After three happy years in foster care, Oakley Carlson must be returned to her biological parents. Her broken-hearted foster family accepts the decision until the mom receives a call on Oakley's 5th birthday asking if she can take the girl "once she's found." Oakley's birth parents claim they haven't seen her in a week, but the last verified sighting was 10 months earlier.

As the search for Lina stalls, a witness comes forward to shed light on the little girl's last moments on the playground, resulting in a startling new lead.

Enrolled at University of Montana, Ashley is on her way to a life unavailable to most women on the Blackfeet Indian Reservation. So many have gone missing or murdered in a community rife with drugs, alcohol and crushing poverty. When Ashley vanishes, a local reporter battles to get police involved. There are local suspects-an older man, a jealous rival, and the human traffickers who prey on indigenous women.25

Caleb Diehl's disappearance triggers an investigation that brings in local police, the DA and the FBI. The Diehl family is stunned by revelations that a close friend, who is a prominent local banker, has been implicated in financial fraud and is rumored to have unsavory predilections for the teenage boys he employs on his ranch. One of them was Caleb Diehl who has vanished without a trace.

Jon Riley loves sailing, rock climbing and the great outdoors. But when he goes missing and a human foot washes up in a nearby lake, his family fears the worst. Only, it's not Jon's. A serial killer is on the prowl and police contact Jon's family about a scar on his shoulder. But none of the remains are Jon. So where is he?

Echo Lloyd moves to a remote part of the Ozarks to be alone. When she vanishes, suspicion falls on her odd neighbor - and on her own daughter.

With no sign of Dylan, wild theories abound. Then attention begins to focus on the strange old man squatting in a shed a few miles from Dylan's farm.

Popular, diligent, adventurous, that was high school senior 18-year old Caleb Diehl according to friends and family. So when he doesn't show up at school, it's cause for concern. Could he have crashed his truck? Did he travel out of state to work for a girlfriend's relative? Or did a prominent local businessman who employed Caleb to work on his farm know more than he was letting on.

Chelsea Cobo leaves a psych hospital in Westchester, New York, and calls her mom to say she's grabbing food before coming home. Her mother never hears from her again. Did Chelsea simply run away, or is there something more sinister involved?

Two sex workers in London vanish seven years apart. Years later, police make an unusual announcement, raising more questions than answers.

Transgender indigenous woman Aubrey Dameron vanishes in the middle of the night. Shocking theories emerge as her aunt and uncle search for answers.

After surviving a suicide bombing overseas, Lina vanishes from a Texas playground. Was Lina's disappearance a mere wandering or a sinister abduction?

She thought she'd found the right man, a good step-father to her children. But her girlfriend says that before she and a teenage son vanished into thin air, Susan made a startling discovery about her second husband. Did it cost her life? Police say he replaced the floors, burned their mattress, and the house smelled of bleach. What they can't find-are bodies.

Police think Chase Hurdle jumped from a Bismarck bridge, but his family isn't buying it. The description of the jumper doesn't sound like Chase. A car found abandoned in a local park raises more questions and theories. The car was Daniel Olson's, a decorated veteran from West Fargo

22-year old Mackenzie Trottier walks out of her parents' home on December 21, telling her mom she will be back later. When she doesn't return that night, her parents aren't too concerned- Mackenzie has been known to be out of touch for a couple of days

When 14-year-old Max DeVries vanishes on a jet ski ride with a fellow vacationer in Aruba, authorities label it an accident. But is the truth much darker?

Heather Teague is abducted at gunpoint while sunbathing on a beach by the Ohio River. Investigators have compelling leads about who took her. Clues like bikini bottoms found in the woods and a mysterious Red Bronco spark theories. She could be alive, kidnapped by a crime syndicate and sold into sexual slavery. Or was she another victim of an alleged serial killer who focused on young brunette women? For 26 years, her devoted mother has been waiting for answers.

Cortney Lake is a single mom trying to get her life on track, even successfully fighting to enter a beauty pageant that doesn't let mothers compete. But when Cortney's mother returns from a barbecue to find her daughter missing, the mom knows that something is wrong. As thousands follow the case on social media, police obtain a video from a city bus that points to a troubled relationship and an ex-boyfriend who won't let go.

The investigation surrounding the disappearance of 5-year-old Tamra Keepness has devastating consequences for her family as Social Services takes custody of her brothers and sisters, a reminder of Canada's dark history of separating Indigenous children from their parents

Twenty-year-old Ryan Shtuka leaves home to work at a ski resort, hoping the experience will help him find a path for his future. That can't happen now. Ryan goes to a house party during a fierce winter storm and is never seen again. There are many theories as to what happened

After 15-year-old Kristen Galvan disappears, Houston police pick her up and say she may have been trafficked. She's recovering when she vanishes again.

19-year old Dylan Rounds goes missing without a trace from his farm in remote northwest Utah. Then Dylan's gun reappears mysteriously in his camper.

In search of her daughter Kristen, Robyn sets out on a journey into Houston's underworld, encountering pimps, johns, and con artists along the way.

Irene Gakwa comes to America from Kenya to join her brothers and become a nurse. When she disappears, her American dream becomes her family's nightmare.

When best friends Maisy Odjick and Shannon Alexander go missing after a high school dance in Maniwaki, Quebec, the police dismiss the Indigenous teens as runaways. With little police support, Maisy's family picks up the search with the help of the Kitigan Zibi Anishinabeg community