The Busbys wade back into potty training, determined not to be defeated this time. Blayke takes gymnastics lessons & enjoys one-on-one time with her parents. Mimi distances herself from the family as she struggles with the loss of her house.

Adam’s left in charge of all six kids for the weekend, as Danielle goes out of town for a work conference. Even though parenting solo is overwhelming, he has big plans in store for his little ladies. A routine eye checkup for Hazel delivers shocking news.

A family member suffers a devastating loss when Hurricane Harvey hits; Danielle and Adam are split on what to do about Olivia escaping from her crib; and Danielle may have to work through the fun when it’s time for the simple pleasures of Halloween.

The Busbys plan a special Thanksgiving, but bad news for Mimi may throw the holiday into turmoil. When Adam and Danielle find out that Riley and Parker are moving up to a different classroom, Adam struggles with the idea of separating the quints.

Danielle and Adam want to give their daughters the best Christmas, but as their plans crumble, so does Danielle.

Blayke hopes to turn a profit with her business; Danielle's stress gets worse; Adam reveals the truth about his vasectomy.

Danielle begins the new year by making a chore chart to teach the kids to help around the house, but wonders if this will remedy her exhaustion or double the quints' tantrums; the girls enter a fashion show.

As Danielle's health concerns grow, Adam reveals a bombshell secret that could mean she's actually pregnant; the couple's stress skyrockets when one of the quints goes missing; Blayke opens a lemonade stand and the entire family is ready to help.

Adam faces the challenge of pleasing his wife and all six of his daughters for Valentine’s Day. Later, Adam and Danielle are stunned by what they learn at Hazel’s doctor appointment.

Danielle is ready to get the girls into underwear, but Adam is worried; Mimi asks to meet up with Danielle.

Adam and Danielle hope teaching the quints to share will stop their constant fighting; Blayke has a gymnastics evaluation but one wrong step may cost her the chance to move up; the Busbys step in to help a family hurt by the hurricane.

The Busbys throw a joint birthday party for the girls, but Danielle also plans individual birthday outings! When Adam's job causes him to miss out on the fun, he faces a big decision. A familiar guest scares the girls at the Busby Easter celebration.

The Busbys head to Hawaii! But it's trouble in paradise as the quints have constant meltdowns and Riley gets lost. Danielle and Adam face a tough decision as his desire to quit his job grows. Hazel returns to the eye doctor with surgery looming.