At Rino and Pinuccia’s wedding, Elena accepts Lila’s invitation to go on holiday, provided the destination is Ischia, where she knows she’ll find Nino. On the island, Elena, Lila and Pinuccia begin to spend more and more time with Nino and his friend Bruno and Lila starts to take a strong interest in Elena’s summer reads. As Lila and Pinuccia exhibit signs of nervousness when their respective husbands come to visit for the weekend, Elena is thrown when Lila comes to her bedroom to make a confession.

Elena's relationship is threatened when Antonio discovers she has asked the Solaras' help to keep him from doing military service, while Lila remains rebellious in her marriage to the often-violent Stefano. After a photo of her is exhibited at a wedding dress shop in the center of town and becomes the subject of much gossip, Lila makes a bet with Elena about how the whole affair will end.

With Lila on her honeymoon on the Amalfi Coast, Elena struggles to handle school and her relationship with Antonio. When Lila returns with visible bruises on her body, the two girls revert to their natural closeness and Lila’s will to take revenge against her husband grows. Elena continues to be bewitched by Nino Sarratore’s charisma but chooses not to mention him to Lila.

Upset that her picture is featured prominently in the new shoe shop Stefano is opening with the Solaras, Lila comes up with a creative solution to deal with the matter and enlists Elena’s help. Though Lila begins working at the Caraccis’ new grocery store, she continues to resent her husband’s business activities and the source of their income. Model student Elena invites Lila to a party at her teacher Ms. Galiani’s house; there, the two girls become acutely aware of the fact that they belong to ever more distant worlds.

A nervous Elena introduces Pietro to her family, and, though he instantly charms his future in-laws, Immacolata rejects their plans for a civil wedding ceremony. Months later, Lila falls ill due to the deplorable conditions at the Soccavo factory and makes Elena promise to take care of her son Gennaro if anything happens to her.

After Nino's unexpected appearance at her book presentation in Milan, Elena realizes her childhood crush never really abandoned her, and doubts begin to form about her fiance Pietro. Later, a scathing review leaves Elena questioning herself as a writer.

Concerned about Lila's worsening health, Elena seeks advice from her future mother-in-law Adele, who encourages her to write an expose on the Soccavo plant and the mounting unrest between rival unions. After several doctors' visits, Lila becomes determined to move back to the neighborhood despite being viewed as a pariah.

After a tense argument about plans for a family, Elena and Pietro marry in town hall, and later, are surprised with a reception organized by Adele. Though she had hoped to concentrate on her next book, Elena gives birth to a daughter and struggles to find time to write.

Following news of a murder in Naples, Pasquale and Nadia turn up unannounced at Elena's house in Florence, further fuelling discord with her husband. Meanwhile, Elena suspects all is not right with Lila when she's asked to take Gennaro on their summer beach trip.

On holiday, Elena grows increasingly exasperated with Gennaro and after receiving shocking news about her sister Elisa, she cuts the family trip short to travel back to Naples. Later, tensions mount at a dinner with the Solaras, and Pietro shares his unvarnished opinion of Lila with Elena.

Elena's marriage is more and more in crisis, Pietro is distant and she feels treated like a servant. One day, Nino Sarratore shows up at the Airota's door. He and Pietro become friends and say goodbye with the promise to meet again. Elena anxiously awaits their next meeting and finally resumes writing.

As Pinuccia returns to Naples, a new secret excites Lila and numbs Elena, who nonetheless becomes embroiled in its coverup. Subdued by Lila's charisma and indifferent to Bruno's flattery, Elena finds herself the keeper of a far darker clandestine series of events involving Donato Sarratore. After the girls encounter Michele and Gigliola, who have come to Ischia on a day trip, Lila seizes the opportunity to throw the whole truth in Stefano's face.

Following her formative summer on Ischia, Elena throws herself into her studies and looks towards a future outside of the neighborhood. After a brilliant finals performance, Elena happens upon Lila, who is working at the shoe store and has grand plans for a fresh start. As Elena leaves Naples to commence her prestigious university studies in Pisa, Lila decides to leave Stefano and moves into a modest apartment, but the failings of her plan soon emerge.

Three years into her time in Pisa, Elena has developed into an elegant and cultured young woman – but still feels like an outsider. After a consequential breakup, Elena falls ill and is visited by her mother, who has come to nurse her back to health. During the night, Elena takes to reading Lila’s diaries, which were entrusted to her for safekeeping; in these tomes, Elena discovers Lila’s dedication to her new role in the face of Stefano’s increasingly violent behavior.

With graduation in sight, Elena is overwhelmed by memories of her past and copes by drafting her first novel. Meanwhile, she finds a new suitor in Pietro Airota, the son of an esteemed academic. After Pietro proposes, Elena entrusts him with her manuscript before heading back to Naples, where she reunites with her family and visits Ada, who updates her on the tempestuous events she's missed. Upon receiving some unexpected good news, she sets out to find Lila, whose circumstances have seen a dramatic change.

Elena and Pietro meet Nino's family. Nino gives Elena his feedback on the manuscript, when he discovers that Pietro has not read it he shows hostility towards her, but in a veiled and underhanded way. Pietro's reaction to Nino's passive-aggressive attacks only confirms Elena's doubts about her husband.

Unable to forgive Nino’s betrayal, Elena takes Dede and Elsa to stay in Milan with Mariarosa and Franco. Following a tragic event, Elena gives in and moves into Nino’s place in Via Petrarca.

After Elena’s daughter Imma is born, Lila brings Elena’s mother to see the baby, but the visit is unexpectedly cut short when Immacolata collapses. When Nino and Lila take Immacolata to the hospital, Elena finds herself plagued with jealousy. Later, Marcello causes a scene when he insists Immacolata be moved to a clinic.

After Elena discovers that Carmen has been pressured into suing her for slander, she and Lila decide to work together on an exposé of the Solaras’ affairs. Later, Elena learns that their article may not be enough to put the brothers behind bars.

Elena considers moving back to Naples after being chastised by both Immacolata and Adele. Lila shares shocking news about Nino.

Still reeling from her breakup, Elena reconnects with Antonio, who shares the full extent of Nino’s betrayals. Later, Elena discovers that her newest book is a success, and tensions run high at Elisa and Marcello’s wedding, as Elena learns the Solaras are ready to wage war against her for smearing their family name.

On a visit to the neighborhood for the first time in years, Elena attempts to make peace with Immacolata and learns that her mother has been unwell. Later, when Elena and Nino return from a trip to New York, she and Lila grow closer after revealing that they’re both pregnant.

Elena and Lila spend the day together in the neighborhood, where Elena sees how well-respected Lila has become...as well as the peril brought on by Marcello’s drug running operation. Later, Lila and Elena desperately try to reunite with their families after a sudden earthquake forces residents to flee the city.

The disappearance of her old friend, Lila Cerrullo, causes 60-year-old author Elena Greco to reflect on the early days of their friendship in 1950s Naples, when Elena and Lila are two very different girls at the top of their class. When the girls discover the lair of Don Achille, a criminal figure who controls the neighborhood, they decide to confront him.

Elena grows tired of Gino, while Lila rejects two potential suitors at a cost. A rare outing into the city turns violent. Elena worries about not being there for Lila after accepting an invitation to spend the summer away from the neighborhood and her family.