Jesse finally comes face to face with Deblanc and Fiore and learns about the mysterious entity that has taken over his body.

It is the day the entire town has been waiting for, as Jesse tries to follow through on his promise to get answers from Heaven.

God maneuvers the chess pieces of His apocalypse closer to the endgame as Jesse takes off in search of a mysterious rock formation that may be the final leg of his journey. Meanwhile, Tulip devises one last-ditch effort to try and save Cassidy from his endless torture.

Tulip forges an unexpected alliance to save Cassidy; Jesse finds himself stranded.

Tulip reunites with Cassidy and Eugene finds Jesse; the Grail's agenda threatens to unwind.

Tulip and Cass tear after God; an old friend presents Jesse with an unique opportunity.

Tulip and Cass struggle to keep Humperdoo hidden from the Grail, while Jesse remains MIA.

Jesse, Tulip and Cassidy mount one final assault on Masada as the Apocalypse Revue begins.

The curtain falls on the Apocalypse Revue as the fate of the world is decided, and the long journey of a preacher and his friends comes to an end.

Jesse, Tulip, and Cassidy track a lead from Heaven. The trio tries to find out who the Cowboy is and why he's attempting to kill them.

The Saint corners the trio. Jesse makes a deal with the killer Cowboy. Jesse races to save Tulip and Cassidy.

Annville, Angelville and the Grail team up to steal souls in New Orleans and Osaka in a last-ditch effort to satisfy Gran'ma and save the world.

Jesse is on the run while those around him face life-altering decisions. The Cowboy returns to Ratwater to exact his revenge.

Jesse, Tulip and Cassidy hit a bump in the road and decide to leave New Orleans. An old foe resurfaces and causes a change of plans.

Jesse questions the path ahead. Tulip uncovers a dangerous secret. Cassidy struggles with a difficult truth.

Tulip gets in too deep in Masada; Cassidy reflects on a lost life; the Saint closes in on Jesse.

Jesse struggles to escape a past that is slowly catching up to him. A mysterious entity comes to earth, leaving a wave of destruction in its wake.

Jesse gets a much-needed breakthrough on his search for God. Tulip continues to spiral and Cassidy makes a life-altering decision for Denis.

Tulip and Cass track Jesse and the Saint of Killers, while Starr searches for the missing messiah.

Jesse, Tulip, and Cassidy begin the search to find God. The trio realize they are being followed by a killer cowboy from Hell.

Jesse, Tulip, and Cassidy get a tip that God may be in New Orleans. Tulip is hiding a secret and their stop in New Orleans risks exposing her.

Tulip confronts her near-death experience. Denis asks Cassidy for a favor. Jesse questions the price of saving Cassidy and Tulip.

As Jesse helps reinvigorate business at Angelville, he tests Tulip and Cassidy's faith in him when Angelville brings out a darker side of him.

As Cassidy falls in with a group of mysterious strangers in New Orleans, Tulip and Jesse deal with the fallout of a failed escape from Angelville.

Jesse, Tulip, Gran'ma and Starr form an uneasy partnership to avert the apocalypse; Cassidy learns to love Eccarius, but at a cost.