A high-ranking member of the Klu Klux Klan check into the hospital with a medical condition, then collapses in the hallway, leaving Annie to perform mouth-to-mouth resuscitation on him. Another patient is a sexist construction worker who sat on a nail gun – so the female staff finds a way to get even with his snide remarks. Greg is smitten with a lady patient he's seeing… until her husband shows up.

Chaos breaks out in the hospital during a hurricane – the kitchen's flooded, the phones are out, and the roads are closed. So when Rose Nyland shows up to help, she's immediately stuck with Julie and the duo are assigned to gathering food from the patients – food that they later give to Laverne for the pediatrics ward. When the news arrives that the roof collapses in a burning building, Annie fears that her husband, a fireman, may have been killed. Sandy runs into a man with a broken leg, whom she dumped. Hank and Gina get trapped in an elevator and share a romantic moment. Two rival gangs start a knife-fight in front of the nurses' station (and threaten Rose) so it's Paco to the rescue.

Julie's first lover, Peter, checks into 3 West, and the two immediately start catching up on old times, with Peter revealing all the women he's slept with. But when Dr. Risken arrives to break the news that Peter's indiscriminate bed-hopping has left him a brief time to live with AIDS, he's enraged and Julie's freaked out. Julie, deathly afraid of catching AIDS, first avoids him but later lets him know that he won't have be alone when he dies. Meanwhile, Annie's mother-in-law moves in with her.

The entire staff is pulled in to cover a double-shift during the full moon. Julie tells her co-workers about her grandmother's theory on the full moon – how it's a chance to make up for missed love opportunities. Sandy finds herself falling for Charlie Deitz. Paco decides that he's going to ask out Gina. Hank wants to ask out a slut… but he changes his tune when Gina attacks him and sticks her tongue down his throat in the elevator. A hernia-surgery patient makes repeated attempts at escaping; a former astronaut arrives with a bump on the head; and Blanche Devereaux tracks down Dr. Riskin because she can't get a man to bed her.

Casey quits to take a new job, only to realize that her new boss hired her only for her looks.

The hospital is sold to the Healthweb Corporation, and the new owner, Mr. Waites, pulls one of his hotel managers to be the new corporate representative of the hospital. The new rep, Casey MacAfee (Loni Anderson), disguises herself as a patient for ""research"" and proceeds to annoy the staff. When Mr. Waites arrives, he gives Casey a promotion for her good work – he puts her in charge of the hospital as the administrator. Meanwhile, Gina finally announces her pregnancy (though at 5 months, it's more than obvious), and Hank finally proposes. And Jack begins his obsession with Casey, who begins her obsession with Harry Weston…

A student nurses decides she wants to emulate Casey; a hypochondriac can't accept turning 40; a man has a throat operation because he sounds like Jack Nicholson; Jack and Paco fight; Julie loses a patient.

The staff take turns talking to an accident victim in hopes he will come out of his coma.

Sandy must decide if she wants to move to Minnesota with her new boyfried; a patient confuses her medicine because she can't read; and Greg overacts in a training video.

Annie nearly died in a car accident, so she decides if anything ever happens to her and Fred, she's leaving the kids to Sandy. Sandy is initially taken with the idea… until Annie starts criticizing her habits and lifestyle. Meanwhile, Julie falls for a doctor who turns out to be an escaped mental patient. Greg announces that he has the ability to shapeshift.

Wanting to fit in with her new co-workers, Casey invites the staff to a Halloween party in her home, where she shows off her snow-globe collection. Julie, who has issues confronting Casey, steals one of the snowballs... and Jack gets blamed. Hank gives Paco a box of his ""guy stuff"" Gina was throwing away, that includes a very valuable baseball card.

Hank's brother visits and falls in love with Gina; Julie makes friends with a selfish patient; and a hospital administrator tries to prove Dr. Riskin isn't billing poor patients for their tests.

A mentally unstable patient (Larry Linville) is told that he has to cut sulfites out of his diet, so he responds by taking the staff hostage at gunpoint... Which doesn't sit well with Sandy, who was supposed to be off on a big date.

Hank gets testy with everyone when he discovers a lump in his scrotum... and then accidentally announces his news over the P.A. Dr. Riskin takes Julie's advice and stands up to the medical director, who then quits leaving her to fill his position.

When a patient comes out of a 38-year coma, Dr. Riskin shocks the staff by telling them she was once engaged to the man, and that they had a son.

Casey orders new, obnoxiously-loud, yellow hospital gowns, much to Annie's chagrin. Patients begin complaining that the new gowns are making them itch, so Paco and Jack are assigned to wash them. But after Paco puts the gowns in the dryer, it's discovered that they're flammable. When Mr. Waites shows that he's not happy with the flaming gown situation, Casey lets Jack take the blame. Meanwhile Hank tries to find a romantic way to re-propose to Gina, and he settles on a barbershop quartet... but Gina's taken a leave of absence and disappeared. And Julie points out to Annie, that she would rather ""swing"" like a gate than confront Casey.

Casey spies on the staff by installing a security camera in front of the nurse's station, and everyone begins ""performing for the spycamera."" Annie keeps trying to express her discomfort with the camera, but Casey keeps giving her the brush-off – so Annie jerks it off the wall. Meanwhile, Hank tries to locate Gina, but Julie's the only one who knows that she's returned to her native homeland. Jack passes himself off as a doctor to get into the doctors' lounge – but he ends up in surgery.

Casey tells everyone that they got fabulous gifts for Christmas, so they go out of their way to get her something nice. But when the box arrives, she finds that it's filled with padded hangers. Meanwhile, Jack is forced to play Santa in the hospital - though he later plays Santa out of the goodness of his heart; and Hank realizes that he had made arrangements to work on Christmas months prior.

Jack's son visits and announces he is going to Guatemala with the Peace Corps -- a decision that doesn't sit well with Jack. Meanwhile Hank, worn out from being a new parent, oversleeps and doesn't get the baby to the babysitter. Instead of letting Gina think he's irresponsible, he convinces his co-workers to tend to the baby without letting Gina find out.

Jack and Paco sneak off to Bassau on Jack's jet, only to be hijacked by a disgruntled employee; Casey loses a contact lens but is too vain to wear her glasses.

A new doctor frames Greg for the theft of some missing drugs; Sandy gets made at a patient who is ignoring her mother; and Annie worries she may be pregnant.

Annie's boss tells her she has to drop her plans and cover a shift, so Annie tells her to drop dead -- and she does.

Sandy's mother arrives for a visit and immediately starts to complain; Gina is upset to learn Hank is dating other women.

Paco becomes indebted to a mob boss; Gina tries to make Hank jealous by dating another man, unaware that he is gay.

Gina realizes Hank is still carryin a torch for his ex-wife; Greg is trapped in the elevator with a cannibal.