Brain enlists the aid of beavers to gain control over the flow of rivers.

The mice make a series of comedy films and hit the big time.

Pinky and Brain have a new companion, Larry, but their newest plan just doesn't seem to pan out.

In their latest plan, Pinky and Brain try to take over the steel mills in Pittsburgh, Pennsylvania by pretending to be a part of an endangered species called the Mousealopes.

It's 1946 and Brain's new plan gets interrupted when he and Pinky encounter Billie and Snowball.

Brain gets caught up in winning a golf tournament, even though it interferes with his new plan.

After the Earth gets the power of speech from his Silitronlinguifactor device, Brain comes up with a new plan.

Brain tries to get a package meant for him back from his neighbor.

Pinky becomes a guru during the 1960s.

It's Brain's birthday and Pinky plans a surprise party.

After getting a glimpse of his future, Brain abandons his attempts to take over the world and gets a job as a ski instructor.

The mice are looking to control tornados, but a pest keeps getting in their way.

Brain sings about past and present world leaders' failures.

The mice need to get into a mine, but have to pretend to join a Amish-type society.

Brain's latest plan is a conspiracy theory about why he is not ruling the world.

Brain becomes a tap dancer with steam-powered legs in order to spread a subliminal morse code at the World's Fair.

Brain is out of ideas for taking over the world, so he tries to get some from writers.

Farmer Brain tries to grow an army of monster vegetables.

Brain creates a cloning machine and plans to clone himself in order to create the best Celtic dance troupe the world has ever seen.

Brain masquerades as a fashion designer.

Brain plans to use the Personalitron to give him irresistible charisma, but it winds up going to Pinky.

The mice learn of a secret organization, T.H.E.Y. (comprised of world leaders), and try to get in.

A house needed for Brain's latest plot becomes the set of a reality series about the people living there. So the mice become participants to get in.

To save his Las Vegas casino, Brain works as a lounge singer.

Mr. Itch offers Brain control of the world in exchange for his soul, but Brain refuses. In a shocking twist, Pinky sells his soul to make it happen and Brain soon decides to get his friend back.