Just as Jim Phelps and the others unwittingly become caught up in a royal power struggle, a bomb goes off, seriously injuring Paris and revealing his disguise.

Publisher Granger is controlled by the Syndicate, killing reporters and protecting Syndicate-owned politicians in his state. The IMF must make sure the voters know what Granger is up to before the next elections. Appealing to Granger's interest in UFOs and his obsession with immortality, chauffeur Barney hits him with a paralysis drug delivered by bee sting and Jim and Casey mysteriously appear in a light show, ""cure"" him with futuristic equipment, and appear. Thanks to IMF-rigged reports of UFOs, Granger believes they are aliens! After another rigged death of Casey that Jim ""cures,"" Granger begs for immortality. Jim agrees if he publicly renounces his way. Granger exposes the Syndicate candidates and then is shot by his former aide and Syndicate man.

An $8 million army payroll has been stolen from a base in SE Asia by the Stafford family, Syndicate drug smugglers. The IMF must recover the money. Jim and Barney steal a Stafford truck and then offer to sell it back to the family if they pay ""protection."" Jim meets with brother Doug to convince him brother Art has ordered a hit on Doug - however, Art has put a hit on Jim and he is ambushed and gets amnesia. Meanwhile, lounge-singer Casey meets with Doug and sets it up so he thinks Art is trying to kill him. Doug makes a deal with Barney for protection from his brother in return for $2 million and leads the IMF to the money - they arrest everyone and convince Art to tell them about his plan to kill Jim. Meanwhile Art's killers are on Jim's trail and when Barney gets hold of him, he manages to recover his memory just in time to thwart them.

In order to stop an invasion and shatter an alliance between two countries, the IMF team must photograph and break a code in a matter of minutes.

The team tries to get a deposed dictator to divulge his Swiss bank account number by tricking him into believing World War III is about to begin.

Jim and a female agent pose as scientists who have invented a new drug in order to replace a real drug that turns people into willing slaves.

An imprisoned priest is about to be executed, so Jim and Willie pose as U.S. religious workers who are willing to trade guns in exchange for his safety.

As Barney Collier attempts to break into a safe that contains an incriminating file, Paris convinces a mob figure that he can read the mind of his double-crossing boss.

The IMF team has to try and gain access to a nuclear reactor complex, where a terminally ill officer plans to detonate an atomic bomb.

Jim Phelps poses as an amnesia victim in order to retrieve a stolen isotope, one that could make nuclear weapons affordable to any country.

Paris masquerades as Zastro, a magician who has come to entertain during an arranged wedding between the king's sister and a ruthless usurper.

An undercover agent, Hays, assigned to gather evidence against Syndicate head John Lawton, is blinded in an explosion. Lawton's lieutenant Deetrich and his business advisor Matula are rivals - Matula is actually an IMF undercover plant - so the IMF must keep him from being exposed and make sure he takes Lawton's place. Lawton believes Hays is working with someone in his organization. Jim, surgically blinded, takes Hays' place. Lawton has his henchman Brown watch Jim and then offer him money to reveal the leak. Deetrich pays Jim to fingeer Matula but in the final showdown Matula plays Lawton an IMF-supplied tape of Deetrich and Jim planning to implicate him. Deetrich and Brown are killed in the subsequent shootout and Lawton and Matula leave, telling Barney (infiltrated in as a mobster) to take care of Jim.

Two underworld leaders, Hatcher and Thorne, have called a conference of Syndicate leaders to form a massive holding/laundering company. The IMF must obtain their joint Swiss bank account number. Jim gets in as a mobster and sabotages the tram that is the only way to the meeting. Willy slips in as a repairman and Casey lures down Thorne, whom they capture and then offer to return to Hatcher in exchange for the exact amount the mob leaders invested. He gets scammed into losing the money and Barney replaces the money in the safe with counterfeits. The IMF makes it look to Thorne like Hatcher kidnapped him then let him escape. When it is revealed the money is counterfeit Jim ""rescues"" him from being killed by the mobsters, then give Hatcher (with a weak heart) a fake heart attack as they escape down the tram. Hatcher gives Jim the bank account number and the team slips out of the tram with the $4 million while the weakened Hatcher remains behind - when he gets to the bottom he and Thorne k

Syndicate boss Frank Brady and his underling Martin Stoner are terrorizing Southwestern businessman, forcing them to partner with the Syndicate. The weakspot is Stoner's wife Lois, who has become an alcoholic under the pressures of her husband's work. The IMF capture her and dry her out while Casey takes her place. She goes on a retreat and Brady sends a killer, Dekker, to keep an eye on her and kill her if she talks. Willy infiltrates Brady's organization and finds out some information which he leaks to Casey, who reveals it in an encounter group session and Dekker seriously wounds her. Casey continues with the mission while Brady suspects that Stoner leaked the info to his wife. Willy sets up Brady's goons to be arrested and claims they were set up - Brady sends him to kill both Stoners. Willy fails and Stoner heads for the bank with ""Lois"" to get his Brady's records. Unfortunately the real Lois escapes and tips off Brady. Brady and Dekker go to the bank, and Dekker kills Martin Ston

Berlinger, a millionaire manufacturer and stolen gem dealer, will be transferring diamond to a Syndicate boss for $75 million. Only one man knows where the diamonds are - Hoffman, Berlinger's former lieutenant, who stole them. Berlinger is torturing Hoffman for their location. The IMF must get the gems and the money. Barney springs Hoffman and they become partners so Hoffman dives for the gems (hidden on the body of a courier sunk at sea). Casey brings Berlinger to Jim, posing as a diver, who offers to get the diamonds. Willy follows Hoffman to the gems and the team knocks him out and takes him into custody - then Jim leads Berlinger to the same spot and offers to make a deal in return for his $5 million payment. Under pressure from the Syndicate, Berlinger agrees and in the subsequent meeting the police capture everyone.

Wendell Hayes, the brother of an imprisoned Syndicate enforcer, has stolen a canister of nerve gas and threatens to use it if his brother Cayman isn't freed - the IMF must stop him and recover the gas. Worse, the canister has a defective casing that Wendell is unaware of, and will release the gas in 43 hours anyway. And...Cayman dies of a heart attack in jail, forcing the IMF to have guest-agent Bill Williams take his place. The IMF has Hayes' imprisoned girlfriend Saretta ""escape"" with prisoner-Casey handcuffed to her. Saretta takes Casey to a winery in a IMF car with a bug on it that Barney traces. Jim delivers ""Cayman"" but Hayes doesn't turn over the gas. They track Hayes to an observatory but he gets word via his partner Tully that his brother tied and he unmasks Williams-as-Cayman. Hayes and Tully shoot it out over an argument and with his dying breath Hayes tries to shoot open the canister...hid in the observatory roof, revealing its location to the IMF.

Syndicate boss Chandler's alibi is provided by Lt. Governor Harrison, who is in Chandler's pocket. Chandler has the husband of the only witness, Nora Dawson, get her committed and proceeds to have her driven insane at a mental hospital he controls. The IMF must get her out and have her testify in 24 hours. Jim gets Casey committed and she is put in a room near Nora, then he manages to get to Nora's cell and she and Casey switch - Jim then takes Nora-as-Casey out. The team get Nora off the island - when Casey-as-Nora is called to testify, she babbles insanely but then removes her mask while the team bring the real Nora in to testify.

Shanks and Blake are Syndicate men who run the loan shark racket in the Islands and are preparing to transfer $10 million to the mainland, leading to the Syndicate expanding their operations there. The IMF must stop the Syndicate's expansion. In Hawaii the IMF's in-and-out operation goes bad when Willy is captured and turned over to Dr. Matier, who injects him with a near-lethal truth serum. To get Willy out and finish the mission, Casey approaches Shanks and drugs him into helping the IMF steal the $10 million, while Jim approaches Blake and claims to be a Syndicate man from the mainland. The IMF make Shanks ""disappear,"" presumed dead, to convince Blake his partner sold him out. Then Casey wakes up Shanks and Jim and Blake confront him - Casey's fake ""confession"" seals the deal but then Syndicate man Barney fake-shoots Jim and Casey just as Syndicate man Bolt arrives. Confused, Bolt takes them all to Willy hoping his information will straighten things out. Willy manages to escape wit

Syndicate boss Orin Kerr runs the casinos and the IMF needs to get the evidence against him to put before the state legislature. Kerr's boss distrust him because of his extravagant lifestyle and Syndicate man Cameron plants a bug in Kerr's office, which the IMF taps into. The IMF then set Kerr up with fake conversations that make him look bad to his bosses - Cameron hears Casey and Kerr discussing a heist of the vault, and Jim shows up with a background indicating he pulled off a similar heist 12 years ago. Barney manages to steal the money out of the impregnable vault while Kerr thinks he can get the missing money from Jim's earlier bank heist by putting him into debt at the casino. Kerr follows Jim to the hidden money which is actually his own) and grabs it, and then Cameron shows up and demands to know why Kerr has carrying current currency. Dumbfounded, Barney intervenes and Kerr flees into the arms of the police, where he is forced to testify against the Syndicate in return for pr

The wife of a deceased scientist, Kurt Zubrovnik, is being pressured by Eastern forces to work for them. They are using a phony psychic to convince the wife her dead husband wants to defect! Accompanied by IMF ""psychic consultant"" Ariana Domi, Rollin and Barney try to disrupt the fraud and convince her to return to working for the U.S. The psychic, Poljac, is torturing the husband for information to use to convince his wife Poljac's powers are real. Ariana senses a real ghost present. In the end, Rollin sets up a final seance and Barney prepares to use a technological projection of Zubrovnik to decry Poljac. However, a blackout causes his equipment to fail, and Ariana's alleged powers, plus some ghostly phenomena, allow them to complete their mission.

Double-agent Elena Del Barra is acting bizarrely, sending a microfilm of defense secrets from her own country. Rollin is sent into investigate, and return the microfilm without its theft ever being detected. Complicating matters is that an assassin, Callao, has been sent to kill her if Rollin can't figure things out in two days. Rollin convinces her to meet with teammate Dr. Enero, who hypnotizes her and learns she is suffering from a post-hypnotic suggestion to denounce the President, her good friend. With time running out, Rollin must return the microfilm, figure out the traitor, and save Elena.

As Barney taints the water system with a mind-numbing drug, Jim is captured and put on trial, where he must discredit an enemy scientist.

Paris poses as a counterfeiter in order to gain access to a safe and destroy millions in phony money, as well as the plates used to make it.

Upon his release, a prisoner plans to fund neo-Nazis with stolen money. So a submarine voyage is simulated in order to transport him to his contact.

A country is unaware that its premier is dead and that a double is about to appoint a successor. So Barney Collier concocts a mechanical man to take his place.