Hurricane Isaac batters New Orleans, flooding Villalobos' evacuation location and isolating Tia from the rest of the world.

It's a whole new world for Tia, her family, the parolees, and most importantly, her pitbulls, when they packs up their lives ahd moves across country to New Orleans. But the move is only the first of many challenges Tia faces.

Return adopters visit Villalobos to find a dog that will feel at home on their boat. Tania and Mariah head out to rescue a stray that is hiding beneath a shipping container. And, parolee Jammall starts to slip up, risking his future at the rescue.

Tia brings in reinforcements to rescue a dog from a dangerous part of New Orleans. Tania is left stunned when she becomes the center of attention at her boyfriend's birthday party.

It's a time of celebration as Armando's wedding day approaches, but even on this happy occasion the dogs come first. When a rescue mission becomes more than she bargained for, Tia is the one racing to the altar, not wanting to miss Armando's big day.

Tia's daughter faces a difficult decision when her beloved dog's health takes a turn for the worse. Then, Tia sends her team to rescue a mother pit bull and her puppies from horrific conditions in an abandoned home.

After a tornado rips through the heart of Alabama, Tia and Tania head south to help a devastated dog rescue pick up the pieces. Meanwhile, back at Villalobos, Mariah oversees her first solo puppy adoption when a young couple visits the ranch.

Tia meets a family of eight looking to adopt a new dog after losing theirs to cancer. Then, a rescue-call takes Tia and her daughter Tania into New Orlean's infamous ninth ward to face off with a snarling, sick dog.

Tia and her rescue team land in a dangerous situation when an anonymous tip leads them toward a dog-fighting ring; one lucky pit bull awaits permission to enter a new home.

Tia sends Jake and Armando on a rescue mission to Texas, after hearing about two pit bulls who were wounded in a run-in with a porcupine. Then, when a second story about a dog in death row comies in, the guys need to kick it into high gear.

Three roommates contact Tia about adopting a pit bull who can fit in with their extreme, fast-paced lifestyles. And, the parolees are sent running for cover when they uncover three beehives.

Tia, Mariah, the twins and the parolees launch a massive rescue effort to track down a pit bull and her puppies that have been dumped in the Mojave Desert.

A pit bull is saved from drowning in a canal by a young girl after it evaded Tia for weeks; Tia must hire another parolee when twenty new puppies arrive at Villalobos.

Tia addresses her lazy parolees, which leads to a fiery confrontation with Randy; a strange-looking dog is rescued from the searing heat.

Memphis Grizzlies basketball star Zach Randolph contacts Tia about a dog that was rescued from a drainpipe; Mariah and Earl ready a puppy for adoption.

A dangerously ill dog is rescued by Tania and Tia from the streets of New Orleans. Villalobos favorite, Chong, takes a turn for the worse as his cancerous tumor grows. And Tia offers to help with a long distance adoption in New York City.

Tia recruits the twins and newly-hired work release prisoner to rescue a pit bull from the bottom of a 40-foot hole. Then, Mariah helps Tia with a heart-wrenching adoption to a young couple reeling from the tragic loss of their dog.

A dangerous rescue mission is launched to secure two dogs spotted running wild on the train tracks next to the rescue center. And, a husband and wife come looking to adopt a dog to help them heal after a crippling accident.

Tia and the twins try to make the best of a bad situation after they learn of Chong's cancer diagnosis.

Tania oversees the rescue of 10 dogs left to die in deplorable conditions. Tia helps a family find the perfect companion for their special needs teenager. The adoption takes a turn for the bizarre when Tia learns about the family's large, exotic pet.

After a teenager is attacked by a group of pit bulls, Tia finds herself thrust into a rescue mission to save an innocent pit bull caught up in the media storm.

Tia and Jake are determined to find one of Villalobos' most unique-looking pit bulls a new home but when a promising adopter backs out, they are forced to step up their efforts. Parolee Billy is causing tension at Villalobos and Tia must intervene.

A parolee goes off track, forcing Tia to make a hard choice; a short-term home is needed for a dog whose owners' home was ravaged by a fire.

Tia goes to Nashville with Tania and a new parolee to rescue a dog that's about to be put down. Meanwhile, back in New Orleans, Mariah tries to keep Villalobos safe during a storm; and a puppy rescued from the 9th Ward may find a new home.

Tia and the twins board a boat to rescue a dog abandoned in a swamp outside New Orleans. Meanwhile, a young parolee is stressed out by work and parenthood.