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While the team is closing in on drug lord Mark Desmedt, John discovers that Chief Inspector Rabet and Serge are both working with the criminal. Professor T asks Annelies to assist him with his research in determining the exact profile of a murderer. He wants to find out whether Flamant will be capable of murder when she finds out that her new boyfriend is not what he appears to be.

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A student at a strict Catholic boarding school is found dead in her room. At first the team assume it is a case of erotic asphyxiation gone wrong, but could there be another explanation? Gijselbrecht and Flamant have an interesting meeting. Annelies' father is laid to rest and her colleagues are there to show their support along the way. Rabet returns.

15 years ago, Flamant solved a series of murders by a masked killer. Now an identical crime has been committed. Is it a copy-cat or did Flamant catch the wrong person? Rushed to hospital for surgery, Professor T helps Flamant from his sick bed. Annelies father shows up, completely disorientated and Annelies realises she needs to look for a proper long-term solution.

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A man is found by a dogwalker in a forest; his face severely torched, it seems he has been strangled to death, curiously he has the year 1991 carved into his chest. Days later a second victim is found also with a number carved into his chest - Does Antwerp have a serial killer? Where is Professor T when you need him?

With Daan fighting for his life in hospital, the search for the killer continues. Annelies meets with the widow of the third victim, urgently trying to find connections between the three murders. Unbeknownst to the team, he is much closer by than they could possibly imagine and has in fact already infiltrated the Department of Criminology.

Much to the dean's dismay, Professor T refuses to appear as the second speaker at the annual conference of criminologists. Following the murder of the headliner, the event descends into disarray. Annelies and John's relationship improves, he has gained her trust: she tells him that she burned her father's living will and that she now regrets it. To her amazement, John has a simple solution.

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A physician, his wife and two children are found dead. It is unclear to the team which one of them was the killer of the other three and therefore which of them committed suicide. Professor T is having nightmares and suffering from hyperventilation; is this a result of his therapy? Annelies makes a shocking discovery about her father and Rabet receives startling news.

A jeweler's family is taken hostage while the jeweler is on his way to empty the safe at his shop; an accident en route raises suspicion. Professor T is going through a rough patch and considers quitting therapy. Not only has he been unable to prevent a fatality, he's also admitted to hospital after an accident at a public swimming pool. Since his departure, Flamant has assumed Rabet's duties.

Jitske, a 17-year-old girl with Down syndrome, claims she knows who murdered her mother, but she doesn't want to say who it is. When Annelies shows insensitivity towards the girl, John decides it's time for her to meet his daughter, Elke. Professor T finds that Flamant is being overly friendly and it is making him nervous, especially when she confides in him about her upcoming divorce.

Professor T's classes are proving popular. The material he presents is like a thriller that has the students on the edge of their seats and they start flocking to his class in increasing numbers. Annelies receives confirmation that her father's euthanasia request is legally valid and that she has been named trustee. Struggling with this heartbreaking decision, she turns to John for support.

An undercover agent, who is embedded in the drug scene, is found dead in the trunk of his car. The target of the investigation is drug lord Mark Desmedt, but could this be too obvious a suspect? At the university it is Professor T's birthday, catalyzing his odd behavior and visions. Meanwhile Annelies' career comes to a crossroads and she makes a big decision.

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The call girl who visits Professor T is found dead in her apartment. The police believe she has committed suicide, but Professor T is not so sure and hides the fact that he knows the victim to stay on the investigation team. Inspector Rabet is back and he hasn't forgotten that Professor T betrayed him in front of his colleagues and Annelies and Daan are not speaking to each other.

Chief inspector Rabet gets into serious trouble when he's confronted with the man who killed his daughter in a car crash. The man in question is thought to be involved in a crime and while Rabet is certain he's guilty, his colleagues are less convinced. Meanwhile Professor T is taking oral exams and finds an unlikely investigation aid in one of his students.

A man is accused of killing his boss, having been found standing over the body, Annelies and her investigation team are convinced he is guilty. However, following a presentation by Annelies to his students, Professor T has questions if they have the right man. Flamant finds herself in hot water, sparks fly between Daan and Annelies.

After six months in an institution Professor T is released on one strict condition. Daan returns to the office, but things are not easy and Annelies' guilt puts their relationship under strain. However, the old team are back, and their help is needed; a number of fatalities have been linked to eating poisoned sweets, and the trail leads to the manufacturing company.