A dramatic car chase, a series of frantic phone calls, and two friends missing in the woods on an Oklahoma summer night. Once they're gone, rumors swirl.

12-year-old Jaliek Rainwalker goes missing in upstate New York. His parents say he ran away, but law enforcement suspect his father may be involved.

When Dane Elkins goes missing, it looks like he's gone off the grid. A 911 call points to a car crash. Or is his disappearance linked to mental distress?

When 14-year-old Justin Rutter doesn't come home one night, his family panics. Police think he's a runaway, but evidence suggests something more sinister.

Susan Walsh is a devoted mother working on a career in journalism but supporting herself as an exotic dancer. So when she disappears, there is no shortage of suspects. She has published an article exposing a cult of wannabe vampires living in Manhattan.

Single Bronx mom Kassandra Ramirez had just graduated culinary school and started her dream job as a chef. But after she told a relative I think I'm in danger, she vanishes. Her family begins a frantic search to bring her home - putting up fliers, checking trains, and searching under bridges.

Doted on by his sisters, Michael Samdass was the beloved son of a hardworking immigrant family. But he seems to undergo a personality transformation and one day simply vanishes. Could a mental health crisis be to blame? Or a bout of amnesia from a blow to the head? Investigators learn he was briefly arrested after a fight.

When Tamra Keepness, a 5-year-old Indigenous girl, goes missing from her home in Regina, Canada, the city comes together to find "everyone's baby." First Nations elders and police cooperate in the search for Tamra, exploring the hundreds of tips that flood in

For 25 years, friends and family have speculated about what happened to Susan Walsh, an ambitious young mother building a career in journalism who worked as an exotic dancer at night. Part 2 of this compelling tale, takes a closer look at the rogue's gallery of suspects

The sudden disappearance of Ali Gilmore sparks the biggest missing person investigation in Tallahassee history. A college graduate who holds down two jobs, she has been a role model for her younger sister. But investigators uncover a troubled marriage, a sketchy boyfriend and an unplanned pregnancy.

Granger Taylor is a mechanical genius who built a car from scratch when he was 12 years old. As a young adult, he has haunting dreams where aliens take him on an interstellar journey. After a few weeks of these vivid dreams, Granger leaves a note for his parents

After an angry fight with her boyfriend, Kelley Brannon paces a motel parking lot, refusing to return to the room. Waking alone at dawn, her boyfriend listens to a voicemail, her last trace, as she signs off "I am getting in a car." Whose car and where she went have haunted him ever since. But her friends and family are not so sure he's innocent. Was it him or was she abducted? Or did she ghost him and run away to reinvent her life?

When best friends Maisy Odjick and Shannon Alexander go missing after a high school dance in Maniwaki, Quebec, the police dismiss the Indigenous teens as runaways. With little police support, Maisy's family picks up the search with the help of the Kitigan Zibi Anishinabeg community

Chase Hurdle is a straight A student who loves singing, dancing, and his Catholic faith. He's looking forward to graduating from his North Dakota high school and studying psychology in college. His parents are baffled when he walks out of school one morning and goes missing

Investigators retrace Kelley Brannon's last days. The questions they must answer: Was she abducted by a stranger in the night? Did she befriend someone at the local bar who harbored bad intentions? Or did her boyfriend, with whom she had a stormy relationship, play a role in her disappearance?

Jason Landry leaves his university apartment and heads home for a brief visit. His mom, Lisa is woken up by a state trooper at the scene of Jason's abandoned car on a gravel road in the middle of rural Texas. His wallet, keys, and clothes are all discovered nearby. Captain Jeff Ferry believes the harsh elements and dangerous wildlife may have led to Jason's demise, but retired FBI agent Abel Pena believes something more sinister occurred.

Wisconsin grandmother Sandy Eckert disappears in the middle of the night. Does her husband know more than he's letting on?

A haunting social media post seems to predict an Indigenous mother's disappearance.

21-year old Matthew Weaver Jr.'s abandoned car is found on a remote road in the Santa Monica mountains. But where is Matthew? The police think suicide, but Matthew's sister and step-mom smell foul play and hire private investigators. Everyone has a theory. Was Matthew embroiled in a gang dispute? Was it a romantic entanglement? Or did he get too close to something he wasn't supposed to see?

Heather Teague is abducted at gunpoint while sunbathing on a beach by the Ohio River. Investigators have compelling leads about who took her. Clues like bikini bottoms found in the woods and a mysterious Red Bronco spark theories. She could be alive, kidnapped by a crime syndicate and sold into sexual slavery. Or was she another victim of an alleged serial killer who focused on young brunette women? For 26 years, her devoted mother has been waiting for answers.

Cortney Lake is a single mom trying to get her life on track, even successfully fighting to enter a beauty pageant that doesn't let mothers compete. But when Cortney's mother returns from a barbecue to find her daughter missing, the mom knows that something is wrong. As thousands follow the case on social media, police obtain a video from a city bus that points to a troubled relationship and an ex-boyfriend who won't let go.

The investigation surrounding the disappearance of 5-year-old Tamra Keepness has devastating consequences for her family as Social Services takes custody of her brothers and sisters, a reminder of Canada's dark history of separating Indigenous children from their parents

Twenty-year-old Ryan Shtuka leaves home to work at a ski resort, hoping the experience will help him find a path for his future. That can't happen now. Ryan goes to a house party during a fierce winter storm and is never seen again. There are many theories as to what happened

In search of her daughter Kristen, Robyn sets out on a journey into Houston's underworld, encountering pimps, johns, and con artists along the way.

Irene Gakwa comes to America from Kenya to join her brothers and become a nurse. When she disappears, her American dream becomes her family's nightmare.