garb. Greedily, she left him to die so she could have the money for herself. Now, Death Garb is back and has the ability to effortlessly dodge bullets. Lupin dedicates himself to Fujiko's survival, but Fujiko seems more interested in using him as a shield. After first avoiding a round from Jigen's magnum and then the best strikes Goemon can offer, all hope seems lost. How did Death Garb obtain his new power, and can Lupin devise a way to kill him?

Deep within the frozen Alaskan wilderness, a mysterious cult chants before a sold gold Virgin Mary idol. The high priest prophesizes the coming of the great demon who will steal their sacred artifact. Elsewhere, Lupin and Fujiko are escaping a fleet of police officers. Without warning, a team of hooded cult members appears and quickly abducts Fujiko right from their getaway car. Lupin gathers his teammates and heads off to Alaska to save Fujiko before she is burned at the stake. All is not as it seems, however. What is the true identity of the high priest and his cult? And does somebody else have eyes for the Virgin Mary statue?

Lupin visits a doctor to seek treatment for one of the worst cases of athlete's foot in the world. The Doctor takes a skin sample and informs him that the only way to make a cure is with powder from an ancient seed locked away in a museum. Unable to withstand the horrible itching, Lupin sets off immediately to steal the seed. Unfortunately for him, he was set up, and Zenigata arrests him with haste. To make matters worse, the Doctor has plans for the skin sample that he took from Lupin.

A message appears in the morning paper reading "Lupin Is an Idiot". Lupin says it is a secret code from his late grandfather telling him it's time to reclaim Lupin the First's prized diamond. But the gem is locked away in police headquarters, encased in a globe of liquid. Should a single vibration touch the liquid, the entire facility will explode. To make matters worse, Lupin is tricked into accepting a challenge from the police chief. If he does not steal the diamond within one week, he will spend the rest of his life in prison

In Chicago, a sniper kills a man under the orders of the mysterious "Mother". Even more strange, Fujiko seems to be under her spell. Lupin sneaks into Mother's mansion and manages to steal the Dracula Heart ruby. Once every century, this ruby bleeds, and whoever drinks its blood is granted youth for another 100 years. Mother has used the blood to maintain life for the past 300 years and will not be denied. She wants the ruby back, and Fujiko will do anything to reclaim it for her.

After much labor, Lupin successfully steals a painting of Lupin the First's beloved. He is less than thrilled to discover that it is in fact a fake. Fujiko enters the scene and explains that it is actually a Valtan forgery. Valtan has the artist and his daughter Sofia captive in his palace; he forces him at gunpoint to recreate his own paintings. Lupin heads off to Valtan's palace to rescue an old friend of his grandfather's and maybe keep a few paintings for himself.

After narrowly escaping Zenigata, Lupin is both physically and mentally exhausted. However, he jumps at the chance to help Fujiko. Together, they attend a party of rich women located in an old castle, intent on stealing all their jewelry. Things take a turn for the worse when the castle tower they are in turns out to be a rocket ship that carries them all to an island nation at war. Zenigata is then called in to collect funds for the ransom of all the women as well as capture Lupin. When he gets there, he finds Lupin hanging from a cross, seconds away from being shot to death by Fujiko. It is all part of the plot designed by the mysterious Madam Razor.

In Central Park, Zenigata waits outside an armored car to ambush Lupin. Not to protect the money, but because Lupin is the prime suspect in the kidnapping of Madam Fiona. Lupin steals the money, eludes Zenigata, and delivers it to another party. It would seem he had been hypnotized by Fujiko to perform the task and is quickly knocked out with a monkey wrench. Zenigata arrests Lupin; and shortly afterward, Madam Fiona is set free claiming Lupin to be her kidnapper. Fujiko arrives at Madam Fiona's mansion expecting her cut of the profits only to find that Madam Fiona insists that she marry her bratty son, Roger. With the help of Goemon and Jigen, Lupin escapes prison.

In an abandoned baseball stadium, Jigen and a mysterious woman are shooting it out. She soon bests Jigen and proceeds to take on Goemon in a sword fight. She manages to strike him down as well. Lupin shows up and congratulates her on the success of her training with him. The woman's name is Glory, and Lupin needs her in order to access an ancient treasure. Only a girl who is pure of heart can ride atop a camel that will lead them to the treasure. Lupin and Glory head off to Jordan leaving Jigen and Goemon behind. They find out quickly that Lupin is in danger. Bruce the Robot-Man, one of the world's greatest assassins, is after Lupin and his $100,000 reward. Will Glory's training save her when the Robot-Man strikes? And is she all that she seems to be?

Lupin and Jigen sneak aboard a yacht narrowly avoiding Zenigata; aboard that yacht is the precious golden apple being sent to New York for exhibition. Zenigata catches on to Lupin's plans to steal the apple and keeps his eyes open. Meanwhile, Fujiko is trying to get her hands on it as well, but she is stuck with the owner of the apple, the annoying Prince Oji. When the attempt on the yacht does not work out, Lupin has plans for the New York Marathon. Will Lupin or Fujiko ever get their hands on the apple? What tricks does Zenigata have up his sleeve? And what secret does the golden apple hold?

It is Fujiko's birthday, and this year she wants the "Golden Puppet" worth ten million dollars. If Lupin can get her the Golden Puppet, Fujiko claims she will marry him. Lupin goes to the bank vault and escapes with all the gold nuggets. Now, they must get married, but Fujiko gives Lupin a sleeping potion and escapes with the Golden Puppet. Lupin manages to find her, and they both get arrested by Zenigata. In jail, Lupin pleads for a wedding in the biggest church, and Zenigata allows it. Will they really get married? Where did Goemon and Jigen run off to?

Lupin and Jigen are after the party presents of "the boss of the underworld". While checking out the future scene of the crime, Lupin finds a dancer named Jenny. Jenny is being stalked by two thugs, but Lupin saves her. Lupin hangs out with this Jenny so he can get some valuable information on the premises. Will Lupin succeed in his mission, and what secrets does Jenny hold?

Lupin breaks into a prison and frees a strange looking man he knows from previous heists. When the strange man questions what Lupin plans on doing with him, Lupin begins to talk about a hidden "safe trunk" containing millions. Lupin proposes an offer to split it 50-50 if he helps him get the trunk, an offer the man readily agrees to. But Zenigata is on Lupin's tail. Who is this man, and will he really agree to help Lupin? Will Jigen and company come to help? Will Zenigata finally catch Lupin?

Lupin and Fujiko are enjoying a nice day together. Fujiko asks Lupin to steal an expensive painting. Learning Fujiko is the reward, Lupin jumps at the job. After Lupin runs off with the painting, he learns its a fake and finds himself in a bind when he learns Fujiko double crossed him and is working for the owner of the painting. After finding out the man once conned him years before, Lupin begins to wonder what this man plans to do. Lupin's suspicions get the best of him, and after a couple of failed attempts, he breaks into the man's house. What does this man wish to do, and what is Fujiko up to?

An ancient japanese piece of art is being excavated when Lupin and Jigen pop onto the scene. Apparently, the "Golden Legend" has a dazzling pearl where its eye is, and Lupin wants it. After learning more about the "Golden Legend", they kidnap one of the archeologists, and Lupin and company find themselves on a wild adventure with Zenigata on their tail... and maybe someone else too.

Lupin and company are sneaking inside a room with a vault in it. After breaking into the vault, they all begin to steal thousands of wonderful diamonds. But a fire breaks loose in the room, and they narrowly escape with only one diamond but without Fujiko. Lupin immediately investigates the incident and soon finds that the diamonds are all fakes and part of a plan to make the cost of the diamonds rise. What Lupin doesn't know is that the owner is telling Zenigata that Lupin burned the diamonds to increase their value. Lupin will not let this go unanswered. What will Lupin do? Where did Fujiko run off to?

Lupin and company plan to rob a bank, but not just any bank. This bank carries the "Prince of Oils" money and has extremely high security. Also, wheels on the bottom of the bank enable it to move, making it an unusually difficult task for Lupin. In order to get inside of the bank, they need to wait for the bank to stop moving. Disguising himself, Lupin manages to get into the bank, but will he be able to leave?

Lupin has his sights on a valuable antique owned by Hong Kong businessman Gozen. However, Gozen has plans to amuse himself by using the antique to bait Lupin and the gang into a trap. To counter Goemon's swordsmanship, Gozen enlists the kung-fu expert and Goemon's former rival Seiryu. Silver threads gleam in the moonlight, and the martial arts battle rages in the sky between the skyscrapers. Can Goemon best his rival and help Lupin secure Gozen's prize?

Lupin has set his eyes on the "Heart's Eggs", but the woman who possesses them has them locked behind an impregnable safe. Can Lupin penetrate the safe and steal the eggs? Are his motives selfish, or does he have a benevolent streak?